Sentences with phrase «t cells of the immune system»

The blood transports nutrients and the T cells of immune system to the painful area.

In case of inflammation, the T cells of the immune system reach the inflamed area and heal it quicker.

The T cells of the immune system travel with the blood.

The same goes for nutrients and the T cells of the immune system.

The quicker blood flow to the area means the T cells of the immune system can travel quicker to the muscle, hence the area recovers quicker from inflammation.

During inflammation the T cells of the immune system can reach the inflamed areas quicker.

When the T cells of your immune system are forced to deal over time with cancer or a chronic infection such as HIV or hepatitis C, they can develop «T cell exhaustion,» becoming less effective and losing their ability to attack and destroy the invaders of the body.

The lack of the enzyme causes a build - up of toxins which stop the T cells of the immune system from maturing.

The drug forms a complex with cyclophilin A and a third protein, calcineurin, which is needed to activate the T cells of the immune system.

Once inside a T cell of the immune system, zidovudine relies on enzymes within the cell to attach phosphate groups to it before it is ready for action.

In vitro experiments indicated that the antihistamines work by suppressing the accumulation and function of dendritic cells, which take up peanut protein and present it to T cells of the immune system.

In fact, one of the mysteries remaining for BanLec work is just how the T cells of the immune system actually attach to it.

«Patentiflorin A was able to inhibit the action of RT much more effectively than AZT, and was able to do this both in the earliest stages of HIV infection when the virus enters macrophage cells, and alter infection when it is present in T cells of the immune system,» Prof. Rong said.

Not exact matches

Hoping to learn something about how the human body defends itself against cancer, he had zeroed in on a complex regiment of lymphocytes called T cells, common to the immune systems in both mouse and man.

Rather than an activator of T cells, the molecule acted like a brake, stopping the immune system from its attack.

These vitamins are responsible for a number of bodily functions that ward off winter illness, including the regulation of T cells (or immune system warriors) and counteracting stress hormones that lower immunity.

A decade ago a drug based on an internal protein of the flu virus, called NP (for nucleoprotein), set the immune system's killer T cells into action, but it only partially protected mice from the flu.

«Our lab specializes in developing novel genetic methodologies to study T cell repertoires, but we had never applied this technology to study how the immune system responds to an infection,» says Emanual Maverakis, M.D., associate professor of dermatology at the University of California, Davis School of Medicine.

And a new analysis of the STEP trial, published last November in Proceedings of the National Academy of Sciences USA, provides a warning that the very vectors (adenoviruses, which are also employed in other vaccine development work) used to distribute the inactive HIV strains can actually make the immune system more vulnerable to infection by recruiting susceptible T cells to mucous membranes, where they are more likely to be infected during sexual activity.

Previously, Derek Danahy of the University of Iowa and colleagues showed that sepsis disrupts the immune system by reducing the amount and function of memory T cells that circulate throughout the body, recognizing and attacking specific bacteria, viruses, or cancer cells.

We now know the virus attacks a person's T lymphocytes, a type of white blood cell that plays a central role in the immune system.

«These T - cells dampen incorrect responses of the immune system and have a strong anti-inflammatory effect.

A pre-clinical study of two drugs designed to boost T cell performance, has revealed the agents, when give in combination, may enhance the immune system's ability to kill melanoma tumors deficient in the tumor suppressor gene PTEN.

When the dendritic cells are activated, they train T cells — their allies in the adaptive arm of the immune system — to attack cancer cells anywhere in the body, whether at the site of the original tumor or distant metastases.

Thomas speculated that as many as 10 percent of T cell receptors are outliers that help the immune system recognize and rapidly respond to mutations that might otherwise help virus - infected cells and other threats delay detection.

A subset of immune cells that manage immune system suppression, known as regulatory T cells, begins learning to tolerate the fetal cells as non-foreign.

