Sentences with phrase «treating a human disease with»

Treating a human disease with aptamers is still «a leap, but in principle we can do this,» says Smith.

Not exact matches

There have been dramatic results from human trials in treating Crohn's disease, with 95 % of participants experiencing significant improvement in symptoms.

These findings allowed researchers to create a chimera virus: a mouse virus with a human viral gene that can be used to test molecules that inhibit human LANA protein in an animal model of disease, treating not only human herpes virus infection but also its associated cancers.

Building the knowledge base requires humans to teach computers key concepts from curated articles; with modest online training, anyone who reads English can scan research papers for key terms — names of genes, proteins, diseases, and drugs — and use online marking tools to document relationships between them (for example, drug X treats disease Y).

The survey, described today in a Policy Forum published by Science, randomly presented people with different vignettes that described genome editing being used in germline or somatic cells to either treat disease or enhance a human with, say, a gene linked to higher IQ or eye color.

A recent study published in Annals of Neurology reports that healthy human tissue grafted to the brains of patients with Huntington's disease in the hopes of treating the neurological disorder also developed signs of the illness, several years after the graft.

Additionally, work in a mouse model revealed similar cells, indicating that the progenitors are conserved from mouse to human, and therefore, they must be «important cells with promising potential for cell therapy in treating liver disease,» explained Dr. Gouon - Evans.

«This finding suggests that one could treat severe flu of childhood with interferon, which is commercially available,» says Casanova, who is professor and head of the St. Giles Laboratory of Human Genetics of Infectious Disease at Rockefeller, as well as a Howard Hughes Medical Institute investigator.

By pairing a receptor that targets neurons with a molecule that degrades the main component of Alzheimer's plaques, the biologists were able to substantially dissolve these plaques in mice brains and human brain tissue, offering a potential mechanism for treating the debilitating disease, as well as other conditions that involve either the brain or the eyes.

If these results translate to humans, we may be able to treat children with FOP early in life, before the disease progresses.»

Subsequent transplant of millions of human T - ALL cells into normal mice that were then treated with an anti-CXCR4 drug induced remission within two weeks, with diseased spleen and bone marrow tissue nearly returning to normal.

They subsequently treated worms and human cells with Huntington's disease with drugs that prevented the cell from sweeping up and storing the lipid, called ceramide, and saw the same protective effect.

«Once we've shown that this can safely be used in human patients with pulmonary hypertension — and we've got a clinical trial in progress right now — we'll be able to conduct studies of inhaled NO delivered in ambulatory settings, including patients» homes, to treat chronic pulmonary hypertension, right - sided heart failure and chronic obstructive pulmonary disease.»

«It's a bit like human disease but in plants, to understand the pathogen and its interaction with the plant allows to develop a functional cure to treat the affected plants» emphasizes the specialist in plant genomics.

Loke also mentions that colitis plagues many juvenile monkeys in primate research centers and that he has received a pilot grant to treat diseased monkeys with human whipworm, an as - yet - unpublished experiment that is already returning promising results.

On the basis of those results, at least one company is attempting to replicate the effect in humans using blood plasma from healthy young people to treat patients with Alzheimer's disease.

Jiang estimates that human clinical trials could begin within a decade: «At first, the cells could be used to treat diseases with single missing or malfunctioning cell types, like hemophilia, diabetes, Parkinson's disease, and muscular dystrophy.

A study coming out in Science Translational Medicine and led by University of Pennsylvania School of Veterinary Medicine researchers has shown that cats with NPC — which mirrors the human version of the disease — show vast improvements when treated with a compound called cyclodextrin.

The team at UF's Powell Center for Rare Disease Research and Therapy conducted the first in - human study of gene therapy to treat respiratory dysfunction in patients with infantile onset Pompe.

«Stem cell biology has become one of the most exciting and promising areas of research, with real impact on how we treat human disease,» said Gladstone President R. Sanders Williams, MD. «With its meetings and journals, ISSCR has developed a significant role in communicating and promoting groundbreaking advances in the fiwith real impact on how we treat human disease,» said Gladstone President R. Sanders Williams, MD. «With its meetings and journals, ISSCR has developed a significant role in communicating and promoting groundbreaking advances in the fiWith its meetings and journals, ISSCR has developed a significant role in communicating and promoting groundbreaking advances in the field.

