Sentences with phrase «using functional studies»

Project Title: Using functional studies to explore potential high penetrance melanoma susceptibility genes identified using whole exome and genome sequencing.

A successful candidate should have the following qualifications: a Ph.D. in the field of Molecular Biology, Cell Biology, Biochemistry or related field; an established track - record of publications in peer - reviewed journals; solid experience in the biochemistry of complex DNA - binding proteins (such as chromatin remodeling factors or DNA repair proteins), their purification from heterologous expression systems as well as their characterization using functional studies such as by isothermal titration calorimetry fluorescence, transcription assays.

Not exact matches

A study published in Current Biology used functional magnetic resonance imaging (fmri) of the brains of three to seven month old infants to assess brain activity in relationship to sound.

In the new study, the researchers used functional magnetic resonance imaging (fMRI) to record brain responses in sleeping babies while they were presented with emotionally neutral, positive, or negative human vocalizations or nonvocal environmental sounds.

The study team conducted a series of behavioral and brain imaging studies using functional magnetic resonance imaging (fMRI).

Researchers used functional MRI to study the recovery of 12 high school football players with concussion and compared them to 12 uninjured teammates.

To date, there have been no studies looking at functional recovery following exhaustive running and the use of compression garments.

This study used a randomized controlled double - blinded design to determine the functional recovery effects of wearing below - knee compression socks compared with placebo noncompressive below - knee socks.

A new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging using magnetic resonance imaging (MRI) reports a link between reduced functional activation and reduced cortical thickness in the brains of patients with bipolar disorder.

In a new study, published today in the journal Advanced Functional Materials, researchers used a combination of 3D imaging and 3D printing techniques to create a custom silicone guide implanted with biochemical cues to help nerve regeneration.

Focusing on the neural pathway from the brain's prefrontal cortex to the amygdala, they combined optogenetics — a technique that uses light to control the activity of neurons in living tissue — with behavioral testing, a methodology that allows researchers to study functional connections between different regions of the brain.

The computational method is also so general that it can be used to study all sorts of other proteins bound to various types of functional molecules,» says Johan Åqvist.

Using data from National Database for Autism Research (NDAR), lead author Kristina Denisova, PhD, Assistant Professor of Psychiatry at CUMC and Fellow at the Sackler Institute, studied 71 high and low risk infants who underwent two functional Magnetic Resonance imaging brain scans either at 1 - 2 months or at 9 - 10 months: one during a resting period of sleep and a second while native language was presented to the infants.

In the future, studies are aimed at using novel molecular approaches to selectively delete AMPK in specific brain regions associated with nicotine dependence to better understand the functional role of this protein in addiction.

In a study under way at USP's Neuroimaging Laboratory (LIM - 21), the researchers are now seeking to correlate the cognitive profile observed in the two groups of cocaine - dependent patients with decision - making and resting - state brain activity, using functional magnetic resonance imaging (fMRI).

In this new study and for the first time, scientists used functional magnetic resonance imaging (fMRI) combined with a standard clinical trial design to derive an unbiased brain - based neurological marker to predict analgesia associated with placebo treatment in patients with chronic knee osteoarthritis pain.

For the present study, researchers used functional magnetic resonance imaging (fMRI) to assess brain response to sensory stimulation in 35 women with fibromyalgia and 25 healthy, age - matched controls.

The team's approach relied on methods developed in the past decade or so to study «functional connectivity» in the adult human brain — essentially using fMRI to determine which brain regions have synchronized activity when the subject is not engaged in any particular task.

The result was the largest deletion ever observed in the dystrophin gene using CRISPR / Cas9, and the study was the first to create corrected human iPS cells that could directly restore functional muscle tissue affected by Duchenne.

Dr. Aron and colleagues based their study's conclusions on a neuroimaging study using functional magnetic resonance imaging (fMRI) scanning that measures brain activity by detecting changes in blood flow.

Led by neurologist Bradley Schlaggar, the group studied 238 healthy volunteers, 7 to 30 years old, using functional MRI, a technique that identifies active neural circuits based on blood flow and blood oxygen levels.

«Our results demonstrate for the first time that human adult skin cells can be used to efficiently and rapidly generate functional pancreatic cells that behave similar to human beta cells,» says Matthias Hebrok, PhD, director of the Diabetes Center at UCSF and a co-senior author on the study.

Earlier, for his Ph.D., he used his physics training to study biological interactions at the molecular resolution — but for his postdoc he changed approaches dramatically, turning to cell biology and applying his skills to the development of high - resolution functional imaging of DNA transcription in living cells.

