Sentences with phrase «systemic effects of»

These systemic effects of global warming came together to produce the ferocity and magnitude of Hurricane Sandy.

The paintings selected are a portrait not only of a people, but also of a place and time that is continuously fighting the systemic effects of marginalization — much like the artist herself.

Demonstrating that there are systemic effects of non-specific dietary sensitivity.

Clinical signs in patients with pancreatitis are either due to activity of prematurely activated pancreatic enzymes or to systemic effects of the inflammatory response to pancreatic autodigestion.

Systemic effects of AIGFP, and do you hae a link on the FRC Basel issue?

In fact, though, the systemic effects of school choice policies depend first on the local context in which the policies are implemented and second on the rules that govern the choices of parents and schools.

Competition from the Choice program appears to have boosted the test scores of students who remained in Milwaukee Public Schools (MPS), but those systemic effects of the program were modest in size.

Based on human and animal research, it appears a variety of nutritional and botanical substances - such as adaptogenic herbs, specific vitamins including ascorbic acid, vitamins B1 and B6, the coenzyme forms of vitamin B5 (pantethine) and B12 (methylcobalamin), the amino acid tyrosine, and other nutrients such as lipoic acid, phosphatidylserine, and plant sterol / sterolin combinations - may allow individuals to sustain an adaptive response and minimize some of the systemic effects of stress.

The systemic effects of stress include increased levels of stress hormones such as cortisol, a decline in certain aspects of immune system function such as natural killer cell cytotoxicity or secretory - IgA levels, and a disruption of gastrointestinal microflora balance.

Based on human and animal research, it appears a variety of nutritional and botanical substances — such as adaptogenic herbs, specific vitamins including ascorbic acid, vitamins B1 and B6, the coenzyme forms of vitamin B5 (pantethine) and B12 (methylcobalamin), the amino acid tyrosine, and other nutrients such as lipoic acid, phosphatidylserine, and plant sterol / sterolin combinations — may allow individuals to sustain an adaptive response and minimize some of the systemic effects of stress.

The majority of underlying gut problems come with little to no gut symptoms but only the systemic effects of it somewhere else in the body.

Infusion of an oxytocin blocker to the brain region blocked the systemic effects of oxytocin, driving home the necessary role of the nucleus accumbens for oxytocin's effects.

The article, «Systemic effects of a high saturated fat diet in grizzly bears (Ursus arctos horribilis)» by Danielle Rivet, Lynne Nelson, Chantal Vella, Heiko Jansen, and Charles Robbins was published today in the Canadian Journal of Zoology.

The underlying mechanism appears to be a systemic effect of elevated CO2 on cognitive function and decision making in marine fish.

Not exact matches

With much of the economy dependent on them, further consolidation could have serious systemic effects.

«Major (cloud) infrastructure service providers are now also critical points for systemic failure, and any data breach or significant downtime can have a cascading effect impacting thousands of businesses, with a great potential for economic impacts,» Goddjin observes.

Think of this massive liquidity as having the effect of acting like a «pain killer» on systemic problems percolating like a cancer beneath the surface.

These factors — many of which are beyond our control and the effects of which can be difficult to predict — include: credit, market, liquidity and funding, insurance, operational, regulatory compliance, strategic, reputation, legal and regulatory environment, competitive and systemic risks and other risks discussed in the risk sections of our 2017 Annual Report; including global uncertainty and volatility, elevated Canadian housing prices and household indebtedness, information technology and cyber risk, regulatory change, technological innovation and new entrants, global environmental policy and climate change, changes in consumer behavior, the end of quantitative easing, the business and economic conditions in the geographic regions in which we operate, the effects of changes in government fiscal, monetary and other policies, tax risk and transparency and environmental and social risk.

But by the time my semester came to an end, I learned some wholly unexpected lessons about the transformative power of prayer in a jail setting; about the effects on the body of such personal transformation; and about this country's systemic racism and how it is in some ways coterminous with the attempt to prevent or repress such transformation.

In other words, rather than a systemic interpretation of the problem leading to a systemic view of its solution, the systemic diagnosis provides a framework that says, in effect, this is the way it will always be, and then individual attributes are credited with causing people to stay in poverty or to move out of it.

I am less interested here to press my description of the particular values that inhere in academic life than I am to insist that, whatever their identity, they are built into the institution's spatial and temporal forms, its patterns of behavior, and its ideological set; and that value, both systemic and sentient, has a profound socializing effect.

More people are experiencing systemic candida (when the problem spreads throughout the body and causes a myriad of unpleasant side effects).

The contribution of bacteria through vaginal delivery followed by exclusive breastfeeding promotes specific microbial profiles that facilitate optimal nutrient metabolism and early systemic immune training.23 The potential short - and long - term effects of perturbations of the gut microbiome of infancy, as influenced by operative delivery or formula feeding, are beginning to be examined.

Therefore, not only would the national economies of the periphery suffer in such a scenario but the systemic effects would be incalculable.

