Sentences with phrase «x syndrome»

Molecular biomarkers predictive of sertraline treatment response in young children with fragile X syndrome.

Inclusion criteria for the current study were: European Caucasian descent, IQ ≥ 80, no diagnosis of conduct disorder, autism, anxiety disorder, depression, epilepsy, general learning difficulties, neurological disorders or known genetic disorders (e.g. Fragile X syndrome, Down syndrome).

Parents raising children with ASD have been found to report higher levels of parenting stress, depression and anxiety, and increased general life stress than parents raising children with Down syndrome (DS), cerebral palsy (CP), fragile X syndrome (FXS), intellectual disability (ID), cystic fibrosis (CF) or typically developing (TD) children [e.g. 11, 12, 13, 14, 15, 16, 17].

The present study examined trajectories of adaptive behavior, behavior problems, psychological symptoms, and autism symptoms in adolescents and adults with fragile X syndrome (n = 147) over a three - year period.

For the past several years, she has worked at a therapeutic day school with children and adolescents with ADD, ADHD, Aspergers Syndrome, fragile X Syndrome, and developmental delays.

Epilepsy • Fragile X syndrome • High - functioning autism • Hyperlexia • Multiple - complex Developmental Disorder • Semantic pragmatic disorder • Nonverbal learning disorder

My graduate research explored alternative treatment use in children with ASD, intervention and supports for children with Fragile X Syndrome, and efficacy - based EI programs for young children with ASD.

I coordinated a national study exploring early childhood brain and behavioral development in children with autism, Fragile X Syndrome, and developmental delay.

Better Start This article on the Raising Children website has information about the Australian Government's Better Start for Children with Disability initiative, which funds early intervention services for children under six who have been diagnosed with a sight or hearing impairment, including deafblindness, Down syndrome, cerebral palsy, or Fragile X syndrome.

Commonly, studies have compared an overall measure of stress between parents of children with autistic disorder to those of parents of children with typical development [31]- [34] or those diagnosed with Down Syndrome, intellectual disability, and Fragile X syndrome [15][16][19][35]- [38].

Dick Hebdige, recentMitchell Center Visiting Scholar, is a cultural critic who was invited to the campus for a series of three multimedia lecture performances, including the riveting X Syndrome: Vertigo and Autobiography, an intensely «personal» narrative about an ascent into and out ofmadness.

This condition pertains to the fragile X syndrome among human beings.

My younger son has multiple disabilities stemming from a genetic mutation called Fragile X Syndrome.

She lectures extensively throughout the U.S. as well as internationally, on behavioral and educational interventions for children with neurodevelopmental disorders primarily those with fragile X syndrome.

Jonah has a genetic mutation called Fragile X Syndrome which can cause a constellation of impairments, particularly in males (who, unlike females, don't have a compensatory backup X chromosome.)

Patients with Alzheimer's disease, Fragile X syndrome, Down syndrome, and autism are particularly susceptible to seizures, 12 and the focus of much research at the Waisman Center of Developmental Disabilities has been on the myriad ways drugs, diet and genetic manipulation can affect amyloid beta levels, seizure threshold and behavioral phenotypes.13 In an editorial entitled «Concocting the Right Diet for Brain Health» published December 2011 in Translational Medicine, Dr. Westmark expressed concern about the risks of soy: «The prevailing view is soy is healthy, but much remains to be learned regarding its effects on brain development and function.»

«High exposure to estrogenic compounds during fetal and early childhood development through soy - based food products could disrupt the function of the natural steroid hormones and contribute to the high incidence of seizures associated with many childhood, neurological disorders including autism and FXS (Fragile X Syndrome).

STX209 shows some promise in its ability to reduce social withdrawal, a key symptom of fragile X syndrome.

In addition to fragile X syndrome, my laboratory also has conducted studies to determine whether the signaling cascades that normally are required for long - lasting synaptic plasticity and memory are altered in mouse models of several developmental disorders, iincluding autism spectrum disorder (ASD), intellectual disability (ID), tuberous sclerosis complex (TSC), and Angelman syndrome.

The drug, called STX209 or arbaclofen, is one of the first designed to treat the molecular changes in the brain caused by fragile X syndrome.

Gross, C., Chang, C. - W., Kelly, S.M., Bhattacharya, A., McBride, S.M.J., Molinaro, G., Raj, N., Allen, A.G., Whyte, A.J., Danielson, S.W., Jiang, M.Q., Chan, C. - B., Ye, K., Gibson, J.R., Klann, E., Jongens, T.A., Moberg, K.H., Gourley, S.L., Huber, K.M., and Bassell, G.J. (2015) Increased expression of the PI3K enhancer PIKE mediates deficits in synaptic plasticity and behavior in fragile X syndrome.

