Sentences with phrase «tim gannon»
By TIM BIRKHEAD The great auk has the dubious privilege of being the only species whose extinction is known precisely.
https://www.newscientist.com/
That gene's protein, called TIM, works with PER to drive the clock.
Newly named Nobel laureate Michael W. Young discovered that TIM, the timeless protein, pairs up with PER, the period protein.
In the Pfanner lab, Chacinska studied the communication between translocases in the outer membrane, called TOM, and others in the inner membrane, called TIM.
He discovered a second clock gene, called timeless, that encodes another protein, TIM, which is required for a normal circadian rhythm.
One of the first things we and others noticed was that whenever a fly was moved from a darkened incubator to one that was brightly lit to mimic day - light, the TIM proteins in the fly's brain disappeared — in a matter of minutes.
A fly traveling at 4 A.M. from San Francisco to New York, however, was making very little tim RNA before departure.
PER and TIM block the ability of CLOCK to turn on these genes at the same time as they are producing the oscillations of the central feedback loop — setting up extended patterns of cycling gene activity.
We used the tim and per genes to make PER and TIM proteins in the laboratory.
A fly moving at 8 P.M. from New York to San Francisco is producing maximum levels of tim RNA, so protein lost by exposure to light in San Francisco is easily replaced after sunset in the new location.
Studies involving mice also helped to answer a key question: What turns on the activity of the per and tim genes in the first place?
Jadwiga Giebultowicz of Oregon State University has identified PER and TIM proteins — key components of biological clocks — in the kidney like malpighian tubules of fruit flies.
What the fly experiences as a premature sunrise eliminates TIM and allows the next cycle of production to begin with an earlier schedule.
We knew this had to be a new gene, and we named it timeless, or tim.
These experiments revealed that the CLOCK protein targets the per gene in mice and both the per and tim genes in flies.
The per and tim genes are active until concentrations of their proteins become high enough that the two begin to bind to each other.
This move also caused TIM levels to drop, but this time the protein did not begin to build up again because the molecular clock was advanced by the time - zone switch.
The system had come full circle: in flies, whose clocks are the best understood, the CLOCK protein — in combination with a protein encoded by a gene called cycle — binds to and activates the per and tim genes, but only if no PER and TIM proteins are present in the nucleus.
Even more interestingly, we noted that the direction the flies traveled affected the levels of their TIM proteins.
We learned more about the mechanism behind the different molecular responses by examining the timing of the production of tim RNA.
TIM KELLY PHOTO A Cutchogue resident takes the old school approach to digging out from the weekend blizzard.
TIM KELLY FILE PHOTO Suffolk County Legislator - elect Al Krupski at a debate hosted by Times / Review Newsgroup earlier this month.
Story topics: buffalo / Erie County / hangman / Holding Center / inmates / jails / sheriff / suicide / tim howard
Story topics: 22 / accountability / buffalo / deaths / election / Erie County / Holding Center / inmates / leadership / sheriff / suicides / tim howard
TIM GANNON FILE PHOTO Suffolk County Executive Steve Levy hinted he might not seek re-election in a Times / Review interview conducted in his office last September.
TIM KELLY PHOTO Southold Town Supervisor Scott Russell «clarifies» some points on a gasification plant proposal.
TIM GANNON FILE PHOTO Jennifer Maertz (left) and Bridget Fleming are squaring off in a Democratic primary for the opportunity to oppose Senator Ken LaValle.
TIM KELLY PHOTO Supervisor Scott Russell addresses the town GOP committee during its nominating convention last month.
TIM KELLY FILE PHOTO The Southold Town Board could adopt a bill to zone Plum Island at its next meeting on Aug. 27.
Ajemian included in the memo a list of every tim the bill was proposed when Schneiderman was a state senator to show he was never a sponsor.
TIM KELLY FILE PHOTO Cutchogue's Sacred Heart Parish Church, which originally served the local Irish community, held its last Mass in January 2013.
TIM KELLY FILE PHOTO Supervisor Scott Russell delivering his «State of the Town» address earlier this year.
TIM KELLY FILE PHOTO Deputy Town Clerk Linda Cooper administering the oath of office to new Councilman Jim Dinizio last month.
TIM KELLY PHOTO Republican Town Justice William Price addressing Southold's Democrats, including party Chairman Art Tillman (left) and Deputy Chairman Bob Meguin.
TIM KELLY FILE PHOTO Al Krupski won the special legislative election and he resigned from his seat on the Southold Town Board.
Tim sureth a / k / a tim smith is a conman political hack who was nothing more than a gofer for the campaign manager.
But of course some people will present it as the former in order to confuse the public, for the reason tim stated in his answer.
1 TIM WOOLF ET AL., SYNAPSE ENERGY ECONOMICS, INC., INDIAN POINT REPLACEMENT ANALYSIS: A CLEAN ENERGY ROADMAP: A PROPOSAL FOR REPLACING THE NUCLEAR PLANT WITH CLEAN, SUSTAINABLE ENERGY RESOURCES 1 - 2 (Oct. 2012), available at http://www.riverkeeper.org/wp-content/uploads/2012/10/Synapse-Indian-Point-Replacement-Study-10-11.pdf
TIM KELLY PHOTO Jennifer Maertz says she won't run for Assembly this year, but plans to seek a state legislative seat in 2014.
TIM KELLY PHOTO Assembly hopeful Jennifer Maertz addresses the Southold Democratic Party during its May 29 convention.
TIM KELLY FILE PHOTO The district is looking into getting a camera to help improve school security at the front of the building.
TIM KELLY FILE PHOTO Republican Town Justice William Price addressing Southold's Democrats, including party Chairman Art Tillman (left) and Deputy Chairman Bob Meguin.
TIM KELLY PHOTO Democratic Councilman Al Krupski, who thinks Town Board districts would be counterproductive.
TIM GANNON PHOTO Suffolk County Executive Steve Bellone at Tuesday's press conference in Manorville.
TIM GANNON FILE PHOTO Suffolk County Executive Steve Bellone, center, and Legislator Jay Schneiderman, right, at a press conference earlier this year.
TIM KELLY FILE PHOTO Suffolk County Executive Steve Bellone became the latest public official to speak out against LIPA's response to Hurricane Sandy today.
TIM KELLY PHOTO Democratic candidate for Town Supervisor Steve Bellone addresses Southold Democrats last weekend.
TIM KELLY PHOTO New Southold GOP chairman Peter McGreevy (left) is congratulated on his appointment by Riverhead GOP leader John Galla following Monday's county Legislature debate at Martha Clara Vineyards.
TIM KELLY PHOTO New Suffolk Attorney Anthony Palumbo has secured the GOP nomination for state Assembly.
TIM KELLY FILE PHOTO Highway Superintendent Pete Harris was recognized for his decades of service to Southold Town Tuesday.