Johnson, along with study co-author and post-doctoral researcher Jingyun Ye at the University of Pittsburgh, examined a series of eight different functional groups of Lewis acid and base pairs (Lewis pairs for short), which are highly reactive compounds often used as catalysts.

Over three days, Muzik and Diwadkar studied Hof's brain and body functions using two distinct imaging techniques — including functional magnetic resonance imaging (fMRI) to study his brain and positron emission tomography (PET) to study his body.

Neuromania: On the Limits of Brain Science (Oxford University Press, 2011) debunks the budding idea that a study or news report accompanied by a colorful brain image is more reliable than research that does not use flashy functional MRI technology.

These comprised not only «conventional» behavioral studies, but also the physical effects on the brains of test participants by measuring the Blood Oxygen Level - dependent (BOLD) response using functional Magnetic Resonance Imaging (fMRI) scans.

The fNIRS scans indicated that the concussed brain activated at a lower threshold and drew from a wider area — a sharp contrast from earlier functional magnetic resonance imaging (fMRI) studies using concussion patients.

«Our study sets the stage for further research to identify which additional cues could induce these neurons to fully mature and incorporate into functional circuits, thereby allowing this approach to potentially be used in the clinic,» Berninger says.

This is important to the study of mental illness, says Cole, who made the discovery using functional magnetic resonance imaging (fMRI), because it is easier to analyze a brain at rest.

CU Boulder researchers used functional MRI scans (fMRI) to study brain activity in a group of 37 fibromyalgia patients and 35 control patients as they were exposed to a variety of non-painful visual, auditory and tactile cues as well as painful pressure.

Sinha and her colleagues used functional magnetic resonance imaging to study brain activity in people exposed to stimuli ranging from highly stressful — images of mutilated bodies or someone pointing a gun — to neutral, such as a chair, table or lamp.

Different types of cognitive tasks spur activity in various regions of the brain, as indicated by studies using functional magnetic resonance imaging (fMRI).

In a 2005 Harvard University functional imaging study of working memory — that short - term memory we use to carry on conversations or remember telephone numbers — a group of volunteers were given verbal attention tasks while inside the scanning machine.

Measures of pain, functional impairment, and use of health care resources were not different between the study groups at 7 days or at 3 months after the emergency department visit.

She stayed on as a postdoc in the same microbiology group and now studies the functional genomics and bioenergetics of Saccharomyces cerevisiae to improve its use in winemaking.

In recent years, songbirds» similarities to human vocal learning have piqued researchers» interests in using them as a functional animal model to study the neurological basis for Huntington's disease.

Building on this research in their latest study, the team analysed liver samples from 2000 patients with Hepatitis C, using state - of - the art genetic and functional analysis, to determine the specific IFNL protein responsible for liver fibrosis.

Using functional magnetic resonance imaging (fMRI), an imaging technique that measures brain activity, researchers examined all three groups at the beginning (baseline), middle, and end of the study while participants performed computer - based speed tasks in the scanner.

Brain scans In the study, researchers scanned the brains of 39 depressed patients and 37 healthy people using functional magnetic resonance imaging (fRMI).

The study was conducted by using positron emission tomography (PET) and functional magnetic resonance imaging (fMRI).

However, in the current study, when the investigators used mutant bacteria that could not make functional pili and flagella, the bacteria could still infect the mice.

According to a groundbreaking study published in this week's online edition of the Proceedings of the National Academy of Sciences, they have chemically synthesized a record - length mirror - image protein and used this protein to demonstrate that a cellular chaperone, which helps «fold» large or complex proteins into their functional state, has a previously unappreciated talent — the ability to fold mirror - image proteins.

The study, published online July 29 in Cerebral Cortex, used functional magnetic resonance imaging, or fMRI, to examine children's brain activity at rest and during two tasks: solving simple math problems and looking at pictures of different faces.

A number of studies have used functional MRI to see what our brain looks like as we recall pleasant memories, watch scary movies or listen to sad music.

Previous studies have used functional magnetic resonance imaging (fMRI) scans to show that similar areas of the brain are activated when someone is in pain and when they see another person in pain.

In the first study to examine the intrinsic functional connectivity of the brain in relation to social media use, Dar Meshi and colleagues observed connectivity between regions of the brain previously established to play a role in self - cognition, in 35 participants.

Researchers using functional MRI (fMRI) have found that neurofeedback training has the potential to reduce the severity of tinnitus or even eliminate it, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

Next, Yolanda Schaerli, first author of the study, successfully demonstrated that the four networks are functional by building them in the bacteria E. coli using the tools of synthetic biology.

The focus of the study was to investigate the association of body mass index to survival, health care use and functional deficiencies following a severe sepsis hospitalization.