Mouse Pancreas
Tissue Slice Culture Facilitates Long - Term Studies of Exocrine and Endocrine Cell Physiology in situ.
In particular, we use 2D and 3D in vitro cell cultures;
tissue slices cultured ex vivo; and transgenic mouse models.
Not exact matches
A
tissue slice, a tumor biopsy, or a sample of a bacterial
culture yields a sequence representing the average of all of the cells within it, even though researchers know there can be tremendous variation between those cells.
protected animals»); studies on in vitro systems (whole perfused organs,
tissue slices, cell and
tissue cultures, and subcellular fractions); and human studies (including estimations of occupational and environmental exposure, postmarketing surveillance, epidemiology, and the ethical and strictly controlled use of human volunteers).
In the current study, lead authors David V. Hansen, PhD, a postdoctoral fellow, and Jan H. Lui, a graduate student in the Kriegstein lab, examined the OSVZ, using new labeling and tracking techniques to follow individual cells and their progeny over time in
cultured tissue slices from fetal cortex
tissue that had been donated for research.
In addition to
cultured cells, Ts1 - coupled nanoparticles were tested on complex brain
tissue using thin
slices of mouse hippocampus.
To address these different topics we are developing relevant animal models that will be used in combination with primary neuronal
cultures, rodent brain
slices, and brain
tissues.
The Metabolomics & Proteomics Technology Unit will offer localizomics approaches based on MS Imaging on
tissue / organs
slices (or on in - vitro cell
cultures), either in targeted MS (i.e. drug and metabolites distribution) or in untargeted high resolution (HR) MS (metabolite profiling).
Users can provide frozen
slices of
tissue, entire frozen
tissue sample ready to be
sliced, or
cultures of cells.
The cellular mechanisms underlying this bursting behavior have been studied in vitro, using either acute
slices of the adult hypothalamus, or organotypic
cultures of neonatal hypothalamic
tissue.