Sentences with phrase «tumours more»

Clinicians in the AHTs Clinical Oncology Unit have encountered a number of young Shar Pei with unusually aggressive mast cell tumours, and previous reports in veterinary medical journals describe an increased incidence of mast cell tumours in Shar Pei, with aggressive mast cell tumours more common in Shar Pei under 2 years of age.

In the last week at least a dozen folks have sent me various articles with sensationalist headlines such as, «Sugar Makes Cancerous Tumours More Aggressive, Finds New Study» and «Scientists Make Breakthrough in Linking Sugar to Cancer Growth»

Hannes Stockinger, the senior author of the study, adds: «If we coupled this delivery method with screening of patient's tumours for the presence of a unique surface protein, which we can target with the Fab fragment - functionalized liposomes, we might be able to treat tumours more efficiently and decrease the side effects of the delivered anti-cancer drugs substantially.

The researchers demonstrated that this process requires FAK in order to work, and without it, these signals are never sent — making the tumour more vulnerable to DNA damaging therapy.

Using ultrasound, Harris hopes to guide radiotherapy treatment to target the tumour more precisely.

Not exact matches

Under Gupta's guidance, Mitacs has worked with 60 universities and more than 6,000 companies to solve real - world challenges — from building better tools to locate lung tumours to modelling the spread of forest fires.

[4] And he suffered a number of serious illnesses ranging from a stomach tumour to the Parkinson's disease which marked his final years - but which did not prevent him from continuing his massive programme of overseas trips, rallies, meetings, conferences, ad limina visits with Bishops, and more.

Salvation Army officer Shaun Skinner shares his story of living with a brain tumour but being used by... More

More displays like tonight at Swansea are badly needed to cure the first cancerous tumour, Wenger, and see him off.

More than # 400,000 is raised for 12 - year - old Ollie Gardiner, who is undergoing pioneering treatment for a brain tumour.

The researchers concluded that patients with circulating tumour cells with more N - terminals than C - terminals had the androgen receptor variants.

We also detected circulating tumour cells, which were found in higher numbers in patients who had received more prior therapies.

They seeded mice with human pancreatic tumours and then injected them daily with the souped - up bacteria for a week, giving them a week off before four more days of injections.

Gravekamp thinks the radioactive bacteria affected metastatic tumours most because cells there were still rapidly multiplying, leaving their chromosomes more open to damage than those in healthy tissues or in the original tumour.

What's more, the bacteria seem to home in on the metastatic tumours.

Tumours in these mice grew 50 per cent more slowly than those in healthy mice, indicating that one extra copy of the gene has a significant effect on tumour growth (Nature, DOI: 10.1038 / nature08062).

«It was really surprizing to realize that oncogenic Pik3ca in basal cells induced the formation of luminal tumours, while its expression in luminal cells gave rise to heterogeneous and more aggressive tumors including basal - like tumors,» comments Alexandra Van Keymeulen, the first author of the paper.

These «aggregates» can comprise hundreds of thousands of cells, be up to 2 mm in diameter and be eight times more resistant to chemotherapy drugs — firstly because hypoxic conditions are created inside the aggregates and secondly because these tumour cells reduce growth and are therefore less sensitive.

RARE but pernicious cancer «stem» cells, blamed for the spread and invincibility of some tumours, may be more vulnerable than we thought.

McKenna and his team have identified four different drugs — including the anti-HIV drug nelfinavir — that can disrupt the process by which hypoxia occurs, restoring proper blood flow to the tumours and making them more vulnerable to chemotherapy (Cancer Research, DOI: 10.1158 / 0008 - 5472.

«Our results indicate it is a promising agent for clinical trials, and a as an add - on to more conventional therapies, to prevent tumour recurrence, further disease progression and metastasis.»

For one thing, you would expect tumours to be more common than they are.

I find myself more concerned with aspects such as checking that the same symbols are used consistently throughout the text, or putting arrows on photos of clinical scans to show the nonspecialist which white blob is actually the tumour.

