Sentences with phrase «systemic cytokine levels»

Systemic Cytokine Levels Do Not Predict CD4 (+) T - Cell Recovery After Suppressive Combination Antiretroviral Therapy in Chronic Human Immunodeficiency Virus Infection.

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They both had considerable systemic inflammation, which can be measured by levels of multiple pro-inflammatory cytokines in the blood serum.
Consistent with other investigators, 22,58 there were not reliable relationships between the local production of cytokines at inflammatory sites and levels in systemic circulation (data not shown); thus, local production is the primary presumptive pathway.22, 58
Although greater early local production of proinflammatory cytokines at wound sites is beneficial because it is associated with enhanced healing, greater systemic production of proinflammatory cytokines can represent a maladaptive response.24 Both physical and psychological stressors can provoke transient increases in plasma levels of proinflammatory cytokines, particularly IL - 6,25 as can negative emotions like depression and anxiety.26 - 28 More frequent or persistent stress - related changes have broad implications for physical and mental health; sustained elevated levels of proinflammatory cytokines have been linked to a variety of age - related diseases, including cardiovascular disease, osteoporosis, arthritis, type 2 diabetes mellitus, certain cancers, and frailty and functional decline.29 - 31
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