This video will summarize principles of Morris
Water Maze testing review procedures for setting up and running the test and highlight some ways that this and other water tests are used in lab studies.
We want you to have software that fits the bill for all of these, from straight - forward protocols such as open field or Morris
water maze testing, to high - throughput testing, such as zebrafish larvae activity monitoring in 96 - well plates.
The research was done with laboratory mice that consumed different diets and then faced a variety of tests, such as
water maze testing, to monitor changes in their mental and physical function, and associated impacts on various types of bacteria.
Indeed, when mice lacking the gene for making IL - 4 take
the water maze test, they do badly, perhaps because their T cells lack a critical signal involved in fast learning.
At 14 months, however, the J20 / caspase -2 null mice did significantly better in
the water maze test than the J20 mice and similarly to the normal mice.
In
the water maze test, the mice needed to elevate themselves onto a platform in a specific location to get out of the water.
Mice were administered the Morris
water maze test in an opaque pool with a submerged platform, and humans were administered a virtual version in a circular field with a buried treasure using a 30 - in.
in 22 degree water there is increased latency of acquisition of the hidden platform in the Morris
water maze test
Not exact matches
This intellectual boost was demonstrated by the enhanced performance of the mice during
tests requiring them to navigate a
water maze and distinguish between known and unknown objects.
Subsequent analyses of the brains of these animals revealed that the drug reduced the plaques and tangles in the hippocampus, which is known to play a key role in learning the
water maze, but not in the amygdala, which figures importantly in the dark chamber
test.
Cohen subjected the mice to a learning
test known as the Morris
water maze.
Afterward, he compares the mental abilities of injured and uninjured rats by
testing their reactions to novel and familiar objects (top) and by placing them in a
water maze (bottom).
They compared the animals» ability to negotiate a radial - arm
water maze, a standard
test of cognitive ability, with that of regular J20 mice and of normal mice at 4, 9, and 14 months of age.
The scientists confirmed that these mice have learning problems by
testing them in a Morris
water maze, a common lab
test of animal learning and memory.
The creatures performed better on standard
tests of those skills, including swimming a
water maze, researchers at the University of Wisconsin reported.
A cost - effective solution for all standard behavioral
tests such as the Morris
water maze and open field
testing.
The PD model animals did prove to exhibit substantial
water maze deficits, both in time to locate the hidden platform and in time spent in the target quadrant on the probe
test.
The capacity of learning and memory was assessed by Morris
water maze (MWM)
test, and long - term potentiation (LTP) was determined to evaluate hippocampal neuronal plasticity at the end of
First, behavioral
tests like the
water maze are extremely useful for studying the molecular biology of learning and memory.
By two hippocampal - dependent memory
tests, the Morris
water maze and contextual fear conditioning, rivastigmine improved the memory
The difference in results obtained in the two tasks designed to
test reference memory (cross
maze and
water maze) indicated that the disturbance depended on task difficulty rather than on a particular memory component.
The beneficial effects of olibanum on memory deficit induced by hypothyroidism in adult rats
tested in Morris
water maze.
At this latter time point, all groups presented similar performance in cognitive
tests (Morris
water maze and inhibitory avoidance).