If shape plays a critical role in V. cholerae infection,
then cholera treatments could be developed that either impede the bacteria's ability to morph, or alter a patient's gut so that the bacteria can't infect it, said corresponding author Zemer Gitai, Princeton's Edwin Grant Conklin Professor of Biology and professor of molecular biology.
Not exact matches
Then, two weeks into that, we received our first
cholera case.
And
then I gave Adam syphillis,
cholera, typhus, leprosy, rabies, malaria, and tuberculosis all simultaneously, because I'm a real ass... and I needed a human vector for some of these historic diseases.
Back
then, it was indicated to treat «neuralgia, gout, rheumatism, tetanus, hydrophobia, epidemic
cholera, convulsions, chorea, hysteria, mental depression, delirium tremens, insanity, and uterine hemorrhage.»
The battle against
cholera,
then, is a microcosm of the larger, systematic problems that have made Haiti the poorest and most intractable nation in the Western Hemisphere.
Overwhelmed doctors — some of whom, Lantagne says, literally had no idea what
cholera was — began stacking patients two to a bed,
then on the floor.
As a result, dozens of passengers who arrived in Los Angeles, some of whom
then changed planes and flew on to Nevada and even as far as Japan, found that they had contracted
cholera.
The discovery not only helped prevent the further spread of the disease but also constituted a major medical breakthrough — until
then the scientific establishment had wrongly assumed that
cholera was transmitted by air, not water.
Indeed, when a flight from Buenos Aires to Los Angeles stopped in Lima in 1992, it picked up some seafood infected with the
cholera then making the rounds in Peru.
A typical visitor might find her way there via a Google search on «epidemiology» or «
cholera» and
then sample various versions of the outbreak map that Snow tinkered with over the years, or download a handful of PDF files that offer a comprehensive account of his public - health legacy.
And
then, using data collected by other scientists on three predator - prey pairs — mink - muskrat, gyrfalcon - rock ptarmigan and phage - Vibrio
cholerae — they show how their theory could explain unexpected population cycles.
For reasons no one quite understands,
cholera epidemics seem to follow the seasons, surging and
then receding in predictable patterns.
The researchers discovered the protein that allows the bacterium Vibrio
cholerae to morph into a corkscrew shape that likely helps it twist into — and
then escape — the protective mucus that lines the inside of the gut.
And he very carefully and very meticulously by hand drew maps and put dots of all the
cholera cases and
then looked at the wells.
And
then all of the cases of
cholera in that area suddenly dropped dramatically.
It is
then that Lyon pays tribute to the Virgin Mary for saving the city from a
cholera epidemic that hit Europe in 1823.
There was no compensation paid
then - the disruption was widely shared, everyone's toilet contributed to the
cholera problem, and everyone benefited from having it solved.