Sentences with phrase «treg cells in the immune system»

Not exact matches

If there are insufficient Treg cells or if their function is impaired, the self - regulatory function of the immune system will be reduced, possibly resulting in allergies.

«Now that we know Myb has a defining role in the immune system, we are seeking to understand exactly how Myb gives Treg cells the authority to carry out their duty,» Professor Nutt said.

«Our studies imply that the change of oxygen levels in different tissues can be sensed by Treg cells and that this process is critically important for maintaining the correct balance between activation and suppression of the immune system,» says Liu.

Regulatory T cells (or «Tregs» for short) play a central role in the human immune system: They guide all of the other immune cells and make sure they are tolerant of the body's own cells and harmless foreign substances.

At the same time, the drugs can spark a reduction in immune system cells known as T regulatory cells (Tregs), which usually tamp down the immune response to disease or infection.

Because Tregs act to keep the immune system in check, they can inadvertently blunt the ability of immune cells to restrain or eliminate tumors.

A disparity between these cell types, when there are too many Th17 and not enough Tregs, can lead to a hyperactive immune system, resulting in inflammation, tissue damage, and autoimmune disease.

In the immune system, two kinds of T cells strike a delicate balance — T helper cells (Th17) activate the immune system, protecting against infections and cancers, while regulatory T cells (Tregs) suppress the system, keeping it in checIn the immune system, two kinds of T cells strike a delicate balance — T helper cells (Th17) activate the immune system, protecting against infections and cancers, while regulatory T cells (Tregs) suppress the system, keeping it in checin check.