When genes change in response to their environment, it's called evolution.
Not exact matches
When genes spontaneously
change, or mutate, they produce different traits.
By Lauren Kearney You may have first seen
Gene Baur
when he was featured talking about how not eating animal products
changed his life in the inspirational pro-vegan film, Forks Over Knives.
Such methods include cell fusion, microencapsulation and macroencapsulation, and recombinant DNA technology (including
gene deletion,
gene doubling, introducing a foreign
gene, and
changing the positions of
genes when achieved by recombinant DNA technology).»
Kids can't
change the
genes that will determine how tall they will be or
when puberty starts.
«Some people are protected from the effects of sleep deprivation by this particular
gene variation but, for most of us, sleep loss does something to the brain that simply prevents us from switching gears
when circumstances
change.»
«Our research shows this particular
gene influences a person's ability to mentally
change direction
when given new information,» Van Dongen said.
Porcar's team engineered
gene switches in Escherichia coli to produce proteins that emit different coloured fluorescent light
when factors such as heat, acidity and oxygen levels
change.
«In addition,
changes in how the
genes are expressed (turned on or off) could be used in the future to predict how and
when the cancer cells will spread to other parts of the body and how fast they will grow.»
The overlap in
gene expression
changes when neural progenitor cells are infected by African or Asian strains of Zika virus.
The two - step process of TILT — getting sick upon toxicant exposure and failing to get well — may be driven by epigenetic
changes, which occur
when the environment alters the expression of
genes without
changing the core DNA code itself.
Finally, the team identified a network of
genes in these regions that exhibit
changes in expression
when the normal boost from serotonin is lacking, and these
changes depended on how long the drug was given.
When pandas changed diets the Tas1r1 gene became obsolete and, without it, they might not have wanted to eat meat even when it became plenti
When pandas
changed diets the Tas1r1
gene became obsolete and, without it, they might not have wanted to eat meat even
when it became plenti
when it became plentiful.
And
when asked about the possibility of
gene editing giving babies a much reduced risk of serious disease, some 49 % of adults say this would be less acceptable if it
changed the genetic makeup of the whole population.
Vogelstein, Kenneth Kinzler, and other colleagues found a minor
change in the APC
gene, which normally holds cell growth in check and can cause colon cancers
when mutated.
However, the downside comes
when the inevitable accumulation of mutations takes its toll, or
changes to the environment make
gene combinations less well suited than they had once been.
When Orlando and colleagues examined horse DNA for
genes that may have rapidly
changed during domestication, they too found
genes involved in neural crest cell function.
When produced in excess during times of adversity, these particular miRNAs trigger epigenetic
changes, which alter
gene activity to cope with these environmental hardships.
When pathogens infect the cells of the body, the infection sets off a chain reaction involving the immune system that
changes the activity, or expression, of hundreds of
genes.
Marine mussels brave their constantly
changing environment by switching on and off
genes so they can perform necessary life tasks
when its best to do so.
When his team looked at
gene expression
changes in the mice, then applied them to humans with early stage cancer, the results revealed a breakdown of which patients have a high or low chance of survival.
The axiom, «growing like a weed,» takes on new meaning in light of
changes in
gene expression that occur
when weeds interact with the crops they infest, according to plant scientist Sharon Clay.
These modifications, known as «epigenetic»
changes, help determine how and
when genes are used.
«We found sets of
genes in young birds whose levels
change when they sing, and are linked to learning,» said White, who is also a member of UCLA's Brain Research Institute.
Curious about the possibility of circular RNAs contributing to cancer, Pandolfi and his colleagues set out to see if they could detect relevant
changes in tumors known to harbor distinct fusion proteins, which result
when different chromosomes abnormally join together, melding two separate
genes into a new centaur - like
gene.
When Bordenstein and Brucker compared
gene expression patterns in normal and microbe - free offspring, they found significant
changes in many of the
genes involved in the immune response (Science, doi.org/m87).
