Not exact matches
«If you see consistent phenotypes
in different models, the things that are happening are probably important,» says Guo - li Ming of Johns Hopkins University School of Medicine
in Baltimore, Maryland, who led the earlier studies of
Zika in human neural progenitor
cells.
Brain
cells from
different people vary
in their susceptibility to
Zika infections, says infectious disease researcher Scott Weaver, also at the University of Texas Medical Branch but not involved
in the study.
The findings mapping the structural landmarks or epitopes recognized by CD8 +
cells appear
in the January 12, 2017, issue of
Cell Host & Microbe and provide an important tool to track
Zika - specific T
cells in the context of
different disease models.
«We compiled a list of the proteins we thought
Zika and similar viruses like dengue were using to get inside of
cells, and then we looked to see which of these proteins were abundantly present
in the
different cell types of the developing brain,» said Pollen, who did the work with Tomasz Nowakowski, PhD, and a UCSF graduate student Carmen Sandoval - Espinosa, BS, both
in Kriegstein's lab.
• Detect
Zika virus
in blood and urine samples within hours and distinguish between its African and American strains • Distinguish between
Zika and dengue • Discriminate
different types of bacteria, like E. coli • Detect cancer
cell mutations • Detect antibiotic resistance genes • Read human genetic information from saliva sample