Devil Facial Tumour Disease (DFTD) is a rare contagious facial tumour, which emerged from a neural (Schwann) cell in a single Tasmanian devil more than 18 yearTumour Disease (DFTD) is a rare contagious facial tumour, which emerged from a neural (Schwann) cell in a single Tasmanian devil more than 18 yeartumour, which emerged from a neural (Schwann) cell in a single Tasmanian devil more than 18 years ago.

By measuring levels of a modified protein, they could identify those who went on to develop secondary tumours within two years, with more than 90 per cent accuracy.

«Pancreatic cancer is extremely hard to treat by chemotherapy, so this finding is important because vitamin A targets the non-cancerous tissue and makes the existing chemotherapy more effective, killing the cancer cells and shrinking tumours.

It would also help refine estimates of how far positronium travels, allowing tumour volumes to be measured more accurately.

In each person, the team found more than 100 mutations in the various tumour samples analysed; only about one - third of them occurred in all samples.

Steven Curley, associate professor of surgery at the University of Texas Anderson Cancer Center in Houston, has tested the gel on 15 people and is optimistic that it will provide a more effective treatment for liver cancer, including secondary tumours that have spread from other parts of the body.

Unlike normal cells, however, the tumour cells are considerably more sensitive, because they can not repair damage well.

Nearly all cancers are still diagnosed by doctors taking a sample of the tumour, a so - called biopsy, then slicing it thinly and staining it with two vegetable dyes used for more than 100 years.

Although these results are an important step forward in understanding the mechanisms of tumour progression, more research is needed before this treatment can be applied to clinical practice.

A more highly publicised case was in 2009, when an Israeli teenager developed brain and spinal tumours after receiving several implants of fetal stem cells in Moscow to treat a rare degenerative condition.

They found that tumours with increased levels of SOX9 more easily metastasise.

The technique, magnetic resonance imaging, is more usually used for examinations such as brain scans to detect tumours.

«Not only that, but the more cadherin - 22 that there is in a tumour, the more advanced the cancer stage and the worse the prognosis is for the patients.»

«On the other hand the US Food and Drug Administration has taken the more conservative approach which recognises that SQUIRE was designed for all - comers without prior selection, and this subgroup analysis is insufficient evidence to conclude that patients with EGFR negative tumours are not candidates.»

Read more about the Tumour Immunotherapy Program at http://www.pm-tumorimmunotherapyprogram.ca/

Our data show that cancer cells without BRCA1 have more than one «Achilles heel,» and so there are more ways to target cancers and therefore to prevent tumours becoming resistant to treatment.»

The new device will allow for more accurate medical procedures that involve the use of ultrasound to kill tumours, loosen blood clots and deliver drugs into targeted cells.

The research team with international collaborators analysed more than 100 patient samples from ovarian and other cancer types to discover a distinct population of cells found in some tumours.

They found that it took longer for the disease to progress in patients whose tumour DNA count in the blood fell by more than a half after one cycle of chemotherapy, compared with patients whose DNA count did not drop.

As well as weakening the tumour, which makes it less able to grow and spread to other parts of the body, the drug made blood vessels become more leaky, enabling more chemotherapy drugs to spill into the tumour.

Prostate cancer patients whose tumour cells have high levels of this molecule are more than twice as likely to see their disease return following surgery.

In addition, the 3D model shared more similarities with a tumour than 2D models including a higher proliferation rate, higher protein expression and higher resistance to anti-cancer drugs.

In addition to helping patients live longer, more patients treated with pembrolizumab responded to treatment and for a longer duration than those treated with chemotherapy; the objective response rate — the percentage of patients whose tumours shrank or disappeared — was almost twice as high with pembrolizumab: 21 % compared to 11 % on chemotherapy.

«Interestingly, this study shows that the very marker that indicates a prostate tumour may be more aggressive, could also be the key to its downfall.»

Growing them in animals makes for more lifelike tumours, and can produce large quantities of tissue for study.

Chemotherapy before surgery might provide a false assurance that there's no more residual cancer, whereas microscopic tumour may remain after the surgery, leading to cancer recurrence and possibly, death.

If the people whose tumours are more likely to spread to the brain could be identified, researchers may be able to prevent this from happening.