Sentences with phrase «treatment study which»

Not exact matches

Lilly faced a devastating clinical setback last year with a late - stage failure for its experimental Alzheimer's treatment, the studies for which cost the company hundreds of millions of dollars.

Furthermore, an early - stage study pumping up the dose of its hemophilia A treatment — which aims to be a one - time therapy for the rare blood clotting - related disease — appeared to hit its targets without serious side effects.

Which is a shame, because according to at least one recent study, there are actually three distinct types of burnout that demand three different types of treatment.

Speaking of checkpoint inhibitor drugs... Merck's star cancer immunotherapy treatment Keytruda is facing some troubling clinical trial incidents which have now compelled the Food and Drug Administration (FDA) to halt three studies of the drug in multiple myeloma, a rare blood cancer, after a number of patient deaths.

Private hospitals are typically the best equipped, with state - of - the art technology and doctors that have studied in the world's best medical universities — many of them speak English and are well acquainted with the newest diagnostic and treatment procedures... some of which may not yet be available in the U.S., for example.

That's striking because the treatment is part of a class called CETP medicines which haven't proven particularly successful in previous studies.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Chicago, GenomeWeb — A new study by researchers from Memorial Sloan Kettering Cancer Center has demonstrated the predictive power of an AR - V7 protein expression test using Epic Sciences» non-EPCAM-based circulating tumor cell detection platform, which could help guide treatment decisions for men with metastatic castration - resistant prostate cancer.

According to one study, this exotic superfood contains various bioactive compounds which contribute to the treatment of inflammatory conditions.

The most important limitation to understand is that PRP therapy has really only shown to be effective in research studies which look at the treatment of chronic tendon injuries (tendons connect muscles to bone) such as tennis elbow (irritation of tendons about the elbow).

As a result, Dr. Meehan argues that «the term mild traumatic brain injury should not be used interchangeably with concussion,» as suggested by the authors of a 2010 Canadian study, 2 which found that how a brain injury was labeled made a difference when it came to treatment, and suggested that, to encourage full reporting of head injuries in sports and to allow adequate management and recovery time, MTBI be used in its place.

She is a Director of the Selective Mutism Research Institute (SMRI), which is a foundation started to study her theories and treatment methodologies on Selective Mutism.

For the purposes of this economic evaluation, the forms were initially used in a related study funded by the National Institute of Health Research (NIHR) research for patient benefit programme «assessing the impact of a new birth centre on choice and outcome of maternity care in an inner city area,» which will be reported in full elsewhere, comparing the costs of care in a free standing midwifery unit with care in an obstetric unit in the same trust.16 The data collected included details of staffing levels, treatments, surgeries, diagnostic imaging tests, scans, drugs, and other resource inputs associated with each stage of the pathway through intrapartum and after birth care.

There have not been any studies (meta - analysis which are the ones used to support new treatments, etc) to support waiting longer.

Jungheim's study examined data from 1,572 women who sought IVF treatment from 2001 to 2010 at Washington University's Fertility and Reproductive Medicine Center, which serves women in Missouri and Illinois.

We examined plots visually to see whether there was any evidence of asymmetry that might suggest different treatment effects in smaller studies, which may indicate publication bias (Harbord 2006).

A sensitivity analysis omitting the cluster - randomised study (Ochola 2013) for which a design effect could not be calculated demonstrated a similar positive treatment effect (average RR 0.80, 95 % CI 0.71 to 0.89).

Constantinides proposed an addition to PlanNYC requiring that at least 20 percent of new constructions be carbon neutral by 2030 and a study of the Bowery Bay Wastewater Treatment Plant in Astoria to see if it could be into a park, similar to Riverbank State Park, which is built over a sewage treatment facility on the EaTreatment Plant in Astoria to see if it could be into a park, similar to Riverbank State Park, which is built over a sewage treatment facility on the Eatreatment facility on the East River.

The next step was to search the scientific literature to find out which academic groups were studying similar approaches to treatment for the same indications.

One way out of this dilemma, Daviglus notes, is to design a study in which patients suffering from hypertension get treatment, and doctors analyze the results based on how well the patients» blood pressure was controlled.

Those opinions are backed up by easily accessible evidence — doctors can click on the recommended treatment and see which medical studies support it.

The treatment group showed notable changes in the ability to identify and remember faces, which was corroborated by changes in brain patterns that arise when study participants saw a familiar face.

A clinical study will now be conducted of the new treatment, which has been developed in a collaboration between Chalmers University of Technology, Sahlgrenska University Hospital, the University of Gothenburg and Integrum.

Eighteen out of a projected 21 patients in Mithoefer's study have already been treated, and in many cases just two sessions dramatically diminished symptoms, which is remarkable because PTSD in this group of subjects has been resistant to other types of treatment.

In a study featured in the December issue of The Journal of Nuclear Medicine, Australian researchers demonstrate that PET scans can identify which of these prostate cancer patients would benefit from salvage radiation treatment (SRT).

