Prasad AS, Beck FW, Bao B, et al: Zinc
Supplementation Decreases Incidence of Infections in the Elderly: Effect of Zinc on Generation of Cytokines and Oxidative Stress.
The case was made that while
decreased chronic disease
incidence is clearly associated with generous dietary intake of vitamin E (mixed tocopherols and tocotrienols),
supplementation with high - dose α - tocopherol alone, whether natural (RRR) or synthetic (all - rac), may promote potentially harmful imbalances in inflammatory and detoxification pathways.