Sentences with phrase «therapeutic implications of»

The workshop will, in an interactive context, explore the therapeutic implications of the plenary.

The therapeutic implications of family cognitions and family constructs.

The therapeutic implications of ketone bodies: The effects of ketone bodies in pathological conditions: ketosis, ketogenic diet, redox states, insulin resistance, and mitochondrial metabolism.

The therapeutic implications of ketone bodies: the effects of ketone bodies in pathological conditions: ketosis, ketogenic diet, redox states, insulin resistance, and mitochondrial metabolism

Pal L, Berry A, Coraluzzi L, Kustan E, Danton C, Shaw J, Taylor H Therapeutic Implications of vitamin D and calcium in overweight women with polycystic ovary syndrome..

Diverse cellular functions and therapeutic implications of Poly (ADP - ribose) family members: promising targets in cancer therapy

And what are the therapeutic implications of such findings in aging people not exposed to this neurotoxin?

Consider the therapeutic implications of emerging data on evolving treatment paradigms for patients with hematologic tumors

«Next, we will explore the therapeutic implications of our discovery by repurposing available drugs that block these adenosine receptors and are well tolerated in humans.»

The therapeutic implications of the findings are far - reaching.

Not exact matches

The House Committee on Oversight and Government Reform's hearing featured a string of critics who rebuked Bresch for raising the price of a product with life - or - death implications, especially one that needs to be replaced almost every year and in a therapeutic space where Mylan has more than 90 % market share.

«The genetics of this cancer are very simple and our results have clear implications for therapeutic treatments for the disease.»

«The specific macromolecular complex investigated in this study has therapeutic implications not only for addiction, but also for Parkinson's disease and schizophrenia,» said Dr. Sergi Ferré, who led the team of scientists.

The discovery of 6 - OH - dopa has therapeutic implications for more than just breast and ovarian cancer — the diseases most widely associated with BRCA mutations.

Adds Matt Kaeberlein, a biologist who studies aging at the University of Washington, Seattle, «The therapeutic implications are profound if this mechanism holds true in people.»

Professor Fallon said: «This identification of an early stage cellular checkpoint that can act as a break on allergic responses has important implications for the development of new therapeutic approaches for asthma and other allergic diseases.»

Yet, for Kaileh, the most rewarding aspect of her research has been engaging in biomedical work that could have real therapeutic implications.

Dr. Dong said the findings have significant implications in the prevention and treatment of type 2 diabetes and could prove to be useful targets for modulation of insulin sensitivity and glucose homeostasis and as a target for therapeutic agents to increase liver function to prevent diabetes.

Clarification of delirium severity can indicate whether the therapeutic regime that the ICU clinicians have implemented is effective or not and can have implications for a patient's prognosis.

And though VR holds great potential, including for educational and therapeutic uses, Madary said manufacturers need to team up with scientists to investigate the long - term implications of the technology.

The question of whether people can harbor more than one character has important legal and therapeutic implications.

Dr Jaberzadeh said the technique had exciting implications for a whole host of conditions in which «enhancement of the brain excitability» has a therapeutic effect.

Many stem cell scientists who believe the ruling will discourage investment in the therapeutic applications of ES cell research reacted with dismay to the ruling, but the ultimate implications are far from clear.

The results of this study may have implications for physicians trying to decide on the best therapeutic options for their patients.

«This concept has significant therapeutic implications and will drive the development of new therapies because it implies that MS will produce significant disability if suffered for enough time in all patients,» says co-author Dr. Pablo Villoslada, Head of the IDIBAPS research group in Pathogenesis and new treatments in multiple sclerosis and coordinator of the study.

We suggest these observations will have therapeutic implications for skeletal myopathies and systemic diseases such as diabetes and obesity and for the aged population, in which reduced endurance impacts mortality and activities of daily living (57); as well as societal implications in terms of altering athletic performance.

This model, he said, could have important implications for the therapeutic use of stem cells to rejuvenate damaged tissues.

