Not exact matches
According to the latest neuroscience, the
human brain
uses neurons in the left visual cortex to process written words as whole word units.
In another example, he
uses the example of
human vision: the cortex predicts what should be seen and the mind fills in the gaps; in other words interpretation takes place according to expectation, so context even changes the way that
neurons function.
Professor Wilmut stressed that he and his team had no intention of trying to produce cloned
humans, but intended only to
use the embryos for research into the distressing degenerative condition Motor
Neuron Disease.
This discovery will help researchers understand how
neurons are
using environmental temperature in addition to light to regulate sleep timing in mammals, including
humans.
«It looks like clock
neurons are able to get the temperature information from external thermoreceptors, and that information is being
used to time sleep in the fly in a way that's fundamentally the same as it is in
humans,» Shafer said.
But showing that circadian clock
neurons in fruit flies
use external temperature to trigger sleep suggests that some clock
neurons in
humans could be similarly sensitive.
USING YOUR BRAIN In «The Limits of Intelligence,» Douglas Fox points out that
human intelligence is limited by communication among
neurons in the brain, which is limited in turn by the size of our
neurons.
«A network of artificial
neurons learns to
use human language: A computer simulation of a cognitive model entirely made up of artificial
neurons learns to communicate through dialogue starting from a state of tabula rasa.»
Researchers at Geron, meanwhile, had successfully derived
neurons from
human embryonic stem cells and were pursuing research that would eventually look to repair the damage caused by spinal - cord injuries, a possible
use for embryonic stem cells that was much touted at the time.
Sensory
neurons in
human muscles provide important information
used for the perception and control of movement.
The ANNABELL model is a cognitive architecture entirely made up of interconnected artificial
neurons, able to learn to communicate
using human language starting from a state of «tabula rasa» only through communication with a
human interlocutor.
A group of researchers from the University of Sassari (Italy) and the University of Plymouth (UK) has developed a cognitive model, made up of two million interconnected artificial
neurons, able to learn to communicate
using human language starting from a state of «tabula rasa,» only through communication with a
human interlocutor.
Within a decade, we should be able to
use these technologies to read and alter the state of
neurons for an enormous fraction of the cells in
human brains.
The results obtained by Afsaneh Gaillard's team and that Pierre Vanderhaeghen at the Institute of Interdisciplinary Research in
Human and Molecular Biology show, for the first time,
using mice, that pluripotent stem cells differentiated into cortical
neurons make it possible to reestablish damaged adult cortical circuits, both neuroanatomically and functionally.
Using computer processors that behave like
neurons in the neocortex, Henry Markram is inching closer to building a simulated
human brain — a truly conscious machine.
It
uses computers to simulate the actual workings of an entire brain — a mouse's first, then a
human's — all the way down to the biochemical level of the
neuron.
To replicate these cell culture results, Rani
used human stem cells to grow
neurons into what is called a mini brain.
The virtual world
used in the study was very similar to virtual reality environments
used by
humans, and
neurons in a rat's brain would be very hard to distinguish from
neurons in the
human brain, Mehta said.
Thus, by monitoring the activity of motion - detecting
neurons in animals and simultaneously exploring
human motion perception
using cunningly contrived displays such as a, b and c, scientists are starting to understand the mechanisms in your brain that are specialized for seeing motion.
Cell culture systems
used today also do not faithfully represent the features of
human neurons.»
But no other group has
used implanted electrodes to monitor so many
human neurons at once or had such impressive results.
The data would be
used to better predict
human response to countermeasures, viruses or pharmaceutical drugs, and could help scientists determine if certain types of
neurons are more susceptible to exposure.
The study, published Feb. 16 in PLOS Biology, made
use of a mutant zebrafish strain that models
human Hirschsprung disease, which is caused by loss of the gut
neurons that coordinate gut contractions.
For the new study, the team
used a cell - reprogramming technique (similar to those
used to reprogram skin cells into stem cells) to generate
human DRG - type sensory
neurons from ordinary skin cells called fibroblasts.
But it wasn't until May this year that researchers measured the firing of mirror
neurons in
humans directly,
using electrodes implanted in the brains of epileptic patients awaiting surgery (Current Biology, vol 20, p 750).
Mirror
neurons were first discovered in macaques in the 1990s, and brain scans
using functional MRI had hinted that they exist in
humans too.
About a decadelater he invented an electronic mainframe computer called the Connection Machine that worked somewhat like a
human brain; instead of one processor, it had 65,536, all firing at once like buzzing
neurons, a model that supercomputers have
used ever since.
In tests
using human neural progenitor cells (NPCs)-- self - renewing, multipotent cells that generate
neurons and other brain cell types — the scientists found that exposure to sofosbuvir not only rescued dying NPCs infected with the Zika virus, but restored gene expression linked to their antiviral response.
«We
used human skin cells that we obtained from patients affected with ALS and converted them into
neurons via a technology called induced pluripotent stem cell production,» she explains.
Using mouse and
human - derived dopamine
neurons, researchers found that dopamine movement is affected by changes in electrical properties of the
neurons.
More than 50 years later, scientists have found a way to
use radioactive carbon isotopes released into the atmosphere by nuclear testing to settle a long - standing debate in neuroscience: Does the adult
human brain produce new
neurons?
Motor nerve - like tissue (right) was generated
using human induced pluripotent stem cell - derived motor
neurons (left).
«The number of software - based
humans vastly exceeds those still
using native
neuron - cell - based computation,» he wrote.
Dr. Sonntag studies this concept on the molecular and cellular level
using a translational research approach that integrates the analysis of
human material, such as postmortem brains, primary cell systems, and neural cell populations generated from patients» - or healthy individuals» - derived induced pluripotent stem cells (iPSC), or induced
neurons (iNs), in combination with molecular, biochemistry, and lentivirus - mediated gene - engineering technologies.
In this context, Dr. Woo's work focuses on deepening the understanding of these mechanisms based on postmortem
human brains and animal studies
using a variety of protein and gene expression techniques, in addition to the utilization of differentiated
human neurons.
In the study, published in the Proceedings of the National Academy of Sciences, the scientists
used both rat
neurons and
human neurons created from induced pluripotent stem cells.
The George lab has made seminal contributions to the field including: discovering a novel population of
neurons in the brain of
humans, rats and mice that are involved in nicotine dependence, identifying neuronal ensembles responsible for nicotine and alcohol addiction, and unveiled the cellular and molecular changes associates with long term
use of nicotine, cocaine, methamphetamine and alcohol
use on the brain.
Sitting by himself in the lab, late at night, he stared at the screen of the oscilloscope he
used to track the
neurons» electrical fluctuations, becoming the first
human to witness memories being physically written on the brain.
Using 14C dating we could show that the generation of new cardiomyocytes and
neurons in
humans is not restricted to development but instead continues throughout life (Bergmann et al., 2015; Spalding et al., 2013).
Recently, his lab
used induced pluripotent stem (iPS) cells — adult cells made to act like embryonic stem cells — made from skin cells of patients carrying apoE4, or other mutations related to Alzheimer's, to study their effects on the development, survival, and degeneration of
human neurons.
Although Wang says there is still a long way before such an experiment is tested in
human clinical trials, he believes that in theory, if scientists could develop drugs or
use electrical stimulation that activates D2
neurons, then alcoholics might be prevented from wanting another bottle of beer.
Using iPSC - derived
human DA
neurons from opioid - dependent subjects to study dopamine dynamics Sheng Y, Filichia E, Shick E, Preston KL, Phillips KA, Cooperman L, Lin Z, Tesar P, Hoffer B, Luo Y. Brain and Behavior.
Her lab is
using stem cells to study the function of the disease - causing gene and to generate
human neurons suitable for transplantation and pharmacological screening.
Stem cell researchers from UCLA
used a high resolution technique to examine the genome, or total DNA content, of a pair of
human embryonic stem cell lines and found that while both lines could form
neurons, the lines had differences in the numbers of certain genes that could control such things as individual traits and disease susceptibility.
The study
used three cell types:
human motor
neurons derived from induced pluripotent stem cells, rat cortical cultures, and
human breast cancer cells.
Using a discovery platform whose components range from yeast cells to
human stem cells, Whitehead Institute scientists have identified a novel Parkinson's disease drug target and a compound capable of repairing
neurons derived from Parkinson's patients.
Dr. Pfaff has developed a novel embryonic - stem cell - based model of SMA that phenocopies the pathology of
human SMA, and can be
used to study the basis of the disease and screen for compounds that might increase survival of motor
neurons.
The team
used genetically engineered mice to study the effects of different
human apoE variants on the maturation of neural stem cells or progenitor cells, from which new
neurons develop in the adult brain.
CAMBRIDGE, Mass. —
Using a discovery platform whose components range from yeast cells to
human stem cells, Whitehead Institute scientists have identified a novel Parkinson's disease drug target and a compound capable of repairing
neurons derived from Parkinson's patients.
Does this mean we're close to a
human therapy
using injections of healthy
neurons to repair damaged spines?