Sentences with phrase «trial study group»

Kramer, M. S., et al., & Promotion of Breastfeeding Intervention Trial Study Group.

Not exact matches

We chose to model the effects on body weight because good evidence (from both trials and epidemiological studies) links regular consumption of sugar sweetened drinks to weight gain.8 10 12 Moreover, data from longitudinal studies support the idea that changes in the price of sugar sweetened drinks are linked to changes in body weight.20 Other groups have used this form of modelling to estimate the effects of a sugar sweetened drink tax on obesity.18 21 22

The result of the study showed that a significant amount more women in the study group went into labor when compared with the control group in each of the three trials.

COMET Study Group UK, «Effect of Low - Dose Mobile versus Traditional Epidural Techniques on Mode of Delivery: A Randomised Controlled Trial,» Lancet 358, no. 9275 (2001): 19 — 23.

One randomized controlled trial comparing home - visited families with control participants who received other community services found a statistically significant difference in mean depressive symptoms at two years post-enrollment, but this contrast was nonsignificant at three years post - enrollment.15 A second study of Early Head Start found no differences in depressive symptoms between intervention and control group participants post-intervention, although a difference was detected at a longer - term follow - up prior to children's enrollment in kindergarten.10 Other randomized controlled trial studies have not found effects of home visitation on maternal depressive symptoms.12, 16,17

A series of randomized control trials of a nurse home visitation program show a range of positive effects on maternal health, including decreases in prenatal cigarette smoking, fewer hypertensive disorders in pregnancy, and fewer closely spaced subsequent pregnancies., A randomized control study of another program that works with a particularly high - risk population found that participant mothers showed significantly lower depressive symptoms than those in the control group and were less likely to report feeling stressed a year after participation.

Controlled clinical trials and observational studies including an internal comparison group

24 randomised and 2 non-randomised trials of intervention packages, including mainly: building community - support or women's groups (9 studies), community mobilisation and antenatal and postnatal home visitation (7 studies), community mobilisation and home - based neonatal treatment (1 study), training traditional birth attendants who made antenatal and intrapartum home visits (2 studies), home - based neonatal care and treatment (2 studies), and education of mothers and antenatal and postnatal visitation (2 studies)

This study is a randomized clinical trial (RCT) with 50 mother / infant pairs in the intervention arm, 50 in one control group and 25 in a third control group.

In addition, there was no effect on breastfeeding duration when the pacifier was introduced at 1 month of age.280 A more recent systematic review found that the highest level of evidence (ie, from clinical trials) does not support an adverse relationship between pacifier use and breastfeeding duration or exclusivity.281 The association between shortened duration of breastfeeding and pacifier use in observational studies likely reflects a number of complex factors such as breastfeeding difficulties or intent to wean.281 A large multicenter, randomized controlled trial of 1021 mothers who were highly motivated to breastfeed were assigned to 2 groups: mothers advised to offer a pacifier after 15 days and mothers advised not to offer a pacifier.

We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (28 January 2013) and reference lists of retrieved studies.

The M@NGO Study (Midwives at New Group practice Options): A randomised controlled trial of caseload midwifery care.

Corruption Trials and Two Reform Reports Make the Case for Action Now In light of the corruption trials of two former legislative leaders taking place this week and New York State's D - minus grade in how it handles issues of integrity from a national comparison study, New York's leading good government groups today called upon the -LSTrials and Two Reform Reports Make the Case for Action Now In light of the corruption trials of two former legislative leaders taking place this week and New York State's D - minus grade in how it handles issues of integrity from a national comparison study, New York's leading good government groups today called upon the -LStrials of two former legislative leaders taking place this week and New York State's D - minus grade in how it handles issues of integrity from a national comparison study, New York's leading good government groups today called upon the -LSB-...]

In light of the corruption trials of two former legislative leaders taking place this week and New York State's D - minus grade in how it handles issues of integrity from a national comparison study, New York's leading good government groups today called upon the New York State legislature and governor to complete the job of reforming our laws governing public ethics.

Mr. Silver's trial is a case study in everything good government groups want to change.

