Sentences with phrase «while mouse studies»

While the mouse study does not prove a direct connection between Zika infection and microcephaly, Rossi said, it does underscore the urgent need for effective animal models to further study the course of disease and its transmission.

However, before you jump right in to extended fasts, take note that human studies are often short term — observing Ramadan, for example, for a month — while mice studies span their entire lifetime.

Not exact matches

While we can't use sterile mice to make any definitive conclusions about humans, the twins study, published in the journal Science last year, provided clear evidence that the microbiome is involved in weight gain — something earlier research had only suggested.

While curcumin has been shown to prevent depression, reverse liver damage, and prevent and treat Alzheimer's, my mom can go ahead and unarch that eyebrow — the majority of the studies showing the dramatic results have only been done on mice and rats.

While study results indicated that combining capsaicin with the chemicals «might promote cancer cell survival,» the report clearly stated that the control group of mice treated only with capsaicin ``... did not induce any skin tumors...» In addition, the study repeatedly cited other research studies in which the anti-cancer properties of capsaicin were solidly demonstrated.

While our work has used mouse models because we can study the process in detail this way, we do know that milk cells cross into human babies as well.»

«This well - designed set of experiments shows that chronic THC pretreatment appears to restore a significant level of diminished cognitive performance in older mice, while corroborating the opposite effect among young mice,» wrote Susan Weiss, director of the Division of Extramural Research at the National Institute on Drug Abuse, who was not involved in the study, in an e-mail.

In this study, Dr. Dimitriou monitored spindle signals in humans while they learned to control the position of a visual cursor by moving their hand (much like using a computer mouse).

While the study used mice, COUP - TFII probably works the same way in other mammals, including humans, Donahoe says.

In the study, one group of pregnant mice got saline injections into the womb, while another group got injections of lipopolysaccharide (LPS), a toxin meant to generate the kind of inflammatory effects of E. coli bacteria without the presence of the germ itself.

Three groups of middle - aged mice (about a year old) were studied: one group ate a normal diet, in which fewer than 30 percent of calories came from fat, while two others were fed high - calorie diets in which 60 percent of the calories came from fat.

While mouse models have traditionally been used in studying the genetic disorder, Deng said the animal model is inadequate because the human brain is more complicated, and much of that complexity arises from astroglia cells, the star - shaped cells that play an important role in the physical structure of the brain as well as in the transmission of nerve impulses.

The potential strategy — which targets metabolic pathways that are active only during intestinal inflammation — prevented or reduced inflammation in a mouse model of colitis while exerting no obvious effect in control animals with healthy, balanced bacterial populations, said Dr. Sebastian Winter, Assistant Professor of Microbiology and co-corresponding author of the study published online today in Nature.

The researchers first stumbled onto this while studying how mouse antibodies act as catalysts.

In the current study, Dr. Xu and colleagues gave radiation therapy to a mouse model of human pancreatic cancer to eradicate the bulk tumors, while only the cancer stem cells remained in the residual scars.

While studying the inflammatory mechanisms underlying colitis in rodents, a team of researchers led by Dana Philpott and Thierry Mallevaey realized that their laboratory mice were more susceptible to developing the disease if their intestines were already infected with the protozoan Tritrichomonas muris.

A recent study published in Cell revealed that, while the related parasite Tritrichomonas musculis makes the intestine susceptible to both colitis and colorectal cancer, it induces an immune response that protects mice against Salmonella infection.

«While this study took place in mice, the work sets the scene to do early clinical trials in humans.

Studying aging and its associated diseases has been challenging because existing vertebrate models (e.g., mice) are relatively long lived, while short - lived invertebrate species (e.g., yeast and worms) lack key features present in humans.

A new University of Iowa study in mice shows that drug - induced changes to the gut microbiome can cause obesity by reducing the resting metabolic rate — the calories burned while sleeping or resting.

And while their study was performed in mice, the drug used has already been tested in clinical trials to treat other, unrelated conditions.

While the effects in mice are distinct from what happens in people with herpes, the study reveals a previously unrecognized disease process.

Now, a new study in mice shows that females vaccinated before pregnancy and infected with Zika virus while pregnant bear pups who show no trace of the virus.

While studying why some mice resist HSK, a team led by immunologist Harvey Cantor of Harvard Medical School in Boston found that possession of a particular variant of one type of antibody renders T cells incapable of attacking tissue in the cornea, the transparent covering of the iris and pupil.