Steve: The
changes were in those other sequences that determine how those
genes get expressed,
when they get turned on and off and in what numbers.
Global warming has
changed the
genes that tell pitcher plant mosquito larva (inset)
when to hibernate in the winter.
She hopes to pinpoint which
genes are expressed in each cell type
when brain cells make long distance connections, and to make similar maps in other primates to chart what
changed as brains rewired over the course of evolution.
This same feature, tumor heterogeneity, may reduce the ability to identify critical
gene expression
changes when comparing mean
gene expression in adjacent tumor and normal tissues, as tumors of the same type may have different sets of
genes differentially expressed.
Cell receptors will receive a signal from outside, and
when it binds, that information is transmitted through the receptor to other proteins within the cell, [creating] a chain of events to
change how the
gene works in the cell.
If the living conditions
change, say
when the temperature drops or the lipid composition
changes, then a different lipid uptake
gene adapted to that condition sets in.
When this protein is damaged or missing, it
changes the activity of multiple
genes and causes Rett syndrome, a disorder marked by developmental delays, seizures and autism - like behaviors.
If so, it could make cell fate more resilient to random mutations in a plant's genetic code, even
when such
changes keep some
gene - regulating proteins from binding their intended DNA targets.
When the researchers subjected adolescent mice with the
gene mutation to either social stress or caloric restriction, but not both, the animals exhibited little
change in feeding behavior.
When two copies of the altered hemoglobin
gene are present, they cause the shape of the hemoglobin to
change so much that the «sickled» blood cells don't flow freely in the blood vessels, causing excruciating pain.
But
when they disrupted the clock mechanism by inhibiting the responsible
genes, the periodically
changing variations in the lipids were mostly lost.
Although it was first seen in the 1940s to be the evolutionary glue that held species together, and thus a significant evolutionary force, a few decades later
when quantitative data on
gene flow in plant populations began being collected, this view
changed as evidence seemed to indicate that
gene flow was not all that significant.
«
When you domesticate animals, you tend to
change genes in that system,» he says.
This matters
when diagnosing leukaemia, where overexpression of
genes makes the cell's genome
change shape.
«
When we looked at
gene expression, we found fairly small
changes in 65 million years of the macaque, orangutan and chimpanzee evolution,» Gilad explains.»
When they experience a big shift in temperature, they
change the
genes that are expressed in the cell.
When studying how normal cells
change into cancer cells, dos Santos and other cancer researchers pay close attention to
gene expression.
Silent mutations occur
when the
change of a single DNA nucleotide within a protein - coding portion of a
gene does not affect the sequence of amino acids that make up the
gene's protein.
When Pollin and her colleagues sequenced the
gene in their Amish volunteers, they found a mutation that matched with those who had lower triglycerides to start with and whose blood levels
changed relatively little after drinking the milkshake.
To work out the genetic basis, Duke University postdoctoral associate Bob Fitak and biology professor Sönke Johnsen and colleagues investigated
changes in
gene expression that take place across the rainbow trout genome
when the animal's magnetic sense is disrupted.
The immunotherapy drug pembrolizumab,
when combined with chemotherapy, doubles survival in patients with non-squamous non-small cell lung cancer (NSNSCLC) lacking genetic
changes in the EGFR or ALK
genes,
when compared to...
When the researchers looked at the role of
genes that were methylated by
genes with code differences related to ASD, including additional
genes beyond those with direct code
changes, they found that the majority were involved in biological pathways that were important in immune function.
The NIH Common Fund's Library of Integrated Network - based Cellular Signatures (LINCS) program aims to create a network - based understanding of biology by cataloging
changes in
gene expression and other cellular processes that occur
when cells are exposed to a variety of perturbing agents.
The majority of that specialization is governed by epigenetic
changes — histone modifications, DNA accessibility, and methylation — that influence
when and how
genes are expressed.