Sentences with phrase «while environmental factors»

While some environmental factors can be used to provide early identification of at - risk individuals, others can possibly be counteracted by education, training, or interventions.

About 80 % of the susceptibility to develop an autoimmune thyroid disease (AITD) is attributed to genetic factors, while environmental factors contribute to 20 %.

While environmental factors have an impact on your chances of developing this disease, so do genetics.

While environmental factors play a role in developing T2D, it is also highly heritable — and the genetics involved are complex, with many genes contributing to disease risk.

Earlier this year, scientists examining more than two million births in Sweden reported that inherited genes make up about 50 percent of a child's autism risk, while environmental factors make up the other half.

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

While the Canada Pension Plan Investment Board also considers environmental, social and governance factors when making investments, much of the CPP's equity portfolio essentially replicates major stock indexes.

Such risks, uncertainties and other factors include, without limitation: (1) the effect of economic conditions in the industries and markets in which United Technologies and Rockwell Collins operate in the U.S. and globally and any changes therein, including financial market conditions, fluctuations in commodity prices, interest rates and foreign currency exchange rates, levels of end market demand in construction and in both the commercial and defense segments of the aerospace industry, levels of air travel, financial condition of commercial airlines, the impact of weather conditions and natural disasters and the financial condition of our customers and suppliers; (2) challenges in the development, production, delivery, support, performance and realization of the anticipated benefits of advanced technologies and new products and services; (3) the scope, nature, impact or timing of acquisition and divestiture or restructuring activity, including the pending acquisition of Rockwell Collins, including among other things integration of acquired businesses into United Technologies» existing businesses and realization of synergies and opportunities for growth and innovation; (4) future timing and levels of indebtedness, including indebtedness expected to be incurred by United Technologies in connection with the pending Rockwell Collins acquisition, and capital spending and research and development spending, including in connection with the pending Rockwell Collins acquisition; (5) future availability of credit and factors that may affect such availability, including credit market conditions and our capital structure; (6) the timing and scope of future repurchases of United Technologies» common stock, which may be suspended at any time due to various factors, including market conditions and the level of other investing activities and uses of cash, including in connection with the proposed acquisition of Rockwell; (7) delays and disruption in delivery of materials and services from suppliers; (8) company and customer - directed cost reduction efforts and restructuring costs and savings and other consequences thereof; (9) new business and investment opportunities; (10) our ability to realize the intended benefits of organizational changes; (11) the anticipated benefits of diversification and balance of operations across product lines, regions and industries; (12) the outcome of legal proceedings, investigations and other contingencies; (13) pension plan assumptions and future contributions; (14) the impact of the negotiation of collective bargaining agreements and labor disputes; (15) the effect of changes in political conditions in the U.S. and other countries in which United Technologies and Rockwell Collins operate, including the effect of changes in U.S. trade policies or the U.K.'s pending withdrawal from the EU, on general market conditions, global trade policies and currency exchange rates in the near term and beyond; (16) the effect of changes in tax (including U.S. tax reform enacted on December 22, 2017, which is commonly referred to as the Tax Cuts and Jobs Act of 2017), environmental, regulatory (including among other things import / export) and other laws and regulations in the U.S. and other countries in which United Technologies and Rockwell Collins operate; (17) the ability of United Technologies and Rockwell Collins to receive the required regulatory approvals (and the risk that such approvals may result in the imposition of conditions that could adversely affect the combined company or the expected benefits of the merger) and to satisfy the other conditions to the closing of the pending acquisition on a timely basis or at all; (18) the occurrence of events that may give rise to a right of one or both of United Technologies or Rockwell Collins to terminate the merger agreement, including in circumstances that might require Rockwell Collins to pay a termination fee of $ 695 million to United Technologies or $ 50 million of expense reimbursement; (19) negative effects of the announcement or the completion of the merger on the market price of United Technologies» and / or Rockwell Collins» common stock and / or on their respective financial performance; (20) risks related to Rockwell Collins and United Technologies being restricted in their operation of their businesses while the merger agreement is in effect; (21) risks relating to the value of the United Technologies» shares to be issued in connection with the pending Rockwell acquisition, significant merger costs and / or unknown liabilities; (22) risks associated with third party contracts containing consent and / or other provisions that may be triggered by the Rockwell merger agreement; (23) risks associated with merger - related litigation or appraisal proceedings; and (24) the ability of United Technologies and Rockwell Collins, or the combined company, to retain and hire key personnel.