This webinar will discuss the promise CRISPR / Cas9 has for rodent studies along with strategies for developing better models to understand and treat human disease.

With advanced technology based on this discovery, scientists can now edit the genomes of human cells to learn what causes intractable diseases — and find new ways to treat or cure them.

The mission of deCODE genetics is to use human genetics and genomics to acquire new knowledge about health and disease, and work with pharmaceutical companies and healthcare providers to develop novel methods to identify, treat and prevent diseases.

In recent years, researchers have developed so - called «senolytic» drugs that wipe out senescent cells in aging mice and mouse models of age - related disease, exploiting the high dependence of these cells on specific biochemical survival pathways.9, 10 In these studies, senolytic drugs have restored exercise capacity9 and formation of new blood and immune precursor cells11 in aging mice to near youthful norms, and prevented or treated mouse models of diseases of aging like osteoarthritis, 12 fibrotic lung disease, 13 hair loss, 14 atherosclerosis, 15,16 and age - related diseases of the heart itself.9 UNITY Biotechnology is leading a growing charge toward the clinic, with human clinical trials expected to begin in 2019.

ANN ARBOR, Mich — By combining engineered polymeric materials known as hydrogels with complex intestinal tissue known as organoids — made from human pluripotent stem cells — researchers have taken an important step toward creating a new technology for controlling the growth of these organoids and using them for treating wounds in the gut that can be caused by disorders such as inflammatory bowel disease (IBD).

Our company's mission is to improve human health by providing researchers and clinicians with the core technologies to understand, prevent, diagnose, and treat diseases and conditions.

With systems biology, we will learn how all of the different aspects of human health (diet, genetics and environment) affect these diseases and how to treat each individual patient with personalized medicWith systems biology, we will learn how all of the different aspects of human health (diet, genetics and environment) affect these diseases and how to treat each individual patient with personalized medicwith personalized medicine.

Stem cells have the capacity to differentiate into any of the different tissues making up the human body, thus holding the promise of treating or curing diseases such as multiple sclerosis or spinal - cord injury by replacing diseased cells with healthy cells.

A clinical trial is a research investigation when a new treatment is first given to humans, with or without a disease, to establish if the drug is safe and effective at treating the disease.

Treating human apoE4 neurons with a structure corrector eliminated the signs of Alzheimer's disease, restored normal function to the cells, and improved cell survival.

I think we all agree that we over treat prostate cancer in this country compared to what you see in Europe with similar outcomes and so but I think this is where the human or the Cancer Genome Project or at least better biomarkers for looking at mutations that we already know occur in these diseases I think hopefully within the next few years every single patient who is diagnosed with prostate cancer those biopsies will be characterized and then the patients followed, hopefully watchful waiting and we'll ultimately get a correlation between what mutational events predict a rather dormant disease as opposed to a very aggressive disease.

She joined the Pillai lab as a post-doctoral research fellow in 2016 and continues to enjoy her work both treating patients with primary immunodeficiency in the clinic and studying the bridging gap between human primary immunodeficiency disorders and the development of autoimmune disease pathology in the lab.

Vasculata ™ 2018 will be an intense 3 1/2 day course introducing the basics of cardiovascular biology and cardiovascular disease with an emphasis on new approaches to treating the most common causes of human disease in our society, based on cutting - edge research in the field.

«The doctors of the future will no longer treat the human frame with drugs, but rather will cure and prevent disease with nutrition.»

Because of these immune - enhancing effects, medicinal mushrooms have been used with good effect in veterinary and human medicine for treating viral diseases, recurrent bacterial infections and even cancer.

Dogs that are diagnosed with CCD may also be prescribed a medication known as Anipryl, which is also used to treat Parkinson's disease in humans.

Today, as with most things utilized in human medicine, lasers have eventually worked their way into veterinary practice to treat a variety of disease processes in small animals.

