Sentences with phrase «viral immunopathology»
Dr. Lohman - Payne's area of research is viral immunopathology, with special interest in the impact of HIV exposure in...
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They found that IL - 27 levels in infected lungs follow, with some delay, the level of virus: they peak as viral levels are starting to decline and come down when immunopathology has resolved.
The scientists conclude that in mice «well - timed treatment with rIL - 27 improved lung injury and accelerated recovery without affecting viral clearance» and continue «these data demonstrate that IL - 27 has a unique role in controlling immunopathology without impacting on host defense, and might therefore represent a promising candidate for immunomodulatory therapy of viral pneumonia.»
In this regard, animal model studies with FIPV in cats and RSV in mice have indicated that viral surface proteins may be the sensitizing protein of inactivated vaccines for immunopathology with infection [32], [45].
To differentiate between vaccines, three vaccine preparations were simultaneously evaluated, the double - inactivated (formalin and UV) whole virus vaccine (DIV), the rDNA - expressed S protein vaccine (SV), and the previously evaluated chimeric viral - like particle vaccine (VLP) that had led to immunopathology with virus challenge [16], [17], [20].