Tumour cells need an increased supply of amino acids to support protein and nucleotide synthesis.
Not exact matches
To get into the blood vessels, the
cell needs to penetrate tissue, both when it leaves the
tumour and when it is attaching to a new organ.
«Although relatively rare, childhood germ
cell tumours need to be diagnosed accurately and followed up carefully to give us the best chances of treating them,» says Professor Nick Coleman from the Department of Pathology, University of Cambridge.
The time
needed for breast cancer metastases (secondary lesions caused by
cells that have escaped from the original
tumour) to develop varies between patients, and little is known about the mechanisms that govern latency (the dormant state of
cells that have already spread through the body).
A trained robotic surgeon experienced in the treatment of prostate, bladder and kidney cancer, Assoc Prof Chia said, «For anticancer drugs to achieve their best effectiveness, they
need to penetrate into the
tumour efficiently in order to reach the cystoplasm of all the cancer
cells that are being targeted without affecting the normal
cells.
Many
tumours lack the specific characteristics
needed in order for the immunotherapy to recognise and attack the cancer
cells as enemies.
The commentary highlights the possible fundamentally different and even opposing functions of intestinal fibroblast subpopulations in regulating inflammation and
tumour formation and underscores the
need to further characterize these
cells to reveal new mechanisms underlying pathogenesis of chronic inflammation and cancer.
The enzyme that degrades these chains is called heparanase, and the researchers found that medulloblastoma
cells, as well as
cells from other childhood brain
tumours,
need this enzyme, which may suggest new ways to treat the tumor.