Even before
the WHI results came in, many women were looking for something different to relieve hot flashes, night sweats, and vaginal dryness.
The WHI results were published in JAMA in 2002 and 2004.
But manypro - estrogen physicians were unconvinced by the negative
WHI results, andthey've been reanalyzing the data.
Not exact matches
The 2002
WHI report in JAMA, which described early
results of the combined hormone therapy, shocked the medical community.
In 2004, researchers published
results of the
WHI study of estrogen - only therapy, taken for about seven years by women who had had their uteruses surgically removed.
Related sites Press release about the WISDOM steering committee's recommendation to continue the study The Medical Research Council More information about the
WHI study and the reasons it was stopped JAMA paper describing the
results from WISDOM
Related sites Press release about the decision to continue WISDOM More information about the
WHI study and the reasons it was stopped JAMA paper describing the
results from WISDOM
The
WHI could not address the risk of death due to breast cancer because with the relatively short follow - up time, few women in the
WHI have thus far died as a
result of breast cancer (3 in the active treatment group and 2 in the placebo group).
On the basis of HERS and other secondary prevention trials, the American Heart Association recommended against initiating postmenopausal hormones for the secondary prevention of cardiovascular disease.43 The American Heart Association made no firm recommendation for primary prevention while awaiting the
results from randomized clinical trials such as
WHI, and stated that continuation of the treatment should be considered on the basis of established noncoronary benefits and risks, possible coronary benefits and risks, and patient preference.
The
WHI trial
results provide the first definitive data on which to base treatment recommendations for healthy postmenopausal women with an intact uterus.
Still, mainstream medicine ignored the evidence until the Women's Health Initiative (
WHI) study was halted and
results released in the summer of 2002, showed that synthetic HRT definitively increases the risk of breast cancer.
(13) Immediately after this
WHI study was published in JAMA in 2002, there was a massive switch by women to bio-identical hormones which
resulted in a 4 billion dollar loss for Wyeth, the maker of Prempro ™.
When the Women's Health Initiative (
WHI) released
results from its follow - up study of women who quit hormone replacement therapy (see our previous article), not everyone got the message straight.
Q: Do the
results of the
WHI apply to your recommendations of using natural estrogen and progesterone?
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