Sentences with phrase «understanding mechanisms of change»
She is the author of Neurobiologically Informed Trauma Therapy with Children and Adolescents: Understanding Mechanisms of Change» published by WW Norton.
https://parentsplace.jfcs.org/ Not exact matches
As a cancer researcher, do you think the mechanisms of tumor growth are somehow changing to come into line with your perceptions, or is it possible that the process of our learning more about DNA mutations and cell architecture and nutrient exchange and epigenetic effects make it possible for us to inch ever closer to understanding that which is already going on under our noses?
He said: «The Darwinian mechanism that's used to explain all evolutionary change will be relegated, I believe, to being just one of several mechanisms — maybe not even the most important when it comes to understanding macroevolution, the evolution of major transitions in body type.»
«For example, there's no political polarization on climate change with greater understanding of the greenhouse mechanism that drives global warming,» he wrote in an email.
«Unless you «photograph» the changes that a protein undergoes and understand its movement and therefore the underlying molecular mechanism, this process is a mystery,» explains Laura Orellana, first author of the article.
Understanding the mechanisms that drive migratory behavior is increasingly important, Beck said, in terms of climate change, as migrating animals rely on multiple habitats.
The authors note that understanding the mechanisms that mediate migratory sleeplessness may provide insights into the etiology of changes in sleep and behavior in seasonal mood disorders, as well as into the functions of sleep itself.
«When you match physiologic changes in the brain with behavioral impairment, you can start to understand the biological mechanisms of this disorder, which may help improve diagnosis, and, in time, treatment.»
Furthermore, unraveling the causes of sea ice retreat should help us understand the mechanisms behind climate change on a global level, which is interrelated to the ice reduction in the Arctic ocean.»
The way epigenetics helps understand that process is that it provides the mechanism by which maternal experience of a pup can essentially produce lifelong changes in the brain because many epigenetic changes are that stable.
The scientists conclude that the study reveals an essential function for CTCF in the orchestration of transcriptional changes during the terminal differentiation of B lymphocytes and advances understanding of the mechanisms that regulate the immune response.
«Recent advances in understanding coral resilience are essential to safeguard coral reefs: A review of the literature points to the importance of reducing global carbon dioxide emissions in addition to protecting or augmenting resilience mechanisms in the face of increased frequency of climate change impacts..»
«These two types of abrupt change events appear to have different degrees of tropical Pacific involvement, and because the tropical Pacific speaks with such a loud voice when it does speak, we think this is extremely important for understanding the mechanisms underlying these events.»
To better understand these mechanisms, Too and colleagues infected human motor neuron cells with EV71 and compiled a list of human proteins that showed changes in activity during infection.
To gain an understanding of the mechanism that connects low mtDNA levels with a cellular change that leads to cancer and metastasis, Guha, Avadhani and their colleagues set up two systems by which they could purposefully reduce the amount of mtDNA in a cell.
Australia has created an adaptation program to «help Australians better understand climate change, manage risks, and take advantage of potential opportunities;» In Nigeria, state and local governments are developing action plans for high - risk urban areas, while the federal government is seeking to expand forests by reducing deforestation and wood fuel demand; in Mali, significant efforts are being made to conserve water resources, as well as create usable mechanisms to track the development of climate change.
«There is an emerging understanding of the physical mechanisms behind changes in the monsoons and tropical rainfall after such eruptions,» says Toohey.
Scientists are still only just beginning to understand the myriad mechanisms that control the seemingly dramatic melting observed in regions of West Antarctica, and how climate change is affecting all the moving parts.
This is not a very conceptually satisfying situation and does little to advance our understanding of the mechanism (s) underlying the changes in gene expression in response to the perturbation or its implications for clinical phenotype.
«Getting a better understanding of the exact mechanisms that are underlying these changes, will be critical,» said Morrison.
The goals of the research areas are to understand the neurobiological mechanisms underlying drug abuse and addiction, with special emphasis on changes that occur during chronic drug use, withdrawal and relapse.
We use a number of experimental approaches to gain a greater understanding of translational control mechanisms necessary for maintaining long - lasting changes in synaptic strength and memory.
Thus, research aimed at fully understanding the mechanisms by which plants either defend against, or succumb to infection / infestation is of paramount importance to facing the global challenges of feeding a burgeoning population amidst a changing climate.
The goal of the PCCO is to provide tools for improving public understanding of the mechanisms driving climate change, and possible responses to prevent or adapt to change.
Despite their fundamental importance in the regulation of cell physiology, the mechanisms that confer cell adaptability to changes in the microenvironment are poorly understood.
«This work is a major step forward in understanding the molecular mechanisms that direct the changes in the chemical forms of plutonium,» said Dr. Andrew Felmy, a geochemist and lead author of the study.
To understand the mechanism of biological processes, time - resolved methodologies are required to investigate how functionality is linked to changes in molecular structure.
The International Polar Foundation and SANAP will join forces on the development of the Polaris Climate Change Observatories (PCCO) in Cape Town, state of the art venues informing public understanding of the mechanisms driving climate change and exploring ways of adapting to the transformations the Earth is experieChange Observatories (PCCO) in Cape Town, state of the art venues informing public understanding of the mechanisms driving climate change and exploring ways of adapting to the transformations the Earth is experiechange and exploring ways of adapting to the transformations the Earth is experiencing.
However, the mechanisms by which changes in the composition of the intestinal microbiota regulate allergic responses to food remain poorly understood.
