Sentences with phrase «while normal mice»

The reason for Frizzled6 mice's messy hair soon became obvious: The mutant mice are born with hair follicles that point in random directions, while normal mice have follicles pointing more or less in the direction needed for the hair to lay flat.

At the advanced age of 20 to 22 months (roughly equivalent to 100 years in humans), the Bax - deficient mice still maintained hundreds of follicles while normal mice had none.

The cells immediately began sticking to blood vessel walls, while normal mice were unaffected.

When normal and gene - altered mice ate the high - fat diet — along with varying levels of doxycycline to induce GLP1 release — mice expressing GLP1 (left) gained less weight gain while normal mice (right) grew fat.

Not exact matches

The normal mice shed excess fat and reversed early signs of diabetes, while the mutants only lost fat (Nature, DOI: 10.1038 / nature10758).

Three groups of middle - aged mice (about a year old) were studied: one group ate a normal diet, in which fewer than 30 percent of calories came from fat, while two others were fed high - calorie diets in which 60 percent of the calories came from fat.

While 80 percent of normal mice are able to handle a temperature drop, all mice lacking ERRγ did not tolerate the cold.

They destroyed the T cells in 12 mice, five of which received marrow cells from normal mice while seven received marrow from mice with a defective Fas - ligand gene.

The hind paws of the normal mice became hypersensitive and blistered in response to the UVB exposure, while those of the mutant mice showed little sensitization and tissue injury.

One group consisted of normal mice, while the other group was genetically unresponsive to the hormone leptin, which promotes feelings of fullness after eating.

Photoswitches inserted into retinal ganglion cells (RGC) of blind mice produce much less variety of response (all evenly red means the cells fire at the same time), while blind mice with photoswitches inserted into bipolar cells (ON - BC driven) exhibit much more variety in their retinal response to light, closer to that of normal mice.

«While the «normal» mice exposed to stress exhibited high histamine levels and disease, the mice without CRF1 had low histamine levels, less disease and were protected against both types of stress,» Moeser said.

Some fell into a pattern of two to three separate cycles of sleep and activity per day, in contrast to the single daily cycle found in normal mice, while others» rhythms were completely disorganized, Blackshaw says.

Despite higher glycogen levels, glycogenin - deficient mice underperformed normal mice, reaching exhaustion earlier and covering a shorter distance while running on a treadmill.

Faustman got her idea by chance while transplanting islets, the pancreatic bodies that contain beta cells, from normal mice into others that had lost theirs to type 1, or juvenile, diabetes.

To test the effect of the change, Tsien and colleagues at the East China Normal University in Shanghai gave mice a slight shock in a training chamber while playing a loud tone.

With thoughts of a jolt fresh in their brain, mice with normal levels of α - CaMKII froze up when they returned to the chamber an hour later, while mice with boosted levels remained calm.

The genetically altered mice, however, had the same reaction when placed in the altered cages, while their normal compeers showed nary a trace of fear.

While these XX male mice had the same level of testosterone as normal XY mice, they displayed more masculine sexual behaviours — mounting females more often and ejaculating more frequently.

In this study, the researchers demonstrated that when normal mice were given kynurenine, they displayed depressive behaviour, while mice with increased levels of PGC - 1a1 in muscle were not affected.

While humanized mouse models for HIV infection have utility, the model is limited due to incomplete immune reconstitution, development of xenogeneic graft versus host disease (GVHD), and the absence of normal T cell homeostasis.

Left: The gut of a mouse that received a transplant of microbes from the gut of four - day - old normal mice, and then was exposed to Salmonella, while the other received a transplant of the four - day - old mouse microbes along with added Clostridia bacteria, before being exposed to Salmonella.

Statistically, about 25 percent of the mouse pups will inherit both copies of the knocked out gene, while their littermates will have only one copy and be heterozygous, or normal.

Mice that had been eating a ketogenic diet performed at least as well on memory tests at old age as they did at middle age, while mice eating the normal diet showed an expected age - associated declMice that had been eating a ketogenic diet performed at least as well on memory tests at old age as they did at middle age, while mice eating the normal diet showed an expected age - associated declmice eating the normal diet showed an expected age - associated decline.

It should be noted, however, that while a study on senescent cell ablation in genetically normal mice would provide at least some evidence on the effect of senescent cells (and their ablation) on promoting cancer, even such a study would likely show less effect than could be anticipated in a large mammal model, since even normally - aging mice rarely suffer metastatic disease to the extent of aging humans, as sheer primary tumor volume is generally sufficient to be fatal to mice.

Mice exposed to normal TB live for 161 days, while mice infected by bacteria that lack sigF lived for 246 days, according to findings that were reported in Infection and ImmunMice exposed to normal TB live for 161 days, while mice infected by bacteria that lack sigF lived for 246 days, according to findings that were reported in Infection and Immunmice infected by bacteria that lack sigF lived for 246 days, according to findings that were reported in Infection and Immunity.

Skeletal analysis of the mice deficient in MT1 or MT2 melatonin receptors showed a low bone mass in MT2 - / - mice while MT1 - / - mice had a normal bone mass compared to the WT mice.

Indeed, the inactivated form of GSK3β, pS9 - GSK3β, was readily detected by immunohistochemistry in caErbb2 - initiated early lesions in parous mice while it was not found in normal mammary cells (Figure 3E).

* Oddly enough, however, the experiments with fresh pancreatic islets and fat cells taken from the mice suggested that the positive effects of uncarboxylated osteocalcin on insulin only occurred at concentrations extremely low compared to those of undercarboxylated osteocalcin normally present in mice, while the effects on adiponectin and energy expenditure only occurred at normal to high concentrations.

this was the one thing with move that seemed to stand on its own... I don't mind the idea of HD wii sports either, as long as it really is 1:1... that was my only real complaint with the wii when it released... there was motion control, but it was gimmicky and registered «wiggles» into canned animations... not to mention the gamecube visuals... still not sold on Move though... for me to really want one, I want to see what they are doing with shooters... Socom 4 and killzone 3 could be very special for core gamers and motion controls if they are done right... if you can aim on screen in true 1:1 fashion while sitting comfortably at a «normal» gaming distance... it could rearrange how I play first person shooters on a console... developers are saying the Move has input latency of 21ms, which is roughly half of a DS3... and second only to a wired mouse / keyboard... need to see how it works though, as it is not always that simple... just saying that if it does what its supposed to... it could end up being the answer to shooters on a console... as much as I like playing shooters with 2 sticks... I can't argue that I miss the days of a mouse and keyboard (as well as PC being the only platform to get the best shooters on... no longer the case by any means)... but with a first person shooter, there is no wiggle room... pun intended... it has to register every mm of movement on screen... and do it quickly... not sure if it can yet...