Sentences with phrase «when cells in culture»

When cells in culture are exposed to ionizing radiation, even those not directly hit sustain damage to chromosomes.

Not exact matches

In my cell biology course, we investigate the biology and chemistry of a cell surface receptor that helps induce good feelings in us when it binds to a chemical compound found in incense; this may help explain why so many different cultures and religions have independently evolved the use of incense in their ceremonies and ritualIn my cell biology course, we investigate the biology and chemistry of a cell surface receptor that helps induce good feelings in us when it binds to a chemical compound found in incense; this may help explain why so many different cultures and religions have independently evolved the use of incense in their ceremonies and ritualin us when it binds to a chemical compound found in incense; this may help explain why so many different cultures and religions have independently evolved the use of incense in their ceremonies and ritualin incense; this may help explain why so many different cultures and religions have independently evolved the use of incense in their ceremonies and ritualin their ceremonies and rituals.

Researchers hope the organoids will be better than lab animals or cells growing in culture at revealing how the human brain develops, both normally and when things go awry, and identify potential therapeutic or genome - editing targets.

«When someone has a problem — whether they need to find a particular cell line or need to understand the formulation of a particular type of culture medium — they're coming to you and they're in a crisis.

When these cultured cells were exposed to an air / liquid interface in the laboratory, they stratified, generating what the authors referred to as a multi-layered, «skin - like organoid.»

When tested in cultured cells, the compound specifically activated chaperone - mediated autophagy without touching other pathways.

Finally, in cell cultures and animals, overexpressing the hormone could produce something that looks like cancer, and that would shrink when treated with an IGF - 1R blocker.

When added to the cultured cells at molar ratios 103 to 104 times that of the luteinizing hormone releasing factor, both analogs decrease the amount of luteinizing hormone secreted in response to the releasing factor.

The team found several hundred that might do so and restore the protein to its functional shape; more than 30 did the job when tested in cell culture, although they don't know whether they attached to p53 in the pocket.

Upon expression in cultured cells, the new subunits yielded prominent, typical glutamate - and NMDA - activated currents only when they were in heteromeric configurations with NR1.

«It might be possible to grow these cells in culture then bank them so that if or when the mother develops some disease later in life, such as diabetes, her cells may be defrosted and differentiated into pancreatic beta cells,» says Lyle Armstrong of Newcastle University, UK, although he too, cautions that more tests are needed to determine exactly what these cells are.

In other experiments, the protein blocked the virus from infecting cells in culture, and it even prevented mice from getting sick when administered either 1 day before or after viral exposure, they report today in Nature BiotechnologIn other experiments, the protein blocked the virus from infecting cells in culture, and it even prevented mice from getting sick when administered either 1 day before or after viral exposure, they report today in Nature Biotechnologin culture, and it even prevented mice from getting sick when administered either 1 day before or after viral exposure, they report today in Nature Biotechnologin Nature Biotechnology.

When the Stanford team measured pyrophosphate levels in cultured cells derived from ank and normal mice, they found that the chemical accumulated in cells from the ank mice but decreased in the culture medium.

When cells that produced IL - 21 were put in culture with synovial fibroblasts (which are the main contributors to joint inflammation in rheumatoid arthritis), they induced the production of proinflammatory cytokines by these synovial fibroblasts, and cells that do not produce IL - 21, did not demonstrate this same outcome.

In 2009, from experiments at the RIKEN Center for Developmental Biology in Kobe, Japan, he found that when culture conditions are right, adding a single ingredient — bone morphogenetic protein 4 (Bmp4)-- with precise timing is enough to convert embryonic cells to PGCIn 2009, from experiments at the RIKEN Center for Developmental Biology in Kobe, Japan, he found that when culture conditions are right, adding a single ingredient — bone morphogenetic protein 4 (Bmp4)-- with precise timing is enough to convert embryonic cells to PGCin Kobe, Japan, he found that when culture conditions are right, adding a single ingredient — bone morphogenetic protein 4 (Bmp4)-- with precise timing is enough to convert embryonic cells to PGCs.

They found that when IGF - 1 was added to the cultured blood cells there was increased lithium sensitivity only in the blood cells of those bipolar disorder patients who did not respond to lithium therapy.

These structural changes can be mimicked, when the cells are maintained in culture, by application of serotonin, an endogenous facilitating neurotransmitter in Aplysia.

Even when ALL cells made up 40 percent of the cell mixture being cultured, they were entirely eliminated in 26 days of culture.

When they mixed the two types of cells in a culture, only one type of cell mingled.

You can look for efficacy in cell cultures, but that tells you almost nothing about what's going to happen when you test in a mouse or a human.