In the context of systemic risk due to banking panics, the Federal Deposit Insurance Corporation has the political effect of giving bankers an overpowering incentive to influence the Federal Reserve System's Federal Open Market Committee and the Federal Reserve Board of Governors to implement system wide policies for extension of credit which socialize and cartelize the banking sector to work towards its own common purpose.

«Our study does not answer the question on possible reasons for infertility but it shows that periodontal bacteria may have a systemic effect even in lower amounts, and even before clear clinical signs of gum disease can be seen,» says Dr. Paju.

This study delivered the drug via a local injection to avoid any potential systemic effects from inhibiting a component of the immune system.

However systemic administration of NPY will likely have undesirable side effects, especially on the cardiovascular system.

Regular sauna bathing improves endothelial function, i.e. the function of the inside layer of blood vessels, which has beneficial effects on systemic blood pressure.

The beneficial responses were associated with an increase in systemic dendritic cells, which in turn increased the expression of interleukin 12 (IL - 12), which sustained expansion and anti-tumor effects of transferred T cells.

Because high serum levels of MCP - 1 cause the white cells and osteoclasts to be stimulated, this process could have systemic effects as well as effects on bone.

«Being able to increase the responsiveness of peripheral opioid receptor systems could lead to a reduction in systemic opioid administration, thereby reducing the incidence of side effects.»

New research published in Environmental Toxicology and Chemistry addresses the effects of two broad - spectrum systemic insecticides, fipornil and imidacloprid, on honeybees.

Increased irisin levels in circulation upon systemic administration can recapitulate part of the beneficial effects of exercise in the skeletal system,» said senior study author Jake Chen, D.M.D., M.D.S., Ph.D., professor and biological sciences researcher at TUSDM.

dSysMap (which stands for «Disease - mutations Systemic Mapping») is a computational tool to interpret the effect of genetic mutations on the development of complex diseases.

«This cascade of molecular actions reduces inflammation in the fat tissues and produces a systemic domino - effect with dramatic benefit in multiple organs.»

Viral vectors have the main adverse effect of inducing neutralizing antibodies, while several non-viral vectors present toxic effects (e.g. respiratory system).14, 15 In an effort to deliver efficiently the necessary drug concentration to the tumor site and prevent systemic adverse effects, the concept of administering local treatment for lung cancer has been explored.

Systemic enamel pathologies may be due to anti-androgenic effects of some endocrine disruptors.

The Tissue Platform workgroup within autoimmune inflammatory diseases at Karolinska Institutet studies the effects of probes in cell assays relevant for the diseases we study, ie systemic lupus erythematosus, idiopathic inflammatory myositis, systemic sclerosis and inflammatory bowel disease.

(It should be noted that the knockdown of the TOR pathway in the fat body severely affects larval growth [8]; therefore, Lsp2 - GAL4, which is expressed in the fat body at the wandering stage — after the growth period [13]-- was used to overexpress TSC1 / 2 in order to avoid secondary effects from a systemic growth defect.)

The findings support the results of previous studies that have suggested that genetic differences in height result principally from their effect on local regulation of the growth of long bones, rather than on broader, systemic processes.

Systemic antitumor effect and clinical response in a phase 2 trial of intratumoral electroporation of plasmid interleukin - 12 in patients with advanced melanoma.

«SB50 takes the powerful clotting ability of this snake venom and makes it far more effective by delivering it in an easily localized hydrogel that prevents possible unwanted systemic effects from using batroxobin alone.»

The possibility that they also stimulate a regional and even systemic immune response is exciting, as this potential effect may have utility in combination regimens; such regimens are an area of active research.

Our ability to detect anti-HER2 antibody at the tumor site but not in the blood of NSC - treated mice suggests that this approach could have robust localized anti-tumor effect, while minimizing the systemic toxicity associated with traditional trastuzumab therapy.

Although the specific effects or consequences of FMc remain to be demonstrated in healthy women, FMc has been implicated in «alloimmunity» in some classically autoimmune diseases, for example systemic sclerosis and thyroiditis [8], [10]--[12].

Perhaps the greatest attraction and chief benefit of intratumoral therapies is their ability to synergize with systemic checkpoint therapies and accelerate the development of a lymphoid infiltrate and perhaps secondary lymphoid structures in vivo, which in turn can result in systemic mobilization of a T - cell response: the local injection — global effect model.

This study established the MTD of the cyclophosphamide - huKS - IL2 combination (mainly limited by IL - 2 side effects), the pharmacokinetics of huKS - IL2 and its systemic immunologic and immunogenic effects in patients with solid tumors (BMC Cancer.

Instead of acting like «shotgun blasts,» as the older systemic drugs do, the biologics are «much more like a rifle shot, where theres a whole lot less collateral damage and fewer side effects,» says David M. Pariser, MD, president - elect of the American Academy of Dermatology.

In comparison to some of the newer psoriasis drugs on the market, Kavlick says, «these systemics have been around a lot longer, so we know a lot more about their long - term effects and what to watch for.»