Sentences with phrase «tamoxifen does»

«The study shows that long - term use of Tamoxifen does not increase incidence of breast cancer in the opposite breast, but it may increase the proportion of oestrogen receptor negative cancers.

Not exact matches

When mice ate chow containing tamoxifen (about six to eight times the dose usually given to humans), the microglia didn't overreact and the photoreceptors were spared, the researchers found.

Of these variants, reported today in the journals Nature and Nature Genetics, 65 are common variants that predispose to breast cancer and a further seven predispose specifically to oestrogen - receptor negative breast cancer - the subset of cases that do not respond to hormonal therapies, such as the drug tamoxifen.

Kontos adds that a greater role for aspirin would be welcomed by many at - risk patients, as current drugs aimed at reducing risk, such as tamoxifen and raloxifene, have significant side effects and do not prevent ER - negative breast cancer.

«This means that tamoxifen, which is probably the best therapy for breast cancer available, is not working solely through blocking the oestrogen receptors, which everyone thought it did.

Tamoxifen, the estrogen antagonist, prevented the tumors from growing but did not cause them to shrink.

«We have found that the same genes responsible for tamoxifen resistance in our animals are also turned off in human breast cancer cells that do not respond to the drug,» she says «Because these genes were epigenetically silenced — meaning they were not irreversibly altered, just switched off — it was possible to turn them back on.

Because of this, this kind of breast cancer does not respond to treatments such as tamoxifen, which targets the estrogen receptor, and trastuzumab, which disrupts the HER2 receptor.

I am confused by tamoxifen; I understand how it works, but why does a post menopausal woman have so much estrogen floating around?

«Well, what they don't tell you is that tamoxifen is classified as a human carcinogen by the American Cancer Society and the World Health Organization.

In fact, studies show that turmeric is just as powerful as (if not more powerful than) the medical drug tamoxifen at blocking estrogen, and it does so without any toxic side - effects.

The drug tamoxifen, for instance, helps many women with breast cancer, but they pay the price of an increased risk of endometrial cancer.1 Medicine would do much better concentrating on genuine prevention — especially through nutrition.

Rather than wait and see for two long years only to resort later to drugs designed for breast cancer like tamoxifen and raloxifene or surgical reduction does not seem like a health promoting plan of action particularly for a young boy possibly already struggling with self esteem issues.

Five years ago today, I started taking Tamoxifen to lower my breast cancer risk (if you don't know my story, you can find it on my blog).