Sentences with phrase «through epigenetic alterations»
Through epigenetic alterations, our genomes retain something like a memory of the environmental signals received during the lifetimes of our parents, grandparents, great - grandparents, and perhaps even more distant ancestors.
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They also collected DNA to study epigenetics — changes in the activity of how a gene is expressed through environmental experiences, rather than alteration of the genetic code itself.
Understanding these pathways, and the identification of the key proteins that control the ability of cancer cells to reprogram their metabolism through biochemical, and epigenetic or genetic alterations that make them resistant to therapies, is of paramount importance for the design of more targeted and therefore less toxic therapies.