Sentences with phrase «when zebrafish»

When zebrafish are infected with Mycobacterium marinum (blue), immune cells (red) quickly surround the bacteria to form tightly organized nuggets called granulomas.

When zebrafish with the green fluorescing endothelial gene matured, the researchers observed green FGPs on the surface of the fish's brains — confirming that these cells arose from endothelial tissue.

Not exact matches

Testing the titanium sub-oxides on zebrafish (the aquatic cousin of lab rats) showed it to be toxic when ingested; the toxicity was significant in tissue not exposed to sunlight.

Zebrafish that stop swimming when left without company are showing promise as the first fish model of a human mood disorder.

That allows her to image the cells of awake, moving creatures, such as the flashing neurons of crawling fly larvae or the beating hearts of twitching zebrafish, without the problem of blurring when the animal moves.

In 2005, when neurobiologist Herwig Baier of the University of California, San Francisco, was screening thousands of zebrafish for vision problems, he found one that seemed a bit «off.»

When the scientists inserted human colorectal cancer cells into zebrafish embryos and allowed them to grow for 4 days, the resulting tumors showed three hallmarks of human solid tumors: rapid cell division, formation of blood vessels to supply nutrients, and the ability to spread to other locations in the body.

When the researchers applied a human form of Ctgf protein to lesions in zebrafish, they observed similar recovery of spinal cord function, hinting that other factors within zebrafish spinal tissue may explain the healing differences between mammals and zebrafish.

The canines get around a huge hurdle that mice, zebrafish, and other organisms present when researchers try to recapitulate human disease.

In a study performed by North Carolina State University researchers, zebrafish that were bred to be more bold — quantified by the shorter amount of time they remained motionless when placed in new surroundings — displayed a sleeker body shape and an ability to dart around the water more quickly when startled than those bred to be more shy.

In the study, the researchers used zebrafish lines that had been selected to be bolder by breeding fish that stayed still for a maximum of 50 seconds after being introduced into new surroundings, while shy fish — those that stayed still for more than 3 minutes when dropped into a new area — were bred to create a shy line.

When Kaufman, Zon and colleagues looked to see what was different about these early cancer cells, they found that crestin and the other activated genes are the same ones turned on during zebrafish embryonic development — specifically, in the stem cells that give rise to the pigment cells known as melanocytes, within a structure called the neural crest.

Finally, they demonstrated that zebrafish OPCs differentiate into mature oligodendrocytes when cultured together with human motor neurons, differentiated from induced pluripotent stem cells.

When the scientists prevented the genes from working in zebrafish, they failed to develop fingerlike projections called fin rays — the fishes» «hands.»

And the zebrafish, which is transparent when it is young and so lets researchers watch its organs grow, will probably be next in line.

When a substance is bound to zebrafish Abcb4, this triggers cleavage of the energy transfer substance adenosine triphosphate (ATP).

To test whether this affects the early heart, Hove's team used small beads to block blood flow in the zebrafish heart at 37 hours, when the heart is little more than a tube.

The mutations may also change skin color by blocking yellow pigments: When the researchers knocked out MFSD12 in zebrafish and mice, red and yellow pigments were lost, and the mice's light brown coats turned gray.

When he infected zebrafish with bright blue Mycobacterium marinum, he saw bright red immune cells quickly surround the bacteria to form tightly organized granulomas.

A synthetic form of the snail insulin, when injected into zebrafish, caused blood glucose levels to plummet.

When the scientists broke up cell huddles in their zebrafish embryos, FGF leaked out.

Zebrafish larvae readily absorb compounds from the surrounding water, which is a great advantage when it comes to determining the effects of certain drugs or other substances.

In particular we are interested to unravel the mechanisms that ensure the maintenance of the apical membrane when exposed to physical stress, e. g. during morphogenesis of epithelial tissues, or when exposed to light stress in photoreceptor cells, using Drosophila and zebrafish as model organisms.

Specifically, the following predictions are expected to be met: i) fish attraction toward the robotic fish should vary as the visual cues offered by the robotic fish are varied, in agreement with similar observations for zebrafish in [35]--[37]; ii) fish attraction should vary as a function of the robotic fish tail - beat frequency, as suggested in [60] and observed in [20]; and iii) the highest attraction should be reached when both visual and flow cues from the live fish are simultaneously integrated in the robotic fish prototype.

In zebrafish, injection of low doses of both Tuba and Cdc42 antisense morpholinos, which had no effect when administered separately, led to severe phenotypes similar to those seen following knockdown of other ciliary proteins.

The big boost to the zebrafish field came when two big genetic screens searching for mutants were carried out in the early 1990s.

She saw that cells of older zebrafish embryos didn't glow much when they were exposed to water the December 2014 and June 2015 stormwater, meaning the cells weren't very active.

When the one of these lincRNA, called megamind, is reduced in zebrafish, the embryos have abnormally shaped heads and enlarged brain ventricles, as indicated by the arrow.

In a report published on September 30 in Nature Genetics, Katsanis and his team used a small transparent fish, zebrafish, to literally watch what happened if they chemically blocked the production of three proteins that are required for primary cilia function during the period when a fish egg develops into a grown up, fully - finned fish.