Drugs with similar effects to neostigmine, rivastigmine (Exelon patch), which is used to treat human Alzheimer's disease and a similar drug, Donepezil (Aricept) also inhibit (lower) cholinesterase levels.

Corticosteroids Glucocorticoids have been used to treat humans with bronchial disease for over 50 years.

Her goal in treating neurological diseases is to improve the quality of life of her patients, balancing the diagnostics and therapy she recommends with the comfort of her patients and their human counterparts.

Many of you may be familiar with clinical trials used in treating human disease.

Just as in humans, a pet with cancer typically needs the help of an oncologist to help diagnose and treat the disease.

Furthermore, if the genetic traits responsible for this disease in dogs are shared with human patients, precision medicine can be used to help develop targeted therapies to treat this life - threatening disease.

Job Description: • Represents the Kansas City Pet Project in a professional, polite and enthusiastic manner • Assists the veterinarians on a daily basis with preparing surgery patients, health assessments, and treatments of animals • Assist in medical rounds with Shelter Veterinarians or identifying animals that need to be seen by a Shelter Veterinarian • Administer medications to both cats and dogs in accordance with veterinarian's prescribed doses and ensure all treatment protocols prescribed for sick / injured animals are performed timely, safely, and humanely • Responsible for following best practices for sanitation protocols in all veterinary clinic and isolation areas to reduce / eliminate disease transmission • Input all medical notes, health assessments, vaccinations, surgeries, treatments, etc., into PetPoint • Provides support for other departments, such as Intake, Foster, Placement & Transport, or Adoptions by assisting as needed for vaccinations, deworming, blood draws, etc. • Prepares and sanitizes surgical instruments / packs each day to ensure packs are ready for use the following day • Assists with discharging animals to the public post-surgery or following up with sick pet appointments, explaining any medical issues, medications, after care instructions, etc. • Ensures adequate medical supplies and medications are available and reports any shortages to Vet Clinic Manager • Enforces and maintain KCPP safety and cleanliness, and all health and security rules and procedures • Follows disease prevention procedures and completes cleaning of veterinary clinic areas daily and ongoing throughout the day to decrease biological risks to humans and other animals • Care, feed, and safely handle animals to avoid injury to persons / animals • Properly store and maintain inventory of medical supplies, including Schedule II narcotics • Performs laboratory analysis techniques to assist Shelter Veterinarians • Reads, understand, interpret, and apply department policies and procedures • Prepares reports and other written materials in a logical, concise, and accurate manner • Functions calmly in situations that require a high degree of sensitivity, tact, and diplomacy • Communicates effectively with a variety of individuals representing diverse cultures and backgrounds and function calmly in all situations which require a high degree of sensitivity, tact and diplomacy • Treats employees, representatives of outside agencies, volunteers, and members of the public with courtesy and respect • Provides prompt, efficient and responsive service for all phone calls forwarded to the Vet Clinic.

Trials with drugs used to treat Parkinson's disease in humans have been shown to be useful in some dogs for selected behaviors.

The dog has already played an important role in emerging therapies for inherited blindness in humans and similarities in disease phenotype and eye structure and function between dog and man, together with the increasingly sophisticated genetic tools that are available for the dog, mean that the dog is likely to play an ever increasing role in both our understanding of the normal functioning of the eye and in our ability to treat inherited eye disorders.

In humans, this is essentially a surgical disease with surgery being a treatment of choice however due to the limitations in the veterinary field as mentioned above, medical management of congestive heart failure is still the mainstay of treating the condition in dogs.

Some versions of human medications have received approval by the Food and Drug Administration for specific mental - health uses in pets, including the antidepressant clomipramine (Clomicalm) for separation anxiety in dogs, the sedative dexmedetomidine (Sileo) for dogs with noise - aversion problems, and selegiline (Anipryl), a drug often used to treat Parkinson's disease in humans, for canine cognitive dysfunction.

Remember that the disease is not directly transmissible to humans from dogs, and it can be treated with antibiotics if caught early.