The immune system depends on molecules called T cell receptors on the surface of T cells to recognize and respond to foreign antigens from virus - infected cells, tumors and other threats.

Marta Monteiro and colleagues at the University of Lisbon, Portugal, studied mice protected from the animal equivalent of multiple sclerosis by natural killer T - cells (NKT), a class of white blood cell which helps to control the immune system.

Chronic HIV infection results in exhaustion of the immune system, a phenomenon characterized by dysfunctional HIV - specific killer T cells.

The current test is only able to analyze part of the human immune system, namely the B - cells but not the T - cells, which are needed as helper cells to fight the infection and whose activity indicates the presence of an infection.

In effect, PD - 1 may actually help to preserve a «reserve force» of T cells that can fight on later in the long - term cellular war between the immune system and foreign invaders or tumors.

The protein puts the immune system's brakes on, keeping its T cells from recognizing and attacking cancer cells, said Dr. Antoni Ribas, the study's principal investigator and a professor of medicine in the division of hematology - oncology at the David Geffen School of Medicine at UCLA.

Researchers at Nagoya University have been studying the therapeutic effect of T cells, vital disease - fighting components in our body's immune system, for fighting cancer.

A second type of immune system cell, called regulatory T cells (Tregs), are a model of constancy, remaining stable even as Teffs go into battle mode.

The so - called STEP trial, sponsored by pharmaceutical giant Merck & Co. and the federally funded HIV Vaccine Trials Network (HVTN), was the first to test the idea of stimulating the immune system's killer T cells to hunt for the virus more aggressively, in this case using a weakened form of the cold virus to carry three genes from HIV.

But if you put that same virus into a rhesus macaque, the monkey's immune system reacts similarly to that of humans; there is severe depletion of CD4 T cells and progression to AIDS, explains U.C.S.F. researcher Peter Hunt.

One advantage of this method is that it only activates a certain type of immune cell, the dendritic cell or T - cell, and only in one part of the body, near the draining lymph nodes or tumor, which helps cut down on the system - wide side effects often seen with chemotherapy.

Researchers are developing many different versions of CAR - T cell therapies, but the basic premise is the same: Doctors remove a patient's T cells (immune system cells that attack invaders) from a blood sample and genetically modify them to produce artificial proteins on their surfaces.

In the presence of Acinetobacter and Akkermansia, they became a particular type of T helper cell, which trigger inflammation and help the immune system kill off invaders or infected cells, the researchers report today in the Proceedings of the National Academy of Sciences (PNAS).

The drug blocks CTLA - 4, a protein receptor on the surface of T - cells that serves as a molecular stop sign, preventing the immune system from going into overdrive.

Prompted by studies suggesting immune responses can help repair the nervous system, Kipnis and his colleagues created mice that lack CD4 cells, a kind of T - cell.

The T - lymphocytes, or T - cells, are a particular type of white blood corpuscle that is important to the immune system.

But roundworms seem to shift the balance of the immune system towards producing more type 2 T cells.

T cells, along with B cells and others, comprise the adaptive arm of the immune system, the body's second line of defense which quickly attacks and «remembers» specific pathogens.

Three of the genetic regions associated with PSC fall within a single biological system that underlies variation in T cells, cells important to our immune response.

This made it possible for their immune systems to produce sufficient amounts of CD8 T cells that were primed to attack and kill HIV - infected cells.

The researchers studied two types of cells called effector T cells, which activate the immune system to defend our body against different pathogens, and regulatory T cells, which help control the immune system and prevent it from attacking healthy parts of its environment.

Previous studies have found evidence that IL - 27 has a moderating effect on the Th2 response, and in general, keeps T - cells — the «battle tanks» of the immune system — from causing too much damage.

Converting these cells into regulatory T cells could help reduce the hyperactivity and return balance to the immune system, thus treating the root of the disease.

The patients received biweekly infusions of nivolumab, which is an antibody that blocks a protein called PD - 1 on the surface of immune system T cells.