Sentences with phrase «wild type alleles»

Wild type alleles in ancient samples are represented by yellow dots and derived alleles by red dots.

Not exact matches

As shown in Table 1, the presence of one or two Mstn mutant alleles in combination with the F66 transgene resulted in increasingly more muscle mass than seen in F66 transgenic mice that were wild type for Mstn.

Determining genetic disruption frequency by both the Cel1 and 454 assays require the assumption that wild type and disrupted alleles are not differentially amplified.

In transient transgenic reporter studies of zebrafish embryos, the +254 kb element holds up: the wild - type allele had enhancer activity in 41/82 embryos (50 %), whereas the mutant allele had enhancer activity in 3/83 embryos (3.6 %).

Both experiments showed that the wild - type allele had greater DNA - binding capacity, and drove higher expression of the reporter gene.

By comparing gene expression changes induced upon expression of wild - type and mutant alleles, we inferred the activity of specific alleles.

By injecting pairs of TALEN - encoding mRNAs into wild - type embryos, we generated the CCHa2 - RTAL - 34 frameshift allele (Figs 3B and S2B and S2C).

In cfDNA isolated from plasma after treatment resistance, at a local read depth of 968x, 459 reads (44 %) bore the wild - type allele.

The location and frequency of the p.K1872X / wild - type allele are noted in gold / blue.

At a local read depth of 200x, 48 DNA reads (24 %) bore the p.K1872X allele, whereas 38 reads (19 %) bore the wild - type allele.

Using quantitative PCR, we compared the levels of Hex transcript from the wild - type and transgenic alleles to those from the transgenic allele only.

In this scenario, if a locus i contains a drive element and the next locus does not, then the drive cuts both wild - type alleles at that locus until both copies are disrupted, rendering resulting gametes nonviable (ci = 1).

After three days, they tested each cell in every embryo to learn how many had two copies of the wild - type allele.

These human embryos almost always used the wild - type strand on the healthy allele to guide the repair, rather than the introduced ssODN.

There is no direct test for the Wild type (think wolf pattern) allele which is designated aw.Any dog which has at least one copy of Ay (and no KB) will be fawn or sable, either with or without brindling.Any dog that is «aa» (and no KB) will be black.

The Hairless allele (the wild type) is a dominant (and homozygous prenatal lethal) trait, while the Powderpuff allele acts as a simple recessive trait in its presence.