Sentences with phrase «wide association study approach»

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Using an approach called a genome - wide association study, researchers scanned complete sets of DNA in thousands of participants, looking for small variations that appear more often in people with the disease than in healthy individuals.

«Our approach is likely to «revive» genome - wide association studies as a strategy to identify genetic risk factors and to develop novel treatment options for a wide range of diseases, just as people had hoped for when the genetic code was deciphered a decade ago.»

Another way of looking at genome - wide association study results is the so called pathway - based approach, which links SNPs considered mutually involved in a pathway.

First publication of genome - wide association study leveraging deCODE's population approach; Finding to be integrated into deCODE's DNA - based diagnostics program A team of deCODE scientists, along with academic colleagues from the United States, Iceland, Spain and the...

This discovery approach greatly enhances the future potential of epistasis analysis for systems biology, and can complement genome - wide association studies as a means of formulating hypotheses for targeted experimental work.

While FDR is a well - recognized approach in biology, one could also argue for using a family wise error rate (FWER), which has been the norm in recent large - scale, genome - wide association studies (GWAS).

While genome - wide association studies (GWAS) are an efficient approach for the identification of recessive alleles, they require several unrelated affected individuals [17]--[19].