Sentences with phrase «th17 cell plasticity»

High - fat diet consumption during pregnancy and the early post-natal period leads to decreased < i > α cell plasticity in the nonhuman primate.: High - fat diet causes decreased α cell plasticity.

To identify the molecular mechanisms of neural stem cell plasticity in adult zebrafish brain after various types of tissue damage or physiological stimulations

Furthermore, stem cells in bone marrow may form not just hematopoietic cells, but cardiac muscle cells, neural cells, and other types of cells; this is an example of stem - cell plasticity.

Molecular mechanisms of stem cell plasticity and regenerative neurogenesis in adult zebrafish brain

Cédric Maurange, 2nd Call 2010 Institute of Developmental Biology of Marseille - Luminy Neural stem cell plasticity in Drosophila [email protected] [phone]

Title: Cell plasticity in Caenorhabditis elegans: from induced to natural reprogramming Authors: Hajduskova M, Daniele T, Ahier A and Jarriault S Date: 2012 Publication Details: Genesis 50 (1): 1 - 17.

For example, adjuvant therapies that inhibit this type of cell plasticity may be a very effective way to keep metastasis at bay.»

Prior to joining ViaCyte, Dr. D'Amour performed pre-doctoral research with Dr. Fred Gage at The Salk Institute where he studied stem cell plasticity in neural stem cells.

Not exact matches

«In animal studies, exercise has been shown to specifically affect the hippocampus, significantly increasing the growth of new neurons and cell survival, enhancing memory and learning, and increasing molecules that are involved in the plasticity of the brain,» Chaddock said.

They found that exercise may help cognition by increasing blood and oxygen to the brain, increasing levels of norepinephrine, and endorphins to decrease stress and improve mood, and increasing growth factors that help create new nerve cells and support synaptic plasticity.

«There is still a long way to go before diabetes patients might be able to benefit from these findings, but the discovery that delta cells have a high degree of plasticity points to a hitherto unsuspected option for therapeutic intervention.»

According to Bean, study co-author Alexander Binshtok, a Harvard postdoctoral researcher in neural plasticity, is already at work eliminating capsaicin's negative effects by reversing the order of the injections: leading with QX - 314, quickly followed by capsaicin to shove it through the cell.

Dr. Monteggia's lab focuses on the molecular and cellular bases of neural plasticity, the fundamental property of nerve cells to alter their communication, as they pertains to neuropsychiatric disorders, as well as understanding the mechanisms underlying antidepressant efficacy.

Next, the team used other mouse models in which part of the lung was removed and single cell culture to study the plasticity of cell types during lung regrowth.

Moser demonstrated a number of changes in the strength of connections between nerve cells — a phenomenon called synaptic plasticity — in the hippocampus as rats stored information in their long - term memory.

One hypothesis is that RNA molecules encoding proteins necessary for plasticity are stored in cell compartments close to the synapses, poised to be translated into proteins when needed.

The work, which appears in the journal Cell, focuses on the regulation of «neuronal plasticity» — changes in neuronal structure — and its function in the brain.

Because these receptors are restricted to two distinct MSN populations, this postulate demands that synaptic plasticity be unidirectional in each cell type.

But there are also neural stem cells as well as early progenitors that have this plasticity in most of the other systems of the body.

Cellular plasticity is the ability of a cell to make different cell types.

The researchers concluded that in the early stages after stroke, improvements in voluntary movement can be attributed to a reduction in brain swelling because of the trauma and other spontaneous repairs, while later improvements result from «neuronal plasticity» — the reorganization or regeneration of nerve cells within the spinal cord in response to changes in the nerve network.

The single cell and the two cells resulting from it, have the highest level of cellular plasticity: They are totipotent, which means they can make a full organism, including the extra-embryonic placental tissue.

«Our results suggest that the location of the translational hotspot is a regulator of the simultaneous translation of multiple messenger RNAs in nerve cell dendrites and therefore synaptic plasticity,» says Sul.

These factors are proteins that encourage cell growth, plasticity and survival, and therefore play an essential role in controlling neuronal function.

Scientists have been attempting such a feat for years, refining their methods along the way, and the Irvine team finally saw success: the cells were integrated in the brain and caused large - scale rewiring, restoring the high - level plasticity of early development.

It is not yet known whether the proliferation of the transplanted cells accounts for the restored plasticity or if the new cells trigger plasticity in existing neurons.

