«Our data are a strong proof of principle and the first to show that inhibiting fibronectin polymerization preserves heart function, reduces left ventricle remodeling and limits formation of fibrotic connective tissue,» said lead investigator of the study and director of translational research in the Heart Institute and the Center for
Translational Fibrosis Research.
Not exact matches
In the Netherlands, based on
research reported in 2016 in Science
Translational Medicine, Clevers and colleagues are already using personalized gut organoids, derived from rectal biopsies, to test whether cystic
fibrosis patients will benefit from available drugs.
Together with the Director of the Institute of
Translational Immunology, Professor Detlef Schuppan, Schattenberg is leading the LIFT - off (Lifestyle Intervention to prevent and improve hepatic
fibrosis in non-alcoholic fatty liver disease)
research initiative.
Using
translational research methods, the DZL seeks to jointly develop new approaches for the prevention, diagnosis and therapy of serious lung diseases including asthma, chronic obstructive pulmonary disease (COPD), cystic
fibrosis, diffuse parenchymal lung disease (DPLD), endstage lung disease, lung cancer, pneumonia and acute lung injury, and pulmonary hypertension.