This woman and her Fascist Right wing Nazis need to sit in prison for their crimes against humanity because I am not the only one these cold blooded lying murders did this to, and they deliberately will not have anyone obey Court Orders and get me Medical Records together, and get me Medical Doctors to address my Medical Concerns, and get all my Doctors on the same page, because they intended all along on messing up my Medical records while causing me serious medical harm, and then letting me die from Medical Neglect so that they could falsely blame me or environmental factors and they even have the Police deliberate to refuse to investigate why they removed Tests from my Medical Records that showed the harm that they caused.

When it comes to sustainability, factors such as responsible sourcing and ethical farming practices were just as important as environmental factors to consumers, while some also equated organic and non-GMO with health, added Kerry.

While some of these factors, such as food safety concerns and technological innovations, are unpredictable in magnitude and timing, others are observable (e.g. income growth), constrained by supply side factors (e.g. lack of feed) and determined by institutional changes (e.g. harmonization of standards) and policies (e.g. agricultural subsidies and environmental regulations).

Diagnoses of attention deficit disorder are at an all - time high, and while the exact cause for each case may not be possible to specify just yet, new evidence suggests environmental toxins are a contributing factor to ADD and ADHD, or attention deficit hyperactive disorder.

And while we know that the development of food allergies is a highly complex mix of both genetic and environmental factors, decreasing that risk would mean less children at risk for anaphylaxis and more parents able to breathe a little bit easier whenever they send their children off to school or to a birthday party.

Super Soft Lotion leaves skin soft while providing a protective layer of natural antioxidants to shield skin from environmental factors

While this ranking focused more on environmental factors (our does not), Huggies Little Movers diapers were the highest ranking mainstream brand on its list.

While social and environmental objectives are not necessarily in conflict (indeed action to meet green objectives through domestic heating and insulation improvements represents the definitive policy in eradicating fuel poverty), a range of factors mean that they are nevertheless often seen as competing for political priority and resources.

According to a 2013 study of California farmers, factors like exposure to extreme weather events and perceived changes in water availability made farmers more likely to believe in climate change, while negative experiences with environmental policies can make farmers less likely to believe that climate change is occurring, said Meredith Niles, a postdoctoral research fellow at Harvard's Sustainability Science Program and lead author of the study.

Kirby, in contrast, feels that while the idea of thimerosal as the «one and only cause of autism has gone out the window,» he still believes there is an «epidemic» with many environmental triggers and with thimerosal as a possible contributing factor.

Now, a team of researchers including Elie Bou - Zeid an associate professor of civil and environmental engineering at Princeton who experienced the storm while in Lebanon, have found a more likely cause for the unprecedented storm — it was not human conflict, but a combination of climatic factors and unusual weather.

Multiple research projects have shown that about half of the variation in people's body mass index can be attributed to genetic factors, while the rest is due to environmental factors, including diet and exercise.

While it has been generally accepted that exposure to harmful environmental factors increase the susceptibility of the brain to neurological and psychiatric disorders, new types of environmental agents are continuingly added to the mix, requiring evolving studies, Hasimoto - Torii says.

While they don't know whether the first group of students would have shown a shift in attitudes after the storms, the researchers believe their findings provide evidence that personal experience is one factor that can influence instinctive attitudes toward environmental policy.

While the excess risk found in celiac first - degree relatives can be explained by genetics, the higher risk in spouses points to the impact of environmental factors.