By lowering the oxygen in the culture — adding nitrogen to cut it by more than half — the researchers found they could dramatically improve the percentage of stem cells capable of making normal sperm when put back into the testes.

The researchers ran numerous experiments in cell cultures and mice to observe what happened to Salmonella in the inflamed gut when these genes were mutated.

Results suggest that cells grown in the device exhibit more natural behaviors than when grown in traditional culturing methods, and the filtration by the glomerulus is necessary for healthy cell function.

When the researchers applied some of these cultures to mouse colon cells in the lab dish, the cells were stimulated to release PYY hormone.

Prior research with cultured tissue had shown that a mix of chemicals could change bone marrow stem cells from mice to those resembling brain cells, but when a team led by neurologist Lorraine Iacovitti of Thomas Jefferson University in Philadelphia tried the same brew on human cells, the number altered was modest.

They showed in previous studies with cell cultures that when adding RK - 33 to malignant lung and other cancerous cells that highly express DDX3, proliferation slowed or halted, and the cells» ability to form colonies was impaired.

When the team blocked the activity of L1CAM in cultured human colon cancer cells, the cells» growth slowed dramatically.

When the researchers used gene engineering techniques to knock out DDX3 expression in laboratory - grown cell cultures that highly expressed this protein, cell proliferation was half that of cell cultures with high DDX3 expression.

In the monkey, when we tried injecting 20 or 30 laboratory - cultured pluripotent stem cells, nothing happened.

Moreover, when induced to differentiate into amastigotes extracellularly, in host cell - free culture, the parasites with reduced LMIT1 function showed incomplete differentiation and severe defects in iron content and iron - dependent mitochondrial metabolism.

By comparing hippocampal and cortical neurons in mono - culture (with other cells of the same type) and in co-culture (both cell types deposited within one device), the research showed that some features from hippocampal cells, like the percentage of action potential spikes found in bursts, were significantly higher when cultured together with cortical cells.

Kass developed the midstream urine test (still used when you pee in a cup) and set a numerical cutoff for the number of bacteria in normal urine: not more than 100,000 colony - forming units (cell clusters on a culture dish) per milliliter of urine.

For instance, when they added mosquito saliva containing sporozoites to cultured mouse liver cells, 10 % to 30 % of the cells showed signs of punched membranes, the team reports in the 5 January issue of Science.

When applied to immune cells in culture, the compounds decreased the cells» production of the inflammatory signal IL - 22 and increased production of anti-inflammatory IL - 12.

When they applied a heparanase blocker to similar lesions produced in cell and tissue culture, they healed quickly and completely.

When applied to neurons in cell culture, the antibody locked onto a protein on the cell surface.

When he genetically disabled or chemically modified the HSPGs in cell cultures and in a mouse model, clumps of tau could not enter cells, thus inhibiting the spread of misfolded tau from cell to cell.

Furthermore, genes that are lethal when knocked out in embryos can be analyzed with RNAi in cell culture.

They have spread lies about his methods, accused him of electrocuting monkeys when in fact he was working with cells in culture dishes, and limited his job opportunities.

Normally, CD4 cells will start dividing when they are treated with certain proteins in a culture dish.

When they knocked two of these genes out of the bacterium's genome, it couldn't survive in a lab culture of immune cells, they report in the 26 May issue of Science.

When they put human macrophages in the lower compartment filled with cell culture medium, the cells rose toward the membrane.

And when the researchers simulated starvation in cultured mouse liver cells, the cells also ramped up SIRT1 production; when they added glucose, cells ramped it down.

When the researchers turned off SIRT1 genes in cultured cells, the cells secreted less than half as much glucose as unaltered cells.

Another, previously unknown gene — when the investigators worked out its protein's structure and studied it in tissue culture — proved to do just the opposite: The protein helped the schizont leave the infected blood cell.

To find out, he engineered cells in culture to contain either the heat - or cold - sensitive TRP receptors, which when triggered change the biochemistry of the cell in a measurable way.

When the researchers deliberately blocked the gene's activity in cultured breast cells by adding RNA sequences that bound to BRCA1 mRNA, preventing it making protein, they found that the cells began to divide rapidly, just like malignant cells.

When BMP protein was added for three days in human pluripotent stem cell - derived gut tube cultures, it induced a posterior HOX code.

Further, when TILs have been used for such purposes, the proportion of what Harari calls the «juiciest» T cells — those recognizing mutations on cancer cells — tends to decline significantly when the cells are expanded in culture.

When scientists figured out how to culture animal cells in the early 1900s, some claimed such cells would let us live forever.