While previous investigations into the protein's effects have used either mice in which gene expression was knocked out or transgenic animals that expressed human gene variants throughout their lifetimes, the MGH - MIND - led study used a different approach to investigate the effects of introducing the variant forms of the protein into brains in which plaque formation had already begun.

A new study in mice shows that females vaccinated before pregnancy and infected with Zika virus while pregnant bear pups who show no trace of the virus.

In its study, the research group used a male pheromone, secreted from the tear gland, called ESP1 that has been shown to enhance sexual behaviors in female mice, while promoting aggression in males exposed to ESP1 in conjunction with unfamiliar male urine.

While trying to create better mouse strains for studying human diseases, she and other researchers may have inadvertently stumbled upon genes that render hybrids as dead ends.

The findings are the culmination of years of investigation that were triggered when O'Banion and his colleagues made a surprising discovery while studying mouse models of Alzheimer's disease.

Previous proteomic studies in humans with brain injuries didn't control for the cause, while results in mice examined the effects of time since injury or repeated injury, but not both.

Among the study's key findings was that mice given lithium chloride after alcohol consumption and mice that never consumed alcohol had the same duration of undisrupted sleep of about 10 hours per day, while untreated mice given alcohol woke up as many as 50 times per hour.

«While our study was in mice — and with the caveat that we don't yet know whether Zika has the same effect in men — it does suggest that men might face low testosterone levels and low sperm counts after Zika infection, affecting their fertility.»

However, while psilocybin has been shown to affect the brains of mammals including mice, there is little evidence that it affects insects or other invertebrates — barring a famous 1962 study showing that it changes the way spiders build webs.

«What we found early on was not all mice will mate with each other,» says clinical psychologist Melissa Farmer, who led the study while earning her Ph.D. at McGill University in Montreal, Canada.

While the gene encoding the Y6 receptor is altered in man, Professor Herzog believes it would be unwise to ignore it because the development of anti-obesity drugs relies heavily on mouse studies.

Rolls studied laboratory mice that had been gently handled for four hours to prevent them from sleeping while their comrades dozed.

In this study, the researchers demonstrated that when normal mice were given kynurenine, they displayed depressive behaviour, while mice with increased levels of PGC - 1a1 in muscle were not affected.

While the research reported in this paper manipulated pluripotent mouse cells, the researchers have moved ahead in performing similar studies with human stem cells and achieved comparable types of results with the microparticle delivery approaches.

While earlier studies showed that mice lose their fear of bobcat urine for a few weeks after infection, Ingram showed that the three most common strains of Toxoplasma gondii make mice less fearful of cats for at least four months.

While it doesn't provide an easy cure for hair loss, the study does uncover a key component of the genetic wiring behind hair growth in both mice and men.

A treatment group of mice were given an intake of folic acid 20 times greater than the RDA for humans: while the folic acid dosage consumed by most adults is lower and taken over a longer period of time, a higher dose was used in this study to account for the fact that mice are more efficient in metabolizing folic acid than humans.

The mice in the original study were from an 8th generation backcross to the FVB line, thus it was on a mixed background, while the mice used in the replication will be from a pure 10th generation backcross to the FVB line.

Now, a study led by Brown University researchers has identified an enzyme that appears the regulate the physiology of both fat types in mice — decreasing inflammation in white fat tissue, while promoting the ability of brown fat to burn calories.

While the UC Riverside did not look at the toxicity of GO in their study, researchers at the Hersam group from Northwestern University did report in a paper published in the journal Nano Letters («Minimizing Oxidation and Stable Nanoscale Dispersion Improves the Biocompatibility of Graphene in the Lung») that GO was the most toxic form of graphene - based materials that were tested in mice lungs.

In a study of mice with symptoms that mimic early Alzheimer's disease, the researchers found that while the mice had trouble recalling memories, those memories still existed and could be optogenetically retrieved.

Even while these experiments were proceeding, Dr. Sumner wanted to study the phenomenon of HDAC inhibition in the SMA mouse.

Many similar approaches to disrupting the well - studied operations of growth hormone and insulin metabolism also extend life in mice to various degrees, some of which are whole - body, while others are tissue - specific.

The first meaning is usually intended in literature that deals with rats or mice, while the second meaning is usually intended in studies of human EEG recorded using electrodes glued to the scalp.

While studying the basic function of the IKK complex in zebrafish and mice, researchers at the Salk Institute for Biological Studies discovered that one subunit reigns in the activity of the other instead of boosting it, as was widely believed before.

He wanted to study the long - term effects of a ketogenic diet in mice, while addressing one of the major issues that crop up in research involving diet — variability.