11:30 AM ATR - X syndrome: How defects of a chromatin remodeler lead to alpha thalassemia.

Since 2011, as an associate professor at Stanford University, I have led a team focused on synaptic changes occurring during normal and pathological behaviors (sleep, fragile X syndrome, ASD) as well as eye / brain neuronal regeneration.

Santini E, Huynh TN, Longo F, Koo SY, Mojica E, D'Andrea L, Bagni C, Klann E. (2017) Reducing eIF4E - eIF4G interactions restores the balance between protein synthesis and actin dynamics in fragile X syndrome model mice.Sci Signal.

A normal version of the FMR1 gene sequence, where the fragile X syndrome can develop, contains 5 - 55 nucleotide (CGG) repeats.

The team was also able to reverse the abnormal electrical activity associated with the fragile X syndrome.

Fragile X syndrome (FXS) is an X-linked neurogenetic disorder characterized by a cognitive and behavioral phenotype resembling features of autism spectrum disorder.

The most common form of intellectual impairment in men is known as the fragile X syndrome and affects 1 out of 3,600 boys.

Fragile X syndrome (FraX), the most common heritable cause of developmental disability, is associated with IQ, memory, and visuospatial processing deficits.

The team produced the first evidence that removing methylation, which are molecular tags that keep a mutant gene shut off, can reactivate the gene and restore the fragile X syndrome neurons.

The healthy control mice take three or four sessions; the mice engineered to mimic Fragile X syndrome can take nearly twice as long.

Scientists at the Whitehead Institute used CRISPR / Cas9 gene editing method to restore activity to the fragile X syndrome gene in affected neurons.

She uses induced pluripotent stem cells to study Fragile X syndrome, a common genetic cause of autism and intellectual disability.

Recent work in fragile X syndrome suggests aberrant fronto - striatal and fronto - parietal networks and relates these abnormalities «forward» to behavior and «backward» to decreased protein expression.As the field of neuroimaging has matured, it has revealed its promise as a safe, reliable, in - vivo tool in the study of developmental disorders.

Goel, raised in Bangalore, India, has focused in particular on Fragile X syndrome, a genetic disorder that can occur along with autism and is thought to be the genetic cause of autism in patients with Fragile X syndrome.

Francesco Longo is interested in understanding the synaptic and behavioral abnormalities associated with autism spectrum disorder, with particular attention to striatal dysfunction in fragile X syndrome model mice.

E. Korb et al. «Excess Translation of Epigenetic Regulators Contributes to Fragile X Syndrome and Is Alleviated by Bd4 Inhibition,» Cell 170 (September 7, 2017): 1209 - 1223.

A third endeavor is raising hopes for the first drug treatment to relieve learning, memory, social and behavioral problems associated with fragile X syndrome, a genetic condition that shares features with autism.

His lab develops isogenic human pluripotent stem cells and transgenic animals to model disease, with the goal of delineating novel approaches to influence outcomes for Huntington disease (HD) and Fragile X Syndrome (FXS), the most common genetic causes of dementia and intellectual disability, respectively.

ScienceDaily «A human stem cell line derived from embryos that were identified by preimplantation genetic diagnosis (PGD) to carry the mutation for fragile X syndrome has...

Cell biology chair Gary Bassell was interested in the disease, because it's a triplet repeat disorder, similar to fragile X syndrome, yet the CNS mechanisms and symptoms are very different.

FMRP is also the protein that is missing in Fragile X Syndrome, the leading single - gene cause of autism and intellectual disability.

Homeostatic Responses Fail to Correct Defective Amygdala Inhibitory Circuit Maturation in Fragile X Syndrome.

For example, the genetic disorder Fragile X syndrome — a common cause of both mental retardation and autism, directly affects the production of Arc in neurons.

The story of Samuel, a young boy diagnosed with Fragile X syndrome participating in a clinical trial at Emory.

Inhibitors of Histone Deacetylases Are Weak Activators of theFMR1Gene in Fragile X Syndrome Cell Lines.

This process is important for the study of several neurological diseases such as fragile X syndrome, for example.

Fragile X syndrome — the most common heritable cause of autism spectrum disorder — is something of a phantom.

Fragile X syndrome occurs when a mutation prevents the gene from making adequate amounts of FMRP.

«Fragile X syndrome: Early detection important.»