Sentences with phrase «very large scale studies»

Very large scale studies with hundreds to thousands of children have determined that trajectories of physical aggression typically increase up through age 3, then decline.23 Although the greater aggression in males was to be expected, 24 the overall anger intensity and aggression severity in these patients with GD3 appear to be considerably greater than normal and significantly affect quality of life for them and their parents.

«This is a very large scale study using a new, innovative statistical method,» said study co-senior author Kenneth S. Kendler, M.D., professor of psychiatry, and human and molecular genetics in the Virginia Commonwealth University School of Medicine, and an internationally recognized psychiatric geneticist.

In a very large scale study in Denmark involving over 50,000 adults between the ages of 50 — 64 years, intake of oats has been associated with decreased risk of heart attack (also known as myocardial infarct, or MI).

Not exact matches

The results of this large - scale study are very reassuring as they confirm that current NICE guidance1, which recommends annual mammograms for women over 40 who are at an increased risk of breast cancer, is effective.

A groundbreaking 2016 paper, one of the first to conduct a large - scale analysis of shrinking mountain glaciers around the globe, concluded that all but one of the 37 studied sites were «very likely» retreating because of climate change — and at 21 of those sites, the influence of climate change was just about certain.

Tornado environment In the grand scheme of the atmosphere, tornadoes are small - scale, transient features, which makes them very difficult to predict, even within just a few hours, and to study within a larger climate context.

However, the very large - scale data collection for this study made it necessary to prioritize species for specific parts of the tree.

Moreover, such large trees are very useful for future studies of large - scale evolutionary patterns, such as how early placental mammals dispersed across the continents via land bridges that no longer exist today.»

Professor Jeremy Pearson, Associate Medical Director at the BHF, which part - funded the study, said: «By using the power of very large scale genetic studies, this research is the first to show that the known association between increased height and a lower risk of coronary heart disease is at least in part due to genetics, rather than purely down to nutrition or lifestyle factors.

The large - scale studies, most of which are made possible by the vast data generated and collected by new technologies like sensors and cellphones, are very good at describing the big picture, but don't provide much detail at the individual level.

Studies of human mobility usually focus on either the small scale — determining the origins, destinations and travel modes of individuals» daily commutes — or the very large scale, such as using air - travel patterns to track the spread of epidemics over time.

This tool can even initiate data processing immediately following an instrument run and complete it without user intervention — features that are very important in large - scale studies.

«We wanted to see whether very - large - scale screening across a diverse collection of cancer cell lines and a large number of drugs could yield new combinations for patients with cancer,» says Adam Friedman, MD, PhD, of the CBRC and the MGH Cancer Center, who led the study.

«The fact that this relationship was established in a large - scale, clinical human study is very important,» Przybelski says, «but there's still a lot we don't know.»

Very recently, a rather limited number of retrospective studies, utilizing whole genome sequencing (Talkowski et al., 2012) or whole exome sequencing (WES) in small cohorts of neonates and aborted fetuses with various ultrasound and / or post-mortem structural abnormalities (Carss et al., 2014; Drury et al., 2015; Alamillo et al., 2015; Westerfield et al., 2015), provided initial proof - of - principle of large - scale prenatal next generation sequencing (NGS).

According to a feasibility study conducted by the National Nuclear Laboratory, there is a very significant global market need for energy that can not, in all circumstances, be met by large scale nuclear reactors and so presents a real opportunity for SMRs.

Very little is known about the large - scale brain networks that may underlie the cognitive and behavioral symptoms of FXS.To identify large - scale, resting - state networks in FXS that differ from control individuals matched on age, IQ, and severity of behavioral and cognitive symptoms.Cross - sectional, in vivo neuroimaging study conducted in an academic medical center.

While this danger hasn't been looked at in any large - scale studies, dermatologists report finding more skin cancer on the fingers (typically a very rare location) of patients who have frequent exposure to these nail - drying lights.

What the Saul Zaentz Charitable Foundation has done is unique and inspirational — it is enabling the launch of a very large - scale study with the potential to generate insights akin to what the field of public health has produced, because of population - based research, around pressing issues, such as heart disease and the impact of smoking or lead exposure on health and development.

Earlier this year, the first large - scale international study to assess the financial literacy of 15 - year - old students showed, overall, Australian teenagers performed very well (Thomson, 2014).

We have many people inquire about natural oils especially in cats — I have many Vets also that have inquired about our various ingredients including NEEM oil — and after we explain that less then 1 / 100th of the formulation is made up of any of our essential oils they are very pleased with the concentration — especially when in our recommended usage less then 1 / 3rd of a teaspoon is recommended in very small breed dogs and cats — now take 1 / 100th of that and when it is used daily for the first 30 days on serious conditions with a topical application, and then the maintenance phase is one application every 3 to 4 days — the actual amount of any of our essential oils is very very small — and to add to the safety issue as I mentioned earlier it is a topical application and yes some is ingested — but with approximately 700,000 bottles used — and not one reported case of injury or death we have a fantastic record when compared to anesthesia scaling — according to the statistics reported in a very large study of 2,500 dogs — going under anesthesia — if the same 700,000 using our product chose anesthesia scaling instead according to the study — 2,358 would have died and 12 % or another 60,000 would have been injured!!!

The large - scale piece looks very different from the study, however.

We find (i) measurements at all scales show that official inventories consistently underestimate actual CH4 [methane] emissions, with the natural gas and oil sectors as important contributors; (ii) many independent experiments suggest that a small number of «super-emitters» could be responsible for a large fraction of leakage; (iii) recent regional atmospheric studies with very high emissions rates are unlikely to be representative of typical natural gas system leakage rates; and (iv) assessments using 100 - year impact indicators show system - wide leakage is unlikely to be large enough to negate climate benefits of coal - to - natural gas substitution.

WES programme manager David Langston said: «This study will inform the debate of whether development at very large scale is desirable or necessary to achieve commercially viable energy generation.»

«Rigorous processes» may help avoid a hockey - stick fiasco, but there are still two very basic problems: a) the proxy data themselves are often dicey, especially when the time scale is large, and b) the interpretation of the data is based on an «argument from ignorance» (i.e. «we can only explain this if we assume...»), where unknown factors are simply ignored and it is falsely assumed that we have the knowledge of all factors that could possibly have been involved; if these studies are used to provide evidence for a preconceived hypothesis, I think they are next to worthless.

the UHI effect is not pervasive, as all global - scale studies indicate it is a very small component of large - scale averages.

Both these studies note that various factors have contributed to climate change since the 1960s but that most of the recent large - scale warming was very likely due to the observed increase in greenhouse gas concentrations.

Some of these findings have been replicated across dozens of samples in very large international studies, in representative samples of entire national populations, and in large scale meta - analyses, such as the robust sex differences reliably - observed in studies of extramarital sexual behavior and permissive attitudes toward casual sex (Lippa, 2009; Petersen & Hyde, 2010).

Recently, a large - scale, longitudinal study investigating the CBT, GET, adaptive pacing therapy (APT) and specialist medical care (SMC) which had very low drop - out rates, found that CBT and GET (when added to SMC) were moderately effective outpatient treatments for this patient group as opposed to APT or SMC alone.6