Sentences with phrase «tissue model system»

This procedure is important when using the MimEX ™ Tissue Model System from R&D Systems.

This distribution helps to maintain the health and rapid proliferation rate of adult epithelial stem cells using MimEX ™ Tissue Model Systems.

MimEX ™ Tissue Model Systems provide a robust system to generate accessible ex vivo 3 - D tissue from epithelial - derived organs.

MimEX ™ Tissue Models System provides a platform for the isolation, expansion, and differentiation of adult epithelial stem cells into 3 - D ex vivo organ tissue.

This video provides an overview of MimEX ™ Tissue Model Systems, a next - generation 3 - dimensional (3 - D) cell culture platform for the generation of ex vivo epithelial - derived organ tissue.

Consisting of optimized media and reagents, MimEX ™ Tissue Model Systems provides an alternative to current 3 - D cell culture modes, such as organoids, with the added benefit of...

Using Cultrex ® BME, MimEX ™ Tissue Models System provides a platform for the isolation, expansion, and differentiation of adult epithelial stem cells into 3 - D ex vivo organ tissue.

Not exact matches

«It's useful in modeling concepts in neuroscience to have a system that will yield a diverse range of behaviors for small changes of a control parameter, as this may help offer some insights about how the same neural tissue displays different responses,» Alonso said, whose research was funded by a fellowship from the Leon Levy Foundation.

Specifically, I am investigating how the cAMP / PKA signaling pathway affects collagen structure and deposition, using a hydrogel - based, three - dimensional culture system to create a model that is more physiologically relevant than one produced by standard two - dimensional tissue culture methods.

Using a mouse model of HSV - 1 as well as autopsied samples of human adult and fetal tissues, investigators from Dartmouth College's Geisel School of Medicine found that antibodies against HSV - 1 produced by adult women or female mice could travel to the nervous systems of their yet unborn babies, preventing the development and spread of infection during birth.

Scientists are taking medical imaging research and drug discovery to a new level by developing a molecular imaging system that combines several advanced technologies for all - in - one imaging of both tissue models and live subjects, say presenters at the 2015 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI).

In 2010, Radovitzky's group, working in concert with the Defense and Veterans Brain Injury Center, a part of the U.S. military health system, developed a highly sophisticated, image - based computational model of the human head that illustrates the ways in which pressurized air moves through its soft tissues.

The nerve cord in Drosophila has been used as a model system for over 30 years to understand how neuroblasts generate a highly complex but organized tissue.

Her lab is now developing a model system for Parkinson's disease that includes brain, liver, and gastrointestinal tissue, which she plans to use to investigate the hypothesis that bacteria found in the gut can influence the development of Parkinson's disease.

We have been using cell culture models and zebrafish as an assay to determine the effects of BMP on signaling, but we also want to be able to understand what the effect of the mutation is in the tissue and organ systems.

According to co-author Peter Ladurner, an assistant professor at the University of Innsbruck, the worm has many properties that make it a good model system: «M. lignano is small, has simple tissues and organs, is transparent, and has sexual reproduction.»

By using fruit fly as a model system, Minna Poukkula working at the Institute of Biotechnology, University of Helsinki, has found out how actin - rich protrusions contribute to cell migration in animal tissues.

Researchers at the University of California, Berkeley, in collaboration with scientists at the Gladstone Institutes, have developed a template for growing beating cardiac tissue from stem cells, creating a system that could serve as a model for early heart development and a drug - screening tool to make pregnancies safer.

The publication of the latest Canine genome build and annotation, CanFam3.1 provides an opportunity to enhance our understanding of gene regulation across tissues in the dog model system.

Anand hopes his brain model could be incorporated into the Microphysiological Systems program, a platform the Defense Advanced Research Projects Agency is developing by using engineered human tissue to mimic human physiological sSystems program, a platform the Defense Advanced Research Projects Agency is developing by using engineered human tissue to mimic human physiological systemssystems.

In the new study, published in PLOS Pathogens, scientists used an experimental system that models the mucosa and surrounding tissues.

Researchers from the Gladstone Institutes, in collaboration with scientists at UC Berkeley, have developed a template for growing beating cardiac tissue from stem cells, creating a system that could serve as a model for early heart development and a drug - screening tool to make pregnancies safer.

He uses the paradigm of nuclear hormone receptor activation / signaling and the contribution of this process to myeloid cell differentiation, function, and to diseases, involving these cells, such as atherosclerosis, tissue regeneration, metabolic, and various inflammatory disorders, as his model systems.

She is working, for example, on a model of liver function that fits hundreds of samples of 3 - D liver tissue into the pits of a multiwell plate and uses micropumps to circulate nutrients and oxygen through the system.

Toxicology and compound testing The zebrafish model system is ideal for testing biological effects on tissue homeostasis and organism development of substances and pollutants.

