Sentences with phrase «with axonal transport»
Marsh - Armstrong, N., Oglesby, E., Buckingham, B., Horner, PJ., Soto, I. (2007) Molecular Changes in DBA / 2J Retinal Ganglion Cells Coinciding With Axonal Transport Dysfunction (Investigative Ophthalmology & Visual Science, 48: ARVO E-Abstract 5553).
https://www.glaucoma.org/ Not exact matches
When it is experimentally prevented (either by severing the projecting axons, by treating them with the drug vinblastine, which blocks axonal transport, or by administering 6 - hydroxydopamine, which destroys the nerve endings), the innervating sympathetic neurons in the ganglion die off.
Work in several laboratories has shown that the retrograde axonal transport of NGF follows its interaction with specific receptor sites on the nerve terminals of the newly established fibers.
The lethal effects of blocking the axonal transport of NGF can be completely overcome, however, by supplying the cell bodies with externally administered NGF.
In my laboratory, we hypothesize that age - dependent neuronal death occurs partly in response to the decline with age, of the process of axonal transport of those critical proteins that are needed for neuronal survival.
Aβ proteins, which build up to toxic levels in the brains of people with Alzheimer's disease, impair the axonal transport of these cargoes.
Furthermore, CRF - induced phosphorylation of tau protein interferes with neuronal energetics as it impairs axonal transport of mitochondria.»