The findings, being presented as part of a poster presentation at the Annual Meeting of the American Association for Cancer Research (AACR) being held in Philadelphia this week, could have therapeutic implications specific to this rare form of the disease, say the authors.

With potential therapeutic implications, Stainier and a colleague also recently discovered that endothelial cells, which line the blood vessels, play a critical role in inducing the development, or proper differentiation, of red blood cells, the transporters of oxygen.

Azevedo - Pereira JM, Santos - Costa Q. [Chemokine receptors and its importance in the replication cycle of human immunodeficiency virus: clinical and therapeutic implications].

• Pharmacogenetics The unit offers population screening for a number of validated polymorphisms with pharmacogenetic implications, associated with positive or negative responses to therapeutic agents.

The understanding of cell identity, heterogeneity and plasticity in neuroblastoma has strong implications with respect to the development of new therapeutic strategies to eradicate tumor cells in neuroblastoma patients.

Dose and temporal pattern of estrogen exposure determines neuroprotective outcome in hippocampal neurons: therapeutic implications.

The results of the present study have shed unexpected light into the mechanisms of vascular Ang / Tie signalling that may help to answer a number of enigmatic questions in the Ang / Tie field and that may have implications for the therapeutic exploitation of Ang - Tie signalling, particularly in the context of tumour angiogenesis.

Inappropriate activation of the androgen receptor by nonsteroids: involvement of the Src kinase pathway and its therapeutic implications.

Angiogenesis revisited: role and (therapeutic) implications of endothelial metabolism Peter Carmeliet, University of Leuven

Our findings open the way to develop therapeutic strategies to remove lipofuscin from RPE cells, which may have implications for the treatment of age - related macular degeneration in which lipofuscin accumulation in cells is a causative factor.

While mutational burden has important implications for treatment with immunotherapy, the presence of specific driver mutations is also of major therapeutic relevance (Table 3).

Even if glcosepane's low tissue burden in rats means that cleaving it will not have dramatic rejuvenating effects in these animals (which is a reasonable prediction, but might be happily disproven in the event), its high prevalence in aging and diabetic human collagen, and its implication in the complications of diabetes, will make the mere demonstration of a candidate's ability to cleave glucosepane crosslinks in vivo a sufficient proof - of - concept to spur further work to move it down the therapeutic pipeline into human testing.

We still do not know whether certain DNA variations can result in the assembling and perpetuation of specific microbiota profiles, and this may bear important implications for the potential to treat common diseases through therapeutic modification of the gut flora.»

Our findings provide mechanistic underpinnings for the previous implication of Del - 1 as a candidate MS susceptibility gene and suggest that Del -1-centered therapeutic approaches may be beneficial in neuroinflammatory and demyelinating disorders.

«This has broad therapeutic implications as well,» says Lindquist, who also is a professor of biology at MIT.

«The profound protective effects of progranulin against both amyloid - beta deposits and cell toxicity have important therapeutic implications,» said senior author Li Gan, PhD, an associate investigator at Gladstone and associate professor of neurology at the University of California, San Francisco.

5) Saurabh K, Scherzer MT, Shah PP, Mims AS, Lockwood WW, Kraft AS, Beverly LJ (2014) The PIM family of oncoproteins: small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets.

Such a therapeutic platform has significant clinical implications for improving the treatment of metastatic breast carcinoma and other malignant solid tumors.

, Kraft AS, Beverly LJ (2014) The PIM family of oncoproteins: small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets.

In this review, dates fruits has medicinal value are summarized in terms of therapeutic implications in the various types of diseases through anti-oxidant, anti-cancerous and ant - diabetic character.

The decline of androgen levels in elderly men and its clinical and therapeutic implications.

Goulb LM, et al: Tetracyclines imibit comective tissue breakdown: new therapeutic implications for an old family of drugs.

Much of this research also has a one health implication designed to streamline drugs or therapies for human trials, decreasing the cost of drug approval while improving therapeutic options for dogs afflicted with cancer.