Sentences with phrase «transcription factors play»

Two MAPK cascades, NPR1, and TGA transcription factors play a role in Pto - mediated disease resistance in tomato

LLM - Domain B - GATA Transcription Factors Play Multifaceted Roles in Controlling Greening in Arabidopsis

Transcription factors play a pivotal role in many illnesses, including cancer as well as many hereditary diseases.

All of the mice produced normal amounts of SOX2 during development, when the transcription factor plays a critical role in the genesis of embryonic and neural stem cells.

Not exact matches

The scientists demonstrated the fact that the transcription factor MTF1 plays a central role in this connection using an experiment on mice suffering from epilepsy.

Some transcription factors already have been identified as playing a role in melanoma development.

The investigators focused on studying the activity of AHR, a transcription factor that is known to play a key role in regulating inflammatory and immune responses, and the effects of two AHR ligands (ITE and FICZ).

These include a family of signaling molecules called protocaderins, which regulate neuronal development and short - range interactions between neurons, and a family of transcription factors called zinc fingers, which are mainly expressed in embryonic and nervous tissues and are thought to play roles in brain development.

The transcription factor Gcn4 is conserved in over 50 different organisms, including mammals, and it likely play a significant role in the aging of these organisms as well.

Whitehead Institute researchers have determined that the transcription factor Nanog, which plays a critical role in the self - renewal of embryonic stem cells, is expressed in a manner similar to other pluripotency markers.

«There is emerging evidence that the FOXO transcription factor family plays a critical role in metabolic, antioxidant, and cell death responses in the liver.

Since all four of the genes could be regulated by a common transcription factor, peroxisome proliferator - activated receptors, it was supposed that the transcription factor might play an important role in carotenoid accumulation [33].

β - catenin, a transcription factor, has been known to crosstalk with several developmental pathways [28] and is reported to play a role in DNA damage repair [29, 30].

The cellular transcription factor NF - kB consists of two DNA - binding subunits of 50K and 65K and is believed to play an important role in stimulating transcriptional activation of HIV - 1 in latently infected T - cells

The bromodomain containing protein 9 (BRD9) has been reported as a component of the switch / sucrose non-fermentable (SWI / SNF) brahma - related gene 1 - associated factor (BAF) complex, which plays a key role in chromatin remodelling and transcription control [1] although the precise biological role is unknown.

Here, we have shown for the first time that the unphosphorylated STAT2 could play an important role in RIG - G gene expression by interacting with IRF - 9, further reinforcing the idea that STAT proteins could function as transcription factors in the absence of tyrosine phosphorylation.

In response to cellular stress such as DNA damage, oncogene activation, transcriptional inhibition, and hypoxia, tumor suppressor p53 is activated and expressed, and acts as a transcription factor to induce its target genes [1], thereby playing a central role in the regulation of DNA repair, cell cycle, apoptosis, senescence, and angiogenesis [2 - 4].

Other gene families that were dramatically expanded in the octopus include zinc finger transcription factors, which are mainly expressed in embryonic and nervous tissues and are thought to play roles in development.

Curcumin inhibits activation of the transcription factor NF - kB, [5] which plays an important part in the regulation of the immune response to infection.