Changes in Bordetella are one likely factor in pertussis's rebound, agrees Henry Shinefield, co-director of the Kaiser Permanente
Vaccine Study Center in Oakland, California.
Researchers at the Kaiser Permanente
Vaccine Study Center in Oakland, Calif., studied the medical records of mothers who gave birth to babies between 2010 and 2015.
«This study demonstrates that despite high rates of Tdap vaccination, the growing number of adolescents who have received only the newer acellular pertussis vaccines continue to be at higher risk of contracting whooping cough and sustaining epidemics,» said lead author Nicola Klein, MD, PhD, co-director of the Kaiser Permanente
Vaccine Study Center.
The new formula's reduced effectiveness is most likely driving the recent epidemics of pertussis, says the study's lead author, Nicola Klein, co-director of Kaiser Permanente
Vaccine Study Center in Oakland, Calif..
Not exact matches
«Even with the new immunological
studies, we can't tell what's special about the whole - cell
vaccine that makes it better,» says Kathryn Edwards, the director of the Vanderbilt University School of Medicine Vaccine Research
vaccine that makes it better,» says Kathryn Edwards, the director of the Vanderbilt University School of Medicine
Vaccine Research
Vaccine Research
Center.
«Based on epidemiological
studies, the 9vHPV
vaccine could prevent approximately 90 percent of cervical cancer, 90 percent of HPV - related vulvar and vaginal cancer, 70 to 85 percent of high - grade cervical disease in females, and approximately 90 percent of HPV - related anal cancer and genital warts in males and females worldwide,» explained Anna R. Giuliano, Ph.D., Director of the
Center for Infection Research in Cancer at Moffitt.
The researchers, including those from Moffitt Cancer
Center, published the final results of a
study showing the newest
vaccine is highly effective at preventing HPV infection and disease.
«What this
study tells us is that if more and more people choose not to get a
vaccine,» says Paul Offit, director of the Vaccine Education Center at The Children's Hospital of Philadelphia, «then you'll have bigger and bigger outbreaks.
vaccine,» says Paul Offit, director of the
Vaccine Education Center at The Children's Hospital of Philadelphia, «then you'll have bigger and bigger outbreaks.
Vaccine Education
Center at The Children's Hospital of Philadelphia, «then you'll have bigger and bigger outbreaks.»
The multi-center
study enrolled 31,989 participants from 126 research
centers in the U.S. and Canada during the 2011 - 2012 and 2012 - 2013 influenza seasons in the Northern Hemisphere in order to compare the high - dose trivalent
vaccine versus the standard - dose trivalent
vaccine in adults over 65 years of age.
A few months later, he was working at the International
Center for Genetic Engineering and Biotechnology (ICEGB) in Delhi,
studying malaria
vaccines.
By
studying healthy people, researchers from the National Institute of Allergy and Infectious Diseases (NIAID)
Vaccine Research
Center, part of the NIH, and colleagues from King's College London have created a reference resource for other scientists.
One goal of the
study is to demonstrate the prevalence of H. influenzae in the region, explains Joel Ward, director of the
Center for
Vaccine Research at the University of California, Los Angeles, and scientific adviser to IVI.
«HPV
vaccines could dramatically reduce the incidence of HPV - associated cancers, but uptake of these
vaccines is far lower than for other routine childhood and teen immunizations,» said Kevin A. Henry, PhD, an assistant professor in the Department of Geography and Urban
Studies at Temple University in Philadelphia and member of Fox Chase Cancer
Center's Cancer Prevention and Control program.
«An RSV
vaccine with this M2 - 2 deletion could tip the balance toward a better immune response, which is what we predicted based on earlier laboratory
studies,» says
study leader Ruth A. Karron, MD, director of the
Center for Immunization Research and a professor in the Department of International Health at the Bloomberg School.
In a March 2009
study published in Genes and Immunity, researchers at the National
Center for Computational Toxicology compared the genetic signatures of 16 people who experienced smallpox
vaccine side effects, including fever, rashes and enlarged lymph nodes, to 45 people who did not.
