Sentences with phrase «targeted sequence alteration»
Targeted sequence alteration in the genomes of mammalian cells mediated by oligonucleotides
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Advances in genomic sequencing technologies have improved the ability to detect molecular aberrations with greater sensitivity and to identify genomic alterations that can be matched to targeted therapies.
Shown to work just 3 years ago, CRISPR consists of a an enzyme called a nuclease and a piece of RNA that homes in on a targeted DNA sequence, enabling the enzyme to introduce precisely targeted mutations, corrections to mutations, or other alterations.