Weimin Li: Innovative 3D tissue matrix scaffold system for tumor modeling and drug screening

The authors note that the formation of each different organ bud type may require some fine tuning to optimize tissue self - organization, and further addition of neural cell types may be necessary, but this research may soon provide exciting model systems for the study of basic biology and pathology as well as providing appropriate replacement tissues for the treatment of many patients with no other viable options.

The compounds in PTC's research treat the underlying cause of the disorder and demonstrate increases in SMN levels in nervous system, muscles and other tissues in SMA models.

Our lab uses a variety of model systems, such as the nematode C. elegans, as well as in vitro culture systems, to address fundamental questions in cell cycle control during development and tissue formation.

Genetic approaches in mouse model systems combined with cell biological assays have allowed Professor Lukas Sommer to identify mechanisms regulating stem cell fates in the developing CNS and in neural crest - derived tissues.

7/16/2008 Improved Culture System for Hepatitis C Virus Infection A University of California, San Diego School of Medicine researcher has developed the first tissue culture of normal, human liver cells that can model infection with the Hepatitis C virus (HCV) and provide a realistic environment to evaluate possible... More...

The Livermore PK analysis showed that SiNPs were rapidly cleared from the circulatory system (the «central compartment» in PK models) and were distributed to various body tissues, where they persisted over the eight - week time course of the study, raising questions about the potential for bioaccumulation and associated long - term effects.

3D cell culture provides a biomimetic model of cell systems for many applications including cell / tissue models and constructs for basic / medical research, product testing, and regenerative medicine.

Topics covered include embryonic stem cells, pluripotency, germline stem cells, tissue - specific stem cells, stem cell differentiation, epigenetics, stem cell genomics and systems biology, genome reprogramming, cancer stem cells, stem cell niches, stem - cell - based disease models, nuclear transfer technology, bioengineering, drug discovery, in vivo imaging of stem cells, therapeutic applications, regenerative medicine, clinical and translational insights, stem cell research policies, ethical issues, and technical or resource - based innovations.

SAN FRANCISCO, CA — Researchers at the University of California, Berkeley, in collaboration with scientists at the Gladstone Institutes, have developed a template for growing beating cardiac tissue from stem cells, creating a system that could serve as a model for early heart development and a drug - screening tool to make pregnancies safer.

Development of a comprehensive system which can enrich hPSC - CMs will be ultimately useful for cell therapy for diseased hearts, human cardiac disease modeling, cardiac toxicity screening, and cardiac tissue engineering.

Having discovered a genetic «key» (called P - TEFb) that is important in both cancer cell growth and immune cell differentiation, they tested the drugs on a mouse model for uveitis, an incurable eye condition in which the immune system mistakenly attacks healthy tissue leading to inflammation of the uvea (the middle layer of the eye).

The rabbit has provided an excellent model system to simulate the response of human tissue to the radiation produced by surgical lasers.

RegenDbase — the Comparative Models of Regeneration Database — provides a systems - level view of genes across models of tissue regeneration to advance knowledge of regenerative biology and stem cell self - reModels of Regeneration Database — provides a systems - level view of genes across models of tissue regeneration to advance knowledge of regenerative biology and stem cell self - remodels of tissue regeneration to advance knowledge of regenerative biology and stem cell self - renewal.

These findings have identified an alternative source of replacement tissue for use in human retinal cellular therapies, and provide a new in vitro cellular model system in which to study RPE diseases affecting human patients.

She will discuss the Systems Biology approaches currently used to understand the Omics results from space flight model systems (rodent, fruit fly etc) in the context of tissue response (i.e. muscle, liver, other vital oSystems Biology approaches currently used to understand the Omics results from space flight model systems (rodent, fruit fly etc) in the context of tissue response (i.e. muscle, liver, other vital osystems (rodent, fruit fly etc) in the context of tissue response (i.e. muscle, liver, other vital organs).

The endocannabinoid system regulates energy homeostasis through G protein — coupled cannabinoid - 1 receptors5, 6 located in the central nervous system and in various peripheral tissues, including adipose tissue, muscle, the gastrointestinal tract, and the liver.7 While peripheral cannabinoid - 1 receptor activation decreases adiponectin production in adipocytes, 8 central cannabinoid - 1 receptor activation in preclinical studies stimulates eating, decreases muscle, and stimulates hepatic and adipose tissue lipogenic pathways in animal models of obesity.9 In genetic and diet - induced obesity, rimonabant, a selective cannabinoid - 1 receptor blocker, reduces overactivation of the central8, 10 and peripheral11, 12 endocannabinoid system8, 10,13 and prevents weight gain and associated metabolic disorders, thus revealing a novel strategy for the treatment of obesity and related cardiometabolic disorders.

This is because the standard health care model does not screen for autoimmunity such as Hashimoto's — a disorder than occurs when your immune system attacks and destroys your own tissue.

Providing further connective tissue between felt and the bees, this idea of the open system serves equally as a model for our own collectivity.