The biological mechanisms of lifespan extension through calorie restriction are not fully understood, but researchers say it may involve alterations in energy metabolism (as mentioned above), reduced oxidative damage, improvements in insulin sensitivity, reduction of glycation, modulation of protein metabolism, downregulation of pro-inflammatory genes and functional changes in both neuroendocrine and autonomic nervous systems.
This strategy requires the continuous refinement of new theories of change that are grounded in a growing scientific understanding of the causal mechanisms that explain how early experiences are built into the body and influence lifelong outcomes in learning, behavior, and both physical and mental health.
The approach presented here is based on three main pillars: an adaptation mechanism based on a broad understanding of system dependencies; efficient use of system knowledge through involvement of actors throughout the process; and technological solutions to enable efficient actor communication and information handling.The book provides readers with a better understanding of the factors that influence decisions, and put forward solutions to facilitate the rapid adaptation to changes in the business environment and customer needs through intelligent upgrade i...
Stacy Byers, PhD, Washington State University «Reducing the Risk of Transmission of Pathogenic Bacteria to Bighorn Sheep» Mary Klinck, DVM, University of Montreal «Creating Validated Pain Scales for Feline Osteoarthritis Pain Identification and Quantification» Alex Davies, PhD University of California — Davis «Understanding Mechanisms that Contribute to Early Changes in Cancer Stem Cells» Kristen Messenger, DVM, North Carolina State University «Analgesic Drug Therapy in Animals» Tiffany Wolf, DVM, University of Minnesota «Identification of Factors Contributing to Mycobacterium Tuberculosis Transfer between Humans and Great Apes»
What we need are real - time mechanisms for rationally interacting with these complex systems, understanding that fundamental (unpredictable) change is the order of the day, not an exception that can be brushed away.
But to understand the mechanisms of climatic changes, one needs to know the sequence of events — for example, one needs to know whether a particular warming in Antarctica happens before, after, or at the same time as a warming in Greenland.
The uncertainties in the historical tropical cyclone records, the incomplete understanding of the physical mechanisms linking tropical cyclone metrics to climate change, and the degree of tropical cyclone variability provide only low confidence for the attribution of any detectable changes in tropical cyclone activity to anthropogenic influences.
It is (virtually) impossible to prove that a single (or a small number) freak weather event (s) is (are) caused by increasing CO2, but when a large number are observed, it may be possible to spot a pattern of change — yet it is difficult to attribute such a change to a cause unless the mechanisms are understood.
While we don't know precisely why the CO2 changes occur on long timescales, (the mechanisms are well understood; the details are not), we do know that explaining the magnitude of global temperature change requires including CO2.
It is interesting that biology has, in the case, provided a universal theory based on a single simple mechanism (if we include genetic drift and neutral theory, though admittedly not part of Darwin's formally stated understanding), whereas physics has not done so for climate change, given that it is potentially caused by many different mechanisms.
Determining the mechanisms and feedbacks involved in climate change at the end of the last ice age therefore requires an understanding of the relationship between the southern margin ice retreat and connected meltwater events to atmospheric and sea surface temperatures, ice - rafting Heinrich events, sea level rise, and atmospheric greenhouse gas concentrations.
Great progress has been made in understanding the causes and mechanisms of these climate changes.
What I don't understand is what physical mechanism is responsible for altering the flow (say, at 300 hPa) and changing the meridional structure of the mid-latitude circulation.
The overarching goal of this WCRP research effort, led by WCRP's Core Project «Climate and Ocean Variability, Predictability and Change» (CLIVAR) as a Research Focus, is to establish a quantitative understanding of the natural and anthropogenic mechanisms of regional to local sea level variability; to promote advances in observing systems required for an integrated sea level monitoring; and to foster the development of sea level predictions and projections that are of increasing benefit for coastal zone management.
We do know that ocean basins produce this oscillatory behavior — the El Nino / Southern Oscillation, the Arctic Oscillation, the Pacific Decadal Oscialltion, the NAO, the Madden - Julian Oscillation (Indian Ocean), but they seem to have a bit of a random component, their forcing mechanisms are poorly understood, their «phase changes» appear impossible to predict very far in advance, and they must also be sensitive to the overall climate warming.
The US CLIVAR ENSO Diversity Working Group was formed to clarify, coordinate and synthesize research to achieve a better understanding of ENSO diversity, including surface and sub-surface characteristics, tropical - extratropical teleconnections, physical mechanisms predictability, and relationship with climate change.
Given our understanding of the climate system and the mechanisms involved in abrupt climate change, this committee concludes that human activities could trigger abrupt climate change.
The US CLIVAR ENSO Diversity Working Group was formed in 2012 to clarify, coordinate and synthesize research to achieve a better understanding of ENSO diversity, including surface and sub-surface characteristics, tropical - extratropical teleconnections, physical mechanisms predictability, and relationship with climate change.
Reviewing the document today, one can't help but be struck by how well these scientists understood the mechanisms of Earth's climate change 50 years ago.
Our understanding 48 of the «ion - aerosol clear air» mechanism as a whole relies on a few model investigations that simulate GCR 49 changes over a solar cycle (Kazil et al., 2012; Pierce and Adams, 2009a; Snow - Kropla et al., 2011) or during 50 strong Forbush decreases (Bondo et al., 2010; Snow - Kropla et al., 2011).
For instance, researchers still don't completely understand the role of aerosols in the atmosphere, the variable effects of clouds at different heights, and the influence of feedback mechanisms such as the changing reflectivity of the Earth's surface and the release of gases from permafrost or deep seabeds.