Sentences with phrase «trabecular meshwork cells»

Our lab has recently shown that endogenous TGF - Î ² 2 expression can be markedly and significantly attenuated in human trabecular meshwork cells and porcine anterior segments using the compound XJB -5-131, a novel antioxidant that targets a cell's mitochondria.

The authors say that it's possible that the new trabecular meshwork cells generated from the stem cell treatment could eventually succumb to the same mechanisms that caused the fluid buildup in the first place, but further research is needed in that area.

TIGR is made by the eye's trabecular meshwork cells, which help regulate eye pressure by controlling the drainage of fluid from the eye as new fluid is produced.

Now, they are also are looking at the impact on the trabecular meshwork cells» ability to take up aqueous humor and deliver it back to the circulation.

The additional insight will help answer questions like whether trabecular meshwork cells become stiff and less capable of making the pores that let fluid come onboard for their endless transport task as Liu suspects.

He's also looking at the impact on the ability of trabecular meshwork cells to make and send out fluid - filled pockets called exosomes that may enable the cells to communicate.

Not exact matches

Its impact appears to reduce the ability of the cells in the eye's trabecular meshwork to continually move the clear aqueous humor out of the front of the eye and dump it into the body's general circulation, said Liu, corresponding author of the study in the journal Investigative Ophthalmology & Visual Science.

Other data obtained in this report (BrdU nitroblue tetrazolium staining by alkaline phosphatase and fluorescence due to fluorescein) would further suggest that putative stem cells are located in the posterior limbus between the peripheral endothelium and the trabecular meshwork.

The area of the trabecular meshwork and its surrounding posterior limbus in the human, however, showed considerable fluorescence indicative of cell division (Figure 6B).

Conclusions: It is suggested stem - like cells may be sequestered in a niche at the junctional region where the corneal endothelial cells and the trabecular meshwork come together.

However, we have found a fluorescent marker for nestin, a neural crest stem cell marker, in the posterior limbal region of the human anterior segment in the vicinity of both the trabecular meshwork and Schwalbe's line (unpublished).

In the lamina cribrosa, like the trabecular meshwork we hypothesize that exosomes participate in the turnover of extracellular matrix and homeostatic signaling with cell neighbors, particularly in response to elevations in intraocular pressure / pulsations.

RPB investigators have found that the normally spongy cells of the trabecular meshwork (TM) might be hardened by calcification in the eyes of people with glaucoma.