One of the best ways scientists have to prove cause and effect in medicine is to conduct a randomized controlled trial, in which study subjects are randomly assigned to two groups.

One of the limitations of the study was that the component of the trial that studied which students sought help for depression did not have a control group.

Promising results from the new trial would be a major step forward for a field that has long been criticized for studies that are poorly designed, incomplete or lack control - group comparisons, as well as for the peddling of unproved therapies in many clinics worldwide.

Both adverse outcomes need to be studied further, according to Legro, who led a team that hosted the Chinese collaborators at Penn State College of Medicine for five weeks as the group wrote the protocol for the multi-center trial and participated in regular steering committee meetings overseeing the trial.

Another problem is that modeling studies, like this one, are inherently less powerful than other kinds of medical research: randomized clinical trials, the gold standard in medical research, in which patients are randomly assigned different treatments or no treatment; case - control studies, which compare patients who have a condition with those who do not; or cohort studies, which determine the risk of contracting a disease by studying a group of people with similar demographics.

The actual disparity in number of cases between the two groups was small, with 129 lung cancers in all, and the trial wasn't set up to study that disease.

Wyss - Coray, whose group did most of the mouse studies that inspired the clinical trial, now plans to conduct a second, larger trial using plasma from which many proteins and other molecules have been removed.

The study is similar to a clinical trial the Mahidol group recently completed along the Thai / Myanmar border.

We urge the adoption of policies that ensure opportunities for people to participate in research studies and clinical trials without fear that the information generated by their participation will be inappropriately disclosed and adversely affect their health insurance status or that of their families, either as individuals or as members of a particular group.

The new study is a meta - analysis of three randomized controlled trials conducted by the Alliance for Clinical Trials in Oncology (formerly Cancer and Leukemia Group B)(CALGB) with support from the NCI, Intergroupe Francophone du Myélome (IFM), and the Gruppo Italiano Malattie Ematologiche dell «Adulto (GItrials conducted by the Alliance for Clinical Trials in Oncology (formerly Cancer and Leukemia Group B)(CALGB) with support from the NCI, Intergroupe Francophone du Myélome (IFM), and the Gruppo Italiano Malattie Ematologiche dell «Adulto (GITrials in Oncology (formerly Cancer and Leukemia Group B)(CALGB) with support from the NCI, Intergroupe Francophone du Myélome (IFM), and the Gruppo Italiano Malattie Ematologiche dell «Adulto (GIMEMA).

A second study showed that training in realistic environments, including practiced encounters with armed - opponent actors in buildings and streets, improved their shooting accuracy under stress Similarly, trials with 66 of the officers revealed that those who trained weekly on their own in a combat sport such as karate or kickboxing performed better under high - anxiety fights than those with no additional training, although both groups suffered performance decreases when conditions shifted from low to high anxiety.

Although epidemiological studies have suggested that moderate drinking can lower a person's risk of heart attack or stroke, that possibility has not been studied in a randomized trial with a control group.

Principal investigator E. Shelley Hwang, M.D., chief of breast surgery at the Duke Cancer Institute and vice chair of research in the Duke University Department of Surgery, will lead the study through the cooperative group, The Alliance for Clinical Trials in Oncology.

Often clinical studies fall short of the rigorous methodology demanded by «gold standard» clinical trials, in which patients are assigned to treatment groups at random and nobody knows which group is which.

«However, as immunosuppression drugs required for transplantation can have significant adverse side effects, the treatment only makes sense for people who have frequent severe hypoglycemia despite optimal diabetes management, or for those already on immunosuppressant drugs for a kidney transplant, a group being studied in another Phase 3 trial.»

CT - P13 has previously demonstrated pharmacokinetic (PK) equivalence to INX in the PLANETAS trial, a randomised double - blind, parallel group study of 250 patients with AS, and was recently approved by the European Medicines Agency.

The results of the trial — a combined phase 1 and 2 study — strongly support testing of the drug in a larger group of patients in both phase 2 and 3 trials, the authors say.

