Sentences with phrase «systemic responses increase»

Systemic responses increase as the financial stakes grow.

Not exact matches

Those introduced in response to emergencies or to address systemic financial risks will be exempted, allowing the government to increase the regulatory burden on the financial sector.

Further experiments confirmed that these increases in IgT and IgT - producing B cells were specific to the gills and not the result of a systemic increase in production, showing for the first time that a non-mammalian species can locally induce a dedicated mucosal immune response.

The beneficial responses were associated with an increase in systemic dendritic cells, which in turn increased the expression of interleukin 12 (IL - 12), which sustained expansion and anti-tumor effects of transferred T cells.

Lastly, increased systemic inflammation seen during ageing is also apparent in chronic infections such HIV or cytomegalovirus, 10,15 obesity7 and individuals enduring chronic psychological stress.16 Similarly, the main features of immunosenescence are apparent in many of these conditions, including decreased antibody responses, increased infections, malignancies and also incidences of inflammatory associated disorders such as cardiovascular disease.7, 10,15,16 Inflammation and premature immunosenescence are, therefore, prevalent features of many common conditions of modern life, such as obesity and stress, and could have negative health consequences for large proportions of society well before old age is reached.

Both factors may elicit a sympathetic and hypothalamic — pituitary — adrenal (HPA) axis response, which drive increased systemic reactive oxygen species production, chronic inflammation, and a metabolic substrate shift toward carbohydrate and away from fat oxidation, manifesting in an array of signs and symptoms often labeled as the overtraining syndrome.16

They can overburden our liver and kidney's detoxification pathways, activate the stress response, promote insulin resistance, inhibit thyroid function and increase systemic inflammation — all leading to excess weight, hormonal imbalances, distress, chronic conditions and mood disorders.

According to AHA's scientific statement on pet ownership and cardiovascular risk the beneficial effects of pet ownership include «increased physical activity, favorable lipid profiles, lower systemic blood pressure, improved autonomic tone, diminished sympathetic responses to stress, and improved survival after an acute coronary syndrome.»

As part of this homeostatic mechanism, the initial response of the body to compensate for decreased MAP is to bring it back up to normal by increasing systemic vascular resistance, by vasoconstriction.

Although greater early local production of proinflammatory cytokines at wound sites is beneficial because it is associated with enhanced healing, greater systemic production of proinflammatory cytokines can represent a maladaptive response.24 Both physical and psychological stressors can provoke transient increases in plasma levels of proinflammatory cytokines, particularly IL - 6,25 as can negative emotions like depression and anxiety.26 - 28 More frequent or persistent stress - related changes have broad implications for physical and mental health; sustained elevated levels of proinflammatory cytokines have been linked to a variety of age - related diseases, including cardiovascular disease, osteoporosis, arthritis, type 2 diabetes mellitus, certain cancers, and frailty and functional decline.29 - 31