Sentences with phrase «zebrafish research»
The zebrafish is now a well - established model system whereas zebrafish research was mere small fry as recently as the 1990s.
https://www.yourgenome.org/
Although zebrafish research began in the 1960s, it is only since the 1990s / 2000s that it has shot to prominence.
10:10 - 10:30 Petronella Kettunen, Sahlgrenska Academy, Institute of Neuroscience and Physiology Imaging methods in zebrafish research and applications
In addition to Wingert, authors include Poureetezadi, Christina N. Cheng, Joseph M. Chambers and Bridgette E. Drummond, graduate students in her laboratory, the Center for Stem Cells and Regenerative Medicine and the Center for Zebrafish Research.
The zebrafish research was led by Camila Esguerra of the Laboratory for Molecular Biodiscovery of University of Leuven (Leuven, Belgium).
Not exact matches
«We knew that the brain hat was a very high potential» among marchers, says Chris Pierret, a biologist at the Mayo Clinic in Rochester, but his group commissioned crocheted zebrafish hats, honoring one of their favorite disease research models.
In the initial stages of the research project, Yaniv's team members Julian Nicenboim and Dr. Guy Malkinson obtained images of developing zebrafish embryos, whose transparent bodies make it possible to document embryonic development in real time over several days.
The scientists hope their findings on cell migration in zebrafish will open up new perspectives for research on proteins that control metastasis and thus the malignancy of cancer.
The projects are guiding research in mice, zebrafish and fruitflies, with the goal of unpicking the mechanisms of mental disorders.
She commented: «Our previous research to validate zebrafish as a model for epilepsy put us in a good position to be able to help the EuroEPINOMICS consortium investigate the function of CHD2.
If you actually read the paper that launched a thousand offbeat tidbits, by one Emmanuel Mignot of Stanford University, you discover that those «mutant» zebrafish with the defective genes were engineered to be mutants, in bulk, purely for the purpose of research.
The protein itself has been known to researchers for some time as a result of research on zebrafish, where it plays an important role in the healing process following damage to the spinal cord.
Having spent his first 5 years in that position establishing his own research theme and tools to study zebrafish development, «now it is thanks to this programme that I can expand and fully develop it.»
Photo of a living Brainbow zebrafish, taken by Zachary Tobias (a research technician in Weissman - Unni's lab), showing a brightly labeled neuron with its cell body (white) at bottom.
Research in the laboratory of Rebecca Wingert, the Gallagher Family Associate Professor of Adult Stem Cell Research in the Department of Biological Sciences at the University of Notre Dame, has confirmed the key role of a certain small molecule in the development of kidney structures in zebrafish, a widely used model for human kidneys.
«Using models such as zebrafish and neonatal mice that regenerate their hearts naturally, we can begin to identify important molecules that enhance heart repair,» said Ellen Lien, PhD, of The Saban Research Institute of Children's Hospital Los Angeles.
«In order to be able to research more closely what effect PSENEN has, we, in collaboration with Prof. Odermatt, deactivated the gene in some zebrafish larvae and then compared these with normal larvae under the microscope,» explains Damian Ralser.
As a next step, Dr. Reimer's research team intend to analyse the effect of different drugs on zebrafish OPCs in order to potentially identify a method to improve functional spinal cord repair in humans.
«The research carried out in zebrafish unit of the University of Helsinki showed that in addition to cell cultures, these optogenetic tools worked also in living tissues,» says Academy Research Fellow Jarresearch carried out in zebrafish unit of the University of Helsinki showed that in addition to cell cultures, these optogenetic tools worked also in living tissues,» says Academy Research Fellow JarResearch Fellow Jari Rossi.
«Right now success rates for grant applications are about 23 percent, which is not bad in an international context,» says Joan Heath, a zebrafish researcher at the Parkville Branch of the Ludwig Institute for Cancer Research in Melbourne, Australia.
Zebrafish have emerged as an important vertebrate model for cardiovascular research for a number of reasons, including the ability to regenerate its heart if damaged, and because the transparency of the embryos allows easy observation of internal processes like blood vessel development.
New research from a team including Carnegie's Daniel Gorelick and Marnie Halpern on the effects of these chemicals on zebrafish shows that embryonic heart valves could be particularly in danger.
The next steps for the research group are to use what they have learned from this zebrafish model of gut inflammation to design better probiotics to treat intestinal inflammation.
The ability to grow a new limb may seem like something straight out of science fiction, but new research shows exactly how animals like salamanders and zebrafish perform this stunning feat — and how humans may share the biological machinery that lets them do it.
But research by others has shown that zebrafish scales are more related to the musculoskeletal system, rather than the tissues that form teeth.
Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim, together with U.S. colleagues, have now observed in the embryo of the zebrafish that muscle cells migrate from the undamaged atrium into the ventricle and thus significantly contribute to regeneration.
The zebrafish is used as a model organism for research into the embryonic development of vertebrates.
«Epilepsy drug discovered in fish model shows promise in small pediatric clinical trial: Research suggests zebrafish models may be efficient resource for identifying drugs for clinical use.»
Genetic modification in zebrafish models is cheap and easy, so authors point out that future research on these animal models will contribute to understand the molecular relationship that exists between the proteins involved in the physiopathology of megalencephalic leukoencephalopathy.
This approach opens new avenues for research into memory using zebrafish as model organism,» concludes Dr. Okamoto.
From this research published in Scientific Reports, scientists aim to unravel the causes behind the disease in zebrafish and therefore provide new leads for a treatment for human LCA.
Now research with tiny, transparent zebrafish suggests that some of these bugs do more: altering the activity of individual genes in their host, and potentially shaping the fish's development and physiology.
In order to understand this contradiction, the research group led by Raúl Estévez and Alejandro Barrallo compared genetically - modified zebrafish and mice models — in other words, knock - out organisms that, in this case, do not express the gene MLC1 — with the brain biopsy from an MLC patient.
«Our research used zebrafish to focus on one aspect of this system — how the enterocyte cells inside our intestines respond to a high - fat meal.»
The results of our efforts were published recently in a paper entitled Incorporating RNA - seq data into the Zebrafish Ensembl Gene Build in Genome Research.
In their study, to be published in the online edition of the Proceedings of the National Academy of Sciences during the week of Jan. 26 - 30, researchers from Fukui Prefectural University in Obama, Japan, and the National Human Genome Research Institute (NHGRI), which is part of the National Institutes of Health (NIH), describe the innovative techniques they used to produce genetically modified zebrafish using sperm cells grown under laboratory, or «in vitro,» conditions.
In the research, Rieger treated the zebrafish with pharmacological agents that reduce MMP - 13 activity, with the result that skin defects were improved and chemotherapy - induced nerve damage was reversed.
Rieger conducted her research in zebrafish exposed to paclitaxel, a chemotherapeutic agent used for ovarian, breast, lung, pancreatic and other cancers.
Matthew Oberholtzer, Cape Elizabeth, Maine; University of Maine; mentor: Vicki P. Losick, Ph.D., assistant professor, MDI Biological Laboratory; research topic: A study of cilia importance in zebrafish heart regeneration
Developing innovative zebrafish models for drug abuse research.
Laura Paye, Westfield, Massachusetts; University of Maine Honors College; research site: University of Maine; mentor: Rebecca Van Beneden, Ph.D., professor of biochemistry and marine sciences, University of Maine; research topic: The effect of embryonic arsenic exposure on the sensorimotor behavior of zebrafish (Danio rerio).
Leprosy hijacks our immune system, turning an important repair mechanism into one that causes potentially irreparable damage to our nerve cells, according to new research that uses zebrafish to study the disease.
Dr. Voot Yin talks about how research on the common aquarium fish, the zebrafish, may lead to a drug to regenerate healthy heart tissue after a heart attack.
The learning capabilities of zebrafish have been well - characterized in research.
Initial work at the firm will involve research into a particular drug that, according to tests, can double the rate at which complex tissues in zebrafish regrow after amputation.
The zebrafish facility at SciLifeLab has participated in the development of a high - throughput gene targeting method in zebrafish, presented in the July issue of Genome Research.
His current research is focussed on functional imaging and electron microscopy applied to the study of zebrafish neuronal activity in normal and pathology model conditions.
Dr. Yin had been studying heart regeneration in zebrafish (a common animal model for research) for about ten years.
Currently, zebrafish are showing real promise in heart failure research because zebrafish have the unique ability to repair their own heart muscle.
Enriched by the rapid evolution of these technologies, TEFOR - TACGene has developed a solid expertise in the design, production and use of TALE - N and CRISPR / Cas9 systems, both for its own research projects in cultured cells and in collaboration, in many model organisms, including the rat, zebrafish, Drosophila, and Xenopus as part of the National Infrastructure in Biology and Health TEFOR supported by Investissement d'Avenir programme (2012 - 2019).