Three Swedish hospitals and other European clinics will cooperate during the study which will target patients with conditions resembling the one in the case study — that is, people who suffer from phantom pain and who have not responded to other currently available treatments.

Results of the study, which ultimately included 146 men of whom 99 received SRT, show an overall treatment response after SRT of 72 percent.

Further studies and environmental monitoring could help identify the most harmful pollutants, which ones should be targeted for reduction in gasoline formulations and in optimization of engines and exhaust treatment technologies, the researchers conclude.

Researchers of the report, which is published in the June issue of Annals of Allergy, Asthma & Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI), examined 14 previously published studies to determine the effectiveness of yoga in the treatment of asthma.

Cao hopes the study, which was funded in part by the National Institute of Mental Health (NIMH), will pioneer future research on details within the hippocampus as a marker for precise diagnosis and positive treatment response of bipolar disorder.

Yang said the study not only indicated which genes are affected by traumatic brain injury and linked to serious disease, but also might point to the genes that govern metabolism, cell communication and inflammation — which might make them the best targets for new treatments for brain disorders.

As data on proton treatments continued to dribble in, it was hard for Zietman to accept the implications of his own studies, which tracked patients» progress.

The study also suggests that targeting the machinery that makes cells mobile, rather than targeting the tissue - clearing process — which has been tested in patients but has not been very effective — may be a better treatment strategy to stop cancers from spreading.

According to the charity SignHealth, which commissioned the work, the study «revealed shocking inequality in treatment, which means that some Deaf people are at risk of reduced life expectancy.»

For one thing, they point out, acupuncture studies are extremely difficult to double - blind — a methodological approach in which neither the researchers nor patients know who is receiving the treatment under investigation and who is receiving the placebo or sham.

Unlike «big data» genetic studies, which have loosely linked hundreds of genetic changes to schizophrenia but can not explain varying symptoms, the new study revealed distinct disease versions that may affect large slices of patients and enable precision treatment design, say the authors.

In a trio of studies to be presented at the 57th American Society of Hematology (ASH) Annual Meeting and Exposition in Orlando, investigators at Dana - Farber Cancer Institute will present the results of clinical trials showing that new drug combinations can significantly extend the time in which multiple myeloma is kept in check in patients with relapsed or treatment - resistant forms of the disease.

In this maximum - security prison, left unidentified for the study to protect the confidentiality of officers and inmates, officers received training to identify symptoms of mental illness, which, in turn, led to better security, safety and humane treatment of potentially volatile inmates.

The new drugs offer the hope of treatment to perhaps thousands of HIV patients who have stopped responding to other medications, says William Towner, medical director of the Kaiser Permanente HIV / AIDS research trials program and member of the study team, which reported its findings online today in The Lancet.

Two of his studies influenced 2009 treatment guidelines from the European Society of Cardiology, which recommended the use of β - blockers in «patients undergoing surgery that doesn't directly involve the heart.»

Recent studies have shown that there is no long - term risk of breast cancer from IVF, which requires women to undergo the same hormone treatment as egg donors.

The study could also lead to better treatment for diabetic retinopathy, which currently requires multiple, invasive procedures that aren't always effective in the long term.

Scope of the problem A National Institute of Mental Health (NIMH) study released this spring shows that 14 percent of patients with drug - resistant major depressive disorder experience a remission of symptoms after rTMS treatment compared with a control group, which reported a 5 percent rate of remission.

The bookended pre - and post-transplant treatments, which have been tested separately in other studies, already had promising track records in controlling cancer and preventing severe GVHD.

The REACT (Randomized Evaluation of an Algorithm for Crohn's Treatment) study, led by Robarts Clinical Trials at Western University (London, Canada) provides valuable new insights for community gastroenterologists which should benefit patients.

If the findings can be replicated in larger studies, it might be possible for doctors to identify which people will later develop schizophrenia, and offer them preventative treatments, he says.

These are some of the findings of a recent study published in the journal Psychiatric Services, which reported significant racial - ethnic differences in diagnosis and treatment of psychiatric conditions across 11 private, not - for - profit U.S. healthcare delivery systems.

Another problem is that modeling studies, like this one, are inherently less powerful than other kinds of medical research: randomized clinical trials, the gold standard in medical research, in which patients are randomly assigned different treatments or no treatment; case - control studies, which compare patients who have a condition with those who do not; or cohort studies, which determine the risk of contracting a disease by studying a group of people with similar demographics.

Although the trial first received the go - ahead in January last year, it was put on hold the following August by the US Food and Drug Administration, which demanded further evidence that the treatment wouldn't cause cysts like those seen in some animal studies.

«Of mice and disease: Antibiotic - resistant bacteria discovered in NYC house mice: A study of mice collected from apartment buildings reveals they carry several disease - causing pathogens, some of which may be resistant to treatments.»