Sentences with phrase «t cell polarization»
More recently, another HDAC inhibitor, ITF2357, was shown to modulate IL - 6 — dependent CD4 + T cell polarization into Th17 cells through targeting the IL - 6 / STAT3 / IL -17 pathway, and it reduced the severity of experimental colitis (49).
http://www.jimmunol.org/ Not exact matches
In the last few years, our group has shown that the ZAP70 kinase and its substrate LAT control the polarization of T cells toward the APC and that LAT trafficking to the IS depends on the SNARE protein VAMP7.
It is characterized by a remodeling of the cytoskeleton of T cells that leads to the polarization of T cells toward the APC.
Diacylglycerol promotes centrosome polarization in T cells via reciprocal localization of dynein and myosin II.
Linker for activation of T cells, ζ - associated protein - 70, and Src homology 2 domain - containing leukocyte protein - 76 are required for TCR - induced microtubule - organizing center polarization.
Sun H, Kim D, Li X, Kiselinova M, Ouyang Z, Vanderkerckhofe L, Shang H, Rosenberg ES, Yu XG, Lichterfeld M. Th1 / 17 polarization of CD4 T cells supports HIV - 1 DNA persistence during antiretroviral therapy.
More specifically, he researches the use of anti-CEA antibodies for tumor imaging and therapy, as well as the role of CEACAM1 in T - cell activation and mammary epithelial cell polarization.