Not exact matches
But the Doudna / Charpentier team, as they reported in a landmark paper published online by Science on 28 June 2012, at that point had only
used CRISPR to cut DNA in
test tube studies.
Because the findings clearly show that the positive
test -
tube and monkey
studies of PRO 2000 were misleading, researchers now know to
use more stringent requirements to deem a product worthy of human trials.
Although the experiment
used an older Ebola virus that differs from the strain now in West Africa, the researchers showed in a
test -
tube study that ZMapp also worked against the more recently isolated virus.
In their
study Loeken and her group, including Yichao Wu, Marta Viana, and Shoba Thirumangalathu,
used mice and cell lines to
test their hypothesis that AMPK might be stimulated in the embryo and that stimulation of AMPK was responsible for blocking Pax3 expression and causing neural
tube defects in response to high glucose.
Because scientists could
use the new stem cells to make any tissue in a
test tube, they might have an easier time
studying certain diseases and treatments.
Another
study that i latched onto was regarding the
use of ascorbic acid vs. citric acid in preserving the tea catechins» stability; this was however just by
test tube (in vitro), and not
tested on human subjects.
The
study was done
using an in vitro (i.e. «in glass» or
test -
tube) cell culture model of the small intestinal epithelium.
The
test tube study, which was the first of its kind to evaluate cinnamon leaf oil, found that the oil inhibited production of nitric oxide, a byproduct of inflammation that is sometimes
used as an indicator for levels of inflammation in the body.