The mTOR protein is part of a complex that carries out a multitude of functions within cells, including the formation of synapses — the connections between neurons — their maintenance and plasticity.

The mTOR protein is part of a complex that carries out a multitude of functions within cells, including the formation of synapses ---- the connections between neurons ---- their maintenance and plasticity.

Context, tissue plasticity, and cancer: are tumor stem cells also regulated by the microenvironment?

Using cell culture assays and genetically modified mice, we identified a number of signaling proteins that participate in muscle plasticity.

In thinking about what molecules on the surfaces of cells had both the plasticity and molecular complexity to explain developmental programs, I knew it had to be the glycans.

My research has focused on muscle plasticity: how cardiac and skeletal muscle cells sense and transduce signals from the environment to the genome, thereby altering their structural and metabolic capabilities to perform contractile work.

Professor Martin's research focuses on the cell biology of transcription - dependent forms of synaptic plasticity, particularly those underlying learning and memory.

When the researchers modeled the effects in mice, they found it strengthened the connections between neurons that make learning possible — what is known as synaptic plasticity — by increasing the action of a cell receptor critical to forming memories.

For the type I interferon (IFN) receptor (IFNAR) as a paradigm for functional plasticity, we have, within the first funding period, established single molecule imaging techniques for monitoring receptor assembly and dynamics in the plasma membrane of living cells.

We use the fission yeast, Schizosaccharomyces pombe, to study the dynamic changes and plasticity of gene expression programs as a function of cell proliferation, quiescence and ageing, and the effect of various genetic and environmental perturbations.

Moreover, some neuroblastoma cells exhibit plasticity and are able to shift between the NCC - like and noradrenergic identities.

The understanding of cell identity, heterogeneity and plasticity in neuroblastoma has strong implications with respect to the development of new therapeutic strategies to eradicate tumor cells in neuroblastoma patients.

Anna Huttenlocher, University of Wisconsin, USA Neutrophils in the Tumor Microenvironment Neutrophils, Wounds, and Cancer Progression Stefan Kaufmann, Max Planck Institute, Germany Pathology and immune reactivity: understanding multidimensionality in pulmonary tuberculosis Constitutive BAK activation as a determinant of drug sensitivity in malignant lymphohematopoietic cells Kathryn Moore, New York University, USA MicroRNA -33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis Lalita Ramakrishnan, University of Cambridge, UK Myeloid Growth Factors Promote Resistance to Mycobacterial Infection by Curtailing Granuloma Necrosis through Macrophage Replenishment Beth Stevens, Harvard University, USA Microglia: Dynamic Mediators of Synapse Development and Plasticity Do glia drive synaptic and cognitive impairment in disease?

They have the plasticity to differentiate in to mesenchymal and non-mesenchymal cell types alike, both in vitro and in vivo 5, 6, 7.

These findings suggest that regenerating organisms such as zebrafish could use special molecular programs to modulate the plasticity of the neural stem cells and enable restoration of compromised neural tissues.

Researchers have discovered a new form of synaptic plasticity, the changes to nerve cells in the brain that underlie learning and memory.

Stem cells have the plasticity to potentially differentiate into any type of tissue cells.

This behavioural plasticity allows all dividing cells to participate in tissue repair, making tissues resilient to injury.

Allogeneic cell transplantation enables the use of «younger» cells, from fetal origins (e.g., umbilical cord blood, placenta) or healthy donors, which are considered to be effective due to higher regenerative potential and plasticity.

Their work could pave the way for more effective prevention of heart attack and stroke in humans caused by atherosclerosis, in which artery walls thicken and suffer reduced plasticity due to an accumulation of white blood cells.

Therefore, histone marks represent an epigenetic marker or code that can be used by the cells to expand their plasticity and complexity.

Health and Medicine Reporter Research Aliquots brain plasticity cell and developmental biology Current Biology David Miller development neuroscience NIH NINDS Reporter Sept 18 2015 synapse

Title: «Hearts and bones»: the ups and downs of «plasticity» in stem cell biology Authors: Bonfanti P, Barrandon Y, Cossu G Date: 2012 Publication Details: EMBO MOlecular Medicine 2012 May 4 (5): 353 - 361

TAD dynamics displayed signs of elevated plasticity at later stages of reprogramming, as cells attain pluripotency