Sentences with phrase «when tumour cells»

When a tumour cells escapes from the liver to travel towards the lung, it releases more PTHLH, thus further stimulating the process.

When a tumour cell is located, the antibody binds to the cell surface and releases the caged radioisotope into the tumour cell.

Not exact matches

When placed at the site of a cancerous tumour in a rodent and «activated» by a scope with a light source, the compounds eradicated up to 100 % of cancer cells.

The AR - V7 variant is formed when an androgen receptor loses the end part of the receptor, called the C - terminal end; this is deleted due to an error in RNA processing in tumour cells, leaving only the beginning part of the receptor, the N - terminal end.

Only cancer cells that received these growth factors switched on this pathway, and only they could seed new tumours when injected into mice.

«We would hope to create little protein factories in the tumour cell that are only switched on when the cells are hypoxic,» says Kingsman.

When chlorotoxin is tagged with a fluorescent dye, it will illuminate a tumour — a trick that makes the surgeon's job easier by helping to pinpoint cancerous growth and ensure that all the cancerous cells are removed and healthy tissue spared.

To get into the blood vessels, the cell needs to penetrate tissue, both when it leaves the tumour and when it is attaching to a new organ.

A more highly publicised case was in 2009, when an Israeli teenager developed brain and spinal tumours after receiving several implants of fetal stem cells in Moscow to treat a rare degenerative condition.

When The Cancer Genome Atlas Research Network reported its genomic profiling of clear - cell kidney tumours, about one - quarter of participants (126 patients) had been operated on at Memorial Sloan Kettering3.

In addition, they showed for the first time that these genes are often the same as those that are altered in breast tumours - when a tumour develops, the DNA within the cancer cells themselves mutates.

Such secondary tumours are formed when individual cells break away from the main tumour and travel through the bloodstream to distant areas of the body.

This unfortunate and rare side effect of the biopsy provided Nicola Valeri at the Institute of Cancer Research in London and his colleagues with a kind of stopwatch — an exact point in time when a few cells left as the needle was withdrawn began their two year evolution into a tumour.

When cancer cells from eg breast or lung tumours invade the bones through metastasis, the bone tissue is degraded.

When the researchers eliminated the expression of this gene in the CAFs, these cells behaved like normal fibroblasts, as they lost the ability to help the tumour cells to progress.

When tumours are treated with drugs, some resistant cancer cells can survive and continue to grow, leading to disease relapse.

Mutations in a gene that helps regulate when genes are switched on and off in cells have been found to cause rare cases of Wilms tumour, the most common kidney cancer occurring in children.

When they loaded sperm cells with doxorubicin, a common chemo agent, and released them in a dish containing mini cervical cancer tumours, the sperm swam towards the tumours, killing 87 per cent of their cells within three days.

When cancer cells interact with the walls of the blood vessels, EPHA2 is activated and the tumour cells remain inside the blood vessels.

When they injected the soil bacterium Clostridium [ck] novyi into the bloodstream of mice with tumours, it spread throughout the necrotic region, consuming living tumour cells as well as dead tissue.

When the EPHA2 is inactive, the tumour cells can push out and spread.

When the antibody binds to a tumour cell, it activates the internal receptor, triggering the CAR T - cell to attack the attached cancer cell.

Understanding the processes that restrain mutant cells from developing into tumours, and how they are breached when cancers do form will guide the development of strategies to reduce the chance of cancer development in individuals who have acquired a high level of mutations.

Neural stem cells have this remarkable ability to continuously self - renew and it seems brain tumour stem cells are exploiting some of the same molecular programs when they multiply, though in a very corrupted way.

Recent evidence indicates that non-cancerous support cells within tumours, referred to as the stroma are emerging as key sources of tumour - promoting inflammation, but little is known how or when in tumour evolution these functions are acquired.

When components of the TGFβ signalling pathway, e.g. Smad 2 and / or 4 are mutated, cell proliferation is uncontrolled and can lead to the development of cancerous tumours.

When normal cells turn into tumour cells, some of the antigens on their surface change.

We identify 23 genes that, when disrupted in mouse, modify the ability of tumour cells to establish metastatic foci, with 19 of these genes not previously demonstrated to play a role in host control of metastasis.

The Journal of Agricultural and Food Chemistry had on its December 2006 issue a report that found the ability of red raspberries to repress the human oral and breast, as well as colon and prostate tumour cell lines growths when they were tested in test tubes.