Sentences with phrase «t cell motility»

Taken together, these results strongly suggest that the LPA2 signaling modulates T cell motility in the confined environments at least partly in an integrin - independent manner and may also act on cell adhesion to prevent over-adhesion to the substrates.

Following this comment, we examined the dependency of ROCK / myosin II in the LPA - mediated T cell motility in a collagen matrix and found that LPA - induced T cell motility was abrogated by the treatment of T - cells with blebbistatin or the Rho kinase inhibitor Y27632.

PKC$ þeta $ Regulates T Cell Motility via Ezrin - Radixin - Moesin Localization to the Uropod.

Not exact matches

What drove the motility response in T cells was synthesis of hydrogen peroxide, which then activated a signaling pathway that increases Tcell movement.

In Enpp2fl / fl mice, Lpar2 - / - T cells had significantly less intranodal motility than WT cells (Figure 5E, G and Figure 5 — figure supplement 3A, B).

In Lpar2 - / - T cells, CCL21 did not enhance motility in the presence of LPA (Figure 9B, C).