While the cause of bloat is unclear, there is a strong predisposition in some dogs and it is generally thought that GDV is influenced by both genetic and environmental factors.

While researchers know that adolescent drinking is influenced by both genetic and environmental factors, much less is known about interactions between the two.

While environmental issues are often cited as a major factor in cities and towns in pursuing sustainability, a new study shows that economic concerns can be just as important to local governments in adopting concrete sustainability plans.

Dr Fairchild commented: «If impaired facial emotion recognition is a risk factor for Conduct Disorder, further research is needed to determine why some relatives with similar genetic and environmental risk factors might develop Conduct Disorder while others remain unaffected, despite exhibiting similar problems in emotion recognition.»

While the affection's causes are not yet known, scientists believe that they consist of both genetic and environmental factors.

In his latest research, Li also has found that environmental factors more likely determine how much money proactive employees earn, while genetics more likely determine a proactive employee's job satisfaction.

While many environmental risk factors exist, including high blood pressure and smoking, stroke risk is also frequently inherited.

All told, about 20 % of the distribution of domesticated species across the Amazon seemed to be driven by human influences, while 30 % was likely due to environmental factors such as soil composition.

While researchers think there is a genetic component to autism, they also believe environmental factors are playing a role in its recent increase.

And while lifestyle or environmental risks for patients don't seem to explain the difference in live disease in men and women who have hepatitis B, those factors aren't meaningless, either.

While certain diseases have a clear genetic cause, many conditions are the result of a complex mix of genetic and environmental factors.

Studying the diseased cells in a controlled environment allows scientists to test environmental factors and drugs on the cells, while also gaining insight into how the neurons develop defects or dysfunction.

While identical twins have exactly the same genetic sequence, environmental factors lead to differences in how their DNA is methylated.

Moreover, risk factors may be different for different individuals - while one person may develop schizophrenia due largely to a strong family history of mental illness (e.g. a high level of genetic risk), someone else with much less genetic vulnerability may also develop the disease due to a more significant combination of prepregnancy factors, pregnancy stress, other prenatal factors, social stress, family stress or environmental factors that they experience during their childhood, teen or early adult years.

So while your genetics may increase your risk, keep in mind that so do various other environmental and lifestyle factors.

Some mutations may develop randomly over time, while others are inherited or may be the result of environmental exposures or lifestyle factors.

While you need the gene for the disease to be triggered, «there are other factors that facilitate the onset of celiac, one of which is environmental,» he says.

So, while we can't really affect our nature, or our genetics, we can affect how those genes are expressed and we can look at the environmental factors that might trigger those genes to be expressed.

While there are many lifestyle and environmental factors that lead to unwanted selenium deficiency, selenium toxicity is not desirable either.

(10) While genetics and environmental factors play a role in the development of cancers, researchers are just starting to understand the effects of free radicals in the development of cancer.

While high estrogen levels along with a lack of progesterone is a major factor the estrogen dominance seen in women with PCOS, environmental factors can also play a role.

If labs return showing that there is hypothyroidism, then also looking for deficiencies of selenium, iron, and zinc would be important next steps, while also looking for environmental factors that interfere with iodine utilization.

The unfortunate truth is that your body is being bombarded on a daily basis, and has been for years, by foods, environmental toxins, drinks, and other factors that are DESTROYING your body's natural ability to create Testosterone, while also keeping Estrogen levels in check.

Rice bran (Oryza sativa) beads provide natural exfoliation while protecting skin from environmental factors.

While a real food lifestyle is key to health and manageable weight loss, there are significant lifestyle and environmental factors that work against most people's timeline for healthy weight loss.

For example, some women with PCOS have more inflammation triggered by stress, environmental factors, or dietary choices while others are more prone to insulin - resistance.

All of the above and more while tackling the effects of climate change, pollution and other environmental factors that can harm and do harm people's health, livelihoods and lives.