The study demonstrated that a group of trial participants with low 21 - gene recurrence score (Oncotype DX ® Recurrence Score ®) results of 10 or less who received hormonal therapy alone without chemotherapy had less than a one percent chance of distant recurrence at five years.

«Our population in this trial also had a high response rate in the control group, so further studies are needed in broader populations to assess the efficacy of buprenorphine implants versus sublingual buprenorphine in other settings.»

To address that debate, Kojic's study, dubbed «AIDS Clinical Trials Group Protocol 5240,» measured the safety and immune system response of the vaccine in HIV - positive women aged 13 to 45 with a wide range of immune statuses.

Julia Lewis, MD (Vanderbilt University School of Medicine) and her colleagues in the Collaborative Study Group conducted a 441 - patient randomized clinical trial to test the potential of a compound called ferric citrate to bind phosphorus, increase iron stores, and reduce the usage of IV iron and ESAs.

Although the study began as a randomized trial that divided subjects into four treatment groups (placebo, deprenyl, α - tocopherol, and deprenyl / α - tocopherol), this was terminated early because positive effects of deprenyl were observed and all subjects then received deprenyl for approximately 18 months.

The authors, who are now planning to begin clinical trials based on this study, state that the three enzymes can be promising therapeutic targets for a diverse and broad group of DLBCL patients.

Contrary to the proclamations of many scientists, unreliable medical study results do not disappear with large, randomized controlled trials, in which subjects are randomly assigned to a treatment or placebo group.

Hypertension is the most important treatable risk factor for cardiovascular disease, and while it is especially common in the elderly and in patients with chronic kidney disease (CKD), these are the least studied groups in randomized controlled trials examining the health effects of lowering blood pressure.

The study, published in the July issue of the journal Epidemiology, offers benefits over typically used randomized clinical trials, as such studies are often too small to identify rare side effects or may be performed in a group of patients who do not take other types of medications or have other conditions that could skew the drug's effect in a broader group following approval.

The study — conducted by the Clinical Investigator Collaborative, a multi-centre, Phase II clinical trials group supported by the Allergy, Genes and Environment Network (AllerGen)-- recruited 31 patients over five sites across Canada.

The study was the first randomized - controlled trial to examine the potential benefits of the low fat diet on the management of MS.. The study found no significant differences between the two groups in brain lesions detected on MRI brain scans or on other measures of MS.. But while the number of trial participants was relatively small, study leaders believe the significantly improved fatigue symptoms merited further and larger studies of the diet.

The series started in 2009, when the U.S. government funded a team of researchers to recruit and study participants for the Testosterone Trial — a group of seven long - term studies of how testosterone therapy affects sexual activity, energy level, memory, heart and bone health, and the ability to walk a certain distance.

Their most powerful tool in this job is the randomized controlled trial, a type of experiment in which researchers separate participants into two or more groups and subject some of them to the intervention to be studied, like a new drug or surgical procedure.

For this study, the Swiss researchers pooled data with two other groups that conducted Phase 1 trials of the vaccine in Africa — in Lambaréné, Gabon, and Kilifi, Kenya.

Maria Carrillo, vice president of medical and scientific relations at the Alzheimer's Association, an advocacy group, applauds NIH's giving the trial a green light: Targeting the APOE4 population will «increase the possibility that participants in the trial will become symptomatic during the period of the study so that the scientists can assess whether the drug intervention is having an impact on delaying or preventing Alzheimer's symptoms, without having to wait 10 or 15 years or more,» she says.

For the study, Baron performed an analysis of data from a 2010 clinical trial (by the same group of Northwestern researchers on the current paper) that demonstrated the ability of aerobic exercise to improve sleep, mood and vitality over a 16 - week period in middle - age - to - older adults with insomnia.

Focus group studies revealed that older people across Europe feel that they have the right to be invited to clinical trials, and that they could make the decision to participate themselves.

This is a «drastic» step, says Inder Verma of the Salk Institute for Biological Studies in La Jolla, California, who headed a special working group at the National Institutes of Health that investigated the Gelsinger trial.