If your dog's urine cortisol is within the normal range he most likely does not have
typical Cushing's disease.
It's not uncommon for a veterinarian to inadvertently induce
typical Cushing's by prescribing a too - high dose of oral prednisone — or a course of prednisone therapy that is too long in duration.
While
typical Cushing's involves too much cortisol, «atypical» Cushing's can occur when the outer layer of the adrenals — the zona glomerulosa — overproduces the hormone aldosterone.
The resulting signs are similar to signs of
Typical Cushing's.
The first form is
Typical Cushing's disease.
The most common cause of
Typical Cushing's is the pituitary gland overproducing ACTH.
In
Typical Cushing's, the adrenal cortex produces too much cortisol.
Not exact matches
Though many dogs have no clinical signs of illness other than blindness, some dogs will show signs
typical for
Cushing's disease (increased thirst, increased urination, weight gain) though they usually test negative for
Cushing's disease.
Owners usually report observing symptoms
typical of
Cushing's for 6 months to as long as 6 years before seeking veterinary attention.
Dogs with this atypical disorder generally respond to drugs like mitotane or trilostane, similar to dogs with
typical or classical
Cushing's disease.