Sentences with phrase «when lung tumors»

Not exact matches

However, the impact of the two methylation - regulating enzymes was still seen at 10 to 15 months, when scientists found decreased expression of hundreds of genes — many of which are key tumor suppressor genes such as BMP3, SFRP2 and GATA4 — in the smoke - exposed cells and a five - or - more-fold increase in the signaling of the KRAS oncogene that is known to be mutated in smoking - related lung cancers.

«We found that many more mice developed tumors when given the cells that we had engineered to have these stem cell characteristics, and they had a much higher incidence of metastasis in the lungs,» Kilian said.

When the researchers removed FAK from blood vessels that grew in melanoma or lung cancer models, both chemotherapy and radiation therapies were far more effective in killing the tumors.

«Historically, when treating early lung cancer with radiotherapy, progression at the site of the primary tumor was the most common failure resulting in suffering and death,» said lead study author Robert Timmerman, MD, professor and vice chair of the department of radiation oncology at the University of Texas Southwestern Medical Center in Dallas.

When the researchers administered daily doses of BCX to mice before and after they injected the rodents with a nicotine - derived carcinogen, they found that the mice treated with BCX had fewer lung tumors than those that got no BCX.

When they blocked IKK2 activity in the mice with lung cancer, the mice had smaller tumors and lived longer, suggesting that the enzyme is necessary for NF - KB to stimulate tumor growth.

A new study shows that tumor suppressor PTEN helps fight lung infections when attached to a protein that is mutated in cystic fibrosis.

These interests grew from studies of paraneoplastic neurologic disorders (PNDs), a group of diseases thought to arise when tumors — typically breast, ovarian, or lung cancers — start making proteins normally only made by the brain.

In this study, human lung cancer cells with additional copies of the opioid receptor grew more than twice as fast as tumor cells that lacked extra receptors when transplanted into mice.

The lung tumors were likely metastatic sequelae of an oral tumor that they found when they looked in his mouth.

The disseminated disease occurs when tumor cells spread beyond the local lymph nodes to the lung, liver, spleen, gastrointestinal system, eyes, central nervous system, skin, muscles, bone and / or the bone marrow.

We opted not to go the route of chemo and radiation when she was diagnosed with a primary lung tumor at age 16.

When the tumor has already spread some pets might have difficulty breathing (dyspnea) due to buildup of the tumor in the lungs, or lameness due to spread of the tumor to the bones.

Regional lymph node metastasis is uncommon (5 - 10 %) Non-tonsillar SCC is the least likely of the oral tumors to metastasize to the lungs (10 %), and when found in dogs, have the most favorable prognosis when located in the rostral (front) portion of the oral cavity.

When new tumors showed up in Clea's lungs, he referred Clea to an American trained board certified small animal internal medicine specialist at his clinic, Dr. Suzy Valentin.

Although when first discovered, most dogs with OSA have «clean» thoracic radiographs (chest X-rays), there are usually tumor cells present in the lungs, but the masses are too small to be seen in routine radiographs.

Hacking coughs in old dogs and cats are also common when tumors are present in their lungs.

A few dogs are diagnosed with advanced metastasis (tumors that have spread to elsewhere in the body, such as the lungs and lymph nodes) and might be feeling ill from their tumors when they come for treatment.