«Although data clearly indicate better immune responses and
vaccine efficacy against both genital warts and cervical dysplasia when vaccination occurs before age 14, this
study suggests that HPV vaccination may be effective in reducing abnormal Pap test results even after sexual debut,» explained co-author Rebecca Perkins, MD, MSc, assistant professor of Obstetrics and Gynecology at Boston University School of Medicine and a gynecologist at Boston Medical
Center.
Researchers led by a team at Duke University identified these immunologic variations by
studying blood samples collected from people living with HIV by the NIAID - supported
Center for HIV / AIDS
Vaccine Immunology (CHAVI).
In the preclinical
study, WRAIR and the Beth Israel Deaconess Medical
Center tested two Zika virus
vaccine candidates: a DNA
vaccine developed at Harvard based on a Zika virus strain isolated in Brazil, and a purified inactivated virus
vaccine developed at WRAIR based on a Zika virus strain isolated in Puerto Rico.
The Walter Reed Army Institute of Research (WRAIR) and collaborators at the Beth Israel Deaconess Medical
Center and Harvard Medical School have completed a promising preclinical
study of two Zika
vaccine candidates that suggests that an effective human
vaccine will be achievable.
«This is an important demonstration of the possibilities opened up for immunotherapy by DMAb technology to direct in vivo production of antibodies of major relevance to human cancer,» said David B. Weiner, Ph.D., executive vice president of The Wistar Institute, director of The Wistar Institute
Vaccine & Immunotherapy
Center, W.W. Smith Charitable Trust Professor in Cancer Research, and senior author of the
study.
«You certainly can't do a $ 100 million
study for every candidate
vaccine that appears safe and immunogenic,» says Mark Mulligan, a molecular virologist who heads the
vaccine center at Emory University in Atlanta and does human challenges with norovirus and tuberculosis.
Researchers at the Mailman School of Public Health and Columbia University Medical
Center studied the impact of text message reminders for the second dose of influenza
vaccine required for many young children to protect them against the virus.
A new
study led by scientists at Beth Israel Deaconess Medical
Center (BIDMC) shows that an HIV - 1
vaccine regimen, involving a viral vector boosted with a purified envelope protein, provided complete protection in half of the vaccinated non-human primates (NHPs) against a series of six repeated challenges with simian immunodeficiency virus (SIV), a virus similar to HIV that infects NHPs.
The
studies support the concept of using natural exposure in combination with malaria - fighting drugs to help people build up protection against disease, says malaria
vaccine researcher Robert Sauerwein of the Radboud University Nijmegen Medical
Center in the Netherlands.
«Currently, there is a lot of focus on the use of antibodies transferred passively or through a
vaccine to prevent infection in infants, however this
study cautions against that and suggests that broadly neutralizing antibodies may actually aid in enhancing transmission from mother to child,» added Sagar, an attending physician in infectious diseases at Boston Medical
Center.
This new work suggests that anti-PD-1 antibodies might be equally effective in treating hepatitis C and other persistent human viral infections, says Christopher Walker, PhD, a senior author on the
study and director of the
Center for
Vaccines and Immunity at Nationwide Children's.
The
Center has a GMP pilot plant being able to produce recombinant antigens for
vaccine formulations, formulation
studies with the SSI CAF cased adjuvants is performed in laboratories using qualified equipment and procedures.
Dr. Polonis has coordinated regional labs in Thailand and East Africa for the Duke University Comprehensive Antibody
Vaccine Immune Monitoring Consortium (CA - VIMC) funded by the Bill and Melinda Gates Foundation, and is a standing member of the HIV
Vaccines Study Section for the
Center for Scientific Review at the NIH.
As a member of the
Vaccine & Immunotherapy Center he studied accelerated vaccine development and targeted cancer therapies until Februar
Vaccine & Immunotherapy
Center he
studied accelerated
vaccine development and targeted cancer therapies until Februar
vaccine development and targeted cancer therapies until February 2015.
A phase 2
study of the therapeutic
vaccine is currently underway in other
centers in patients with recurrent disease to see if it can help extend 12 - month survival.
Its Clinical Trials
Center conducts 13 - 15 clinical
studies per year, and in December initiated a Phase 2 clinical trial of an Ebola
vaccine following its groundbreaking first - in - human testing of the Ebola
vaccine that showed efficacy in Guinea last year.
These
studies were sponsored by the
Vaccine Research
Center (VRC), NIAID, NIH.
Padmanee Sharma, M.D., Ph.D., a member of the CRI / Ludwig Cancer
Vaccine Collaborative (CVC) at The University of Texas MD Anderson Cancer
Center, has conducted innovative
studies testing the effects of anti-CTLA-4 checkpoint blockade in the pre-surgical setting.
Researchers in
Vaccine Research
Center (VRC) of the National Institute of Allergy and Infectious Diseases conducted this
study.
The products used in the trial were tested in the U.S. prior to the launch of the
study in Uganda and were developed by the
Vaccine Research
Center (VRC) at the National Institute of Allergy and Infectious Diseases (NIAID).
Hundreds of volunteers at the
Vaccine Center's Hope Clinic took part in this
study.
«Our work sheds light on the nature of CD32 as a molecule associated with transcriptionally active HIV and proves that targeting CD32 - positive cells is unlikely to hit the HIV latent reservoir,» said Mohamed Abdel - Mohsen, Ph.D., assistant professor in The Wistar Institute
Vaccine & Immunotherapy
Center and first author of the
study.
«Now that we know that [the difference] exists, it contributes to our understanding of why the
vaccine is not effective in all cases and informs future
vaccine development efforts,» said Dr. Dan Neafsey, associate director of the Genomic
Center for Infectious Diseases at the Broad and co-first author of the
study.
Silvestri's colleagues on this
study include Maud Mavigner, PhD, Yerkes and Emory
Vaccine Center, Ann Chahroudi, MD, PhD, Emory University School of Medicine (EUSOM) Department of Pediatrics, and Leslie Kean, MD, PhD, and Benjamin Watkins, MD, EUSOM Department of Surgery.
This
vaccine prototype is today being
studied by Cancer
Center researchers in clinical trials for kidney, prostate, and pancreatic cancers.
«This
study allowed us to evaluate the protective efficacy of several prime - boost
vaccine combinations, and these data will help guide the advancement of the most promising candidates into clinical trials,» noted lead author Dr. Dan Barouch of Beth Israel Deaconess Medical
Center at Harvard Medical School and the Ragon Institute of MGH, MIT, and Harvard.
Now that I am part of a
Vaccine Research Center (VRC) vaccine study, it enhances that altruistic feeling even more, knowing that my participation may someday save millions of
Vaccine Research
Center (VRC)
vaccine study, it enhances that altruistic feeling even more, knowing that my participation may someday save millions of
vaccine study, it enhances that altruistic feeling even more, knowing that my participation may someday save millions of lives.
The nanoparticle
vaccine technology used in the
study has been licensed by Parvus Therapeutics, Inc., a biotechnology company arising from the University Technology International LP, the technology transfer and commercialization
center for the University of Calgary.
Although there are no clinical
studies proving its efficacy, Dr. Matthew Brennecke, a board certified naturopathic doctor practicing at the Rocky Mountain Wellness
Center in Fort Collins, Colo., told Medical Daily in an email, «A common theory is that honey acts like a natural
vaccine.»
«This is an important
study that highlights the ability of even a modest
vaccine to substantially save lives during flu season,» said Dr. Amesh Adalja, a senior scholar with the Johns Hopkins
Center for Health Security.
Genetic
Vaccine Helps Immune System Researchers Dr. H. Kim Lyerly and Eli Gilboa from Duke University's Center for Genetic and Cellular Therapies in Durham, NC, are studying the safety and effectiveness of a new immune system therapy called a genetic v
Vaccine Helps Immune System Researchers Dr. H. Kim Lyerly and Eli Gilboa from Duke University's
Center for Genetic and Cellular Therapies in Durham, NC, are
studying the safety and effectiveness of a new immune system therapy called a genetic
vaccinevaccine.
There is some compelling evidence coming from a
study conducted at The
Center for Companion Animal
Studies at Colorado State University that shows that the common FVRCP (feline viral rhinotracheitis, calicivirus and paneleukopenia)
vaccine may cause long - term damage to cats» kidneys that increases with every booster.