Sentences with phrase «tamoxifen inhibits»

But recent work shows that while these cancers lack estrogen receptors, progesterone receptors, and aren't driven by the gene HER2, up to a third of these tumors express the androgen receptor — clinical trials are underway to inhibit the androgen receptor in these tumors in much the same way that the drug Tamoxifen inhibits estrogen receptor in estrogen - receptor - positive breast cancers.

Not exact matches

In animal and cell culture studies, the drug inhibited growth both in estrogen - dependent breast cancer cells and in cells that had developed resistance to the anti-estrogen tamoxifen and / or to the aromatase inhibitors, two of the most widely used types of drugs to prevent and treat estrogen - dependent breast cancer.

«Never before has PTK6 inhibition been shown to inhibit growth and induce cell death of ER + breast cancer cells, including those resistant to standard treatments for this subtype such as tamoxifen,» said Hanna Irie, MD, PhD, Assistant Professor of Medicine (Hematology and Medical Oncology) and Oncological Sciences at The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, and senior author of the study.

Phthalates inhibit tamoxifen - induced apoptosis in MCF - 7 human breast cancer cells.

As a result, breast cancer cell growth is blocked One study in mice concluded that flaxseed inhibited the growth of human estrogen - dependent breast cancer, and strengthened the tumor - inhibitory effect of tamoxifen.

Multiple other studies with mice have shown that dietary flaxseed works with tamoxifen to inhibit breast tumor growth.

According to Lise Alschuler, author of the Definitive Guide To Cancer: An Integrative Approach to Prevention, Treatment, and Healing, studies on flax lignans demonstrate safety and efficacy in their use against breast cancer, «inhibiting the growth of human estrogen - dependent breast cancer cells in mice and strengthening the tumor